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      community how about progesterone cream?

      in Research/Science  23 upvotes 7 months ago
      Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

      community P5P supplementation for fin sides.

      in Treatment  7 upvotes 2 years ago
      P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.

      community Hair loss - Blood work (High DHEAS)

      in Research/Science  8 upvotes 3 years ago
      A user has been taking finasteride for 5 months with no improvement in diffuse hair loss and suspects high levels of prolactin, cortisol, progesterone, and DHEAS, as well as iron, might be contributing to the issue. They are also taking vitamin D to address a deficiency.

      community In God We Trust, Topical Fin/Min with existing ADHD issues

      in Chat  19 upvotes 4 weeks ago
      A 27-year-old male with ADHD is experiencing hair thinning and is starting a treatment with topical finasteride (0.025%) and minoxidil (5%). He is addressing high prolactin levels and low vitamin D, while managing side effects from ADHD medication.

      community Dht normal after taking fin and then dut

      in Treatment  2 upvotes 4 months ago
      The user has been taking dutasteride for 8 months and finasteride before that, with normal DHT levels but high estradiol and prolactin, leading to sexual side effects. The user is disappointed with these results.

      community Fin raised my estrogen but also testosterone?

      in Finasteride/Dutasteride  17 upvotes 10 months ago
      A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

      community Another addition to the Hair loss equation.

      in Treatment  2 upvotes 1 year ago
      The post discusses various hair loss treatments including minoxidil, finasteride, microneedling, vitamins, lifestyle changes, and reducing prolactin levels. The user reports positive results after 4 months of treatment, including increased hair growth.

      community Since there is so much hype for cosmeRNA and HMI-115...

      in Chat  47 upvotes 1 year ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  12 upvotes 2 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community Finasteride influence on other hormones

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      Finasteride can affect hormone levels, potentially causing symptoms like puffy nipples and testicular pain, and may result in elevated prolactin and high testosterone. The user is seeking interpretation of these changes after taking finasteride.

      community My Experience and a Discourse on "DUPA"

      in Treatment  9 upvotes 6 months ago
      The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

      community Hi, I got some regrowth recently and I attribute it to DICLOFENAC

      in Research/Science  8 upvotes 1 year ago
      The user started balding at 16/17 and tried various treatments including minoxidil, finasteride, and dutasteride with little success. They recently started applying diclofenac gel to their bald areas and noticed some hair regrowth, attributing this to diclofenac's ability to lower prolactin levels and its anti-inflammatory effects.

      community Lowering scalp prolactine - Any ideas ?

      in Treatment  2 upvotes 1 year ago
      The conversation is about finding the best method to lower scalp prolactine, with suggestions like P5P and Melatonin. The user also mentions HMI115 as a potential treatment and seeks feedback from those who have tried these methods.

      community Low testosterone and dht. What should I do?

      in Finasteride/Dutasteride  6 upvotes 9 months ago
      The user has low testosterone and DHT levels and is considering taking finasteride for Norwood 2 hair loss with diffuse thinning. They are seeking advice on whether low DHT indicates high sensitivity to DHT in the scalp and opinions on their lab values.

      community Somebody has gotta try this- HMI-115 reference anti-body

      in Treatment  14 upvotes 1 year ago
      The potential of using a specific antibody, HMI-115, as a treatment for hair loss alongside traditional treatments such as minoxidil and finasteride. The user suggests trying either a 240 mg or 30 mg dose to see if it works.

      community hight pre-finasteride estrogen levels

      in Finasteride/Dutasteride  1 upvotes 7 months ago
      A user with high pre-finasteride estrogen levels is asking if they need to normalize their hormone levels before starting finasteride and whether they should postpone dermarolling until they begin finasteride. The user is 21.5 years old.

      community Guide To Finasteride and Avoiding Side Effects

      in Finasteride/Dutasteride  23 upvotes 2 years ago
      The conversation provides a guide on using finasteride for hair loss, suggesting to start with a quarter of a 1mg pill daily after ensuring estradiol levels are within a specific range, and potentially increasing the dose if no side effects occur. It also recommends supplements like DIM, Calcium d-glucarate, and Zinc to manage high estradiol levels and side effects from finasteride.

      community Overcame finasteride side effects

      in Finasteride/Dutasteride  9 upvotes 4 years ago
      The user successfully overcame finasteride side effects by lowering the dosage and adding zinc and vitamin B6 supplements. They also micro-dosed dutasteride and resumed weight lifting.

      community Blood work after 4 month topical fin/min

      in Update  6 upvotes 3 months ago
      After 4 months of using topical finasteride and minoxidil, blood tests showed increased E2, Test, and Prolactine levels. The user is concerned about potential side effects like gyno and is seeking advice on managing these values.

      community No gains after 4 years of min and fin

      in Progress Pictures  92 upvotes 5 months ago
      User has seen no improvement after 4 years of using minoxidil and finasteride, and recently started dutasteride. Suggestions include adding oral minoxidil, microneedling, and considering a hair transplant.