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120-150 / 1000+ resultscommunity Can I use topical steroid along finasteride to reduce scalp inflammation and hairloss?
The user asks if finasteride can be used with the topical steroid betamethasone dipropionate to reduce hair loss and scalp inflammation. The discussion revolves around combining these treatments for better results.
community Anti inflammatories as an adjunct treatment
Anti-inflammatories like curcumin, quercetin, and vitamin E may help with hair loss when used alongside treatments like finasteride and dutasteride. Ketoconazole is also noted for reducing scalp inflammation and improving scalp health.
community Injectable and biofunctionalized fibrin hydrogels co-embedded with stem cells induce hair follicle genesis.
Fibrin-based hydrogels support stem cells for hair follicle regeneration, showing promise for alopecia treatment. They enhance cell viability, maintain stemness, and induce hair growth without teratoma formation.
community Weird response to microneedling
Microneedling can cause sneezing and eye tearing due to nerve stimulation, particularly near the temples and forehead. Some users find it lessens over time, while others prefer using finasteride and minoxidil for hair growth.
community Members with Alopecia! Has anyone tried the “autoimmune protocol” diet? (AIP DIET)
community Recent trials investigating mesenchymal stem cell derived exosomes demonstrate significant increases in anagen duration and hair shaft caliber by upregulating Wnt/beta-catenin pathways.
Exosomes from mesenchymal stem cells can increase hair growth by enhancing anagen duration and hair shaft thickness through the Wnt/beta-catenin pathway. Phase 2 trials show improved hair counts over 24 weeks.
community Acne as a result of Finasteride
community A stress hormone has been found to signal through skin cells to repress the activation of hair-follicle stem cells in mice
Stress can lead to hair loss by affecting hair-follicle stem cells, and this loss is harder to recover from if one has male pattern baldness (MPB). Treatments like finasteride and minoxidil are used to address hair loss, but stress-related hair loss differs from androgenic alopecia.
community Does stress/cortisol increase dht?
community Added micro needling to my routine (currently using topical fin and topical Min)
The user has been using topical finasteride and minoxidil for two years with decent regrowth and recently added microneedling to their routine. They are questioning if the small hairs observed are new regrowth from microneedling or just vellus or miniaturized hairs.
community Cetirizine (Zyrtec), to help with inflammation.
The user experiences an itchy scalp and finds relief using shampoo and Zyrtec, which helps with inflammation. They are unsure if the issue is related to histamines or seborrheic dermatitis.
community diffuse hairloss and pitted nails
community IGE Hair Loss and Miniaturization
A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.
community 2/3 non response rate to pp405?
PP405 showed 31% regrowth in a short trial, but its effectiveness is debated compared to Minoxidil and Finasteride. Some argue AGA isn't scarring, while others believe it leads to fibrosis, affecting treatment outcomes.
community Scalp inflammation cleared after stopping "spoiled" milk - what about follicles,shedding?
Switching milk brands cleared scalp inflammation and other symptoms, but hair shedding continues. The user hopes shedding will stop as hair cycles progress.
community Why does MPB only affect the scalp
Male pattern baldness (MPB) may be influenced by androgen receptors in scalp hair follicles and potentially poor blood flow. Transplanted hair is not immune to DHT, and factors like inflammation and scalp tension might also contribute to hair loss.
community Anybody tried PRP-like cosmetic based on biomimetic peptides?
community Scalp feels worse than ever, dried skin, inflammation or perhaps plaque?
The conversation discusses a user's worsening scalp condition, possibly seborrheic dermatitis, despite using keto shampoo. Suggestions include using MCT C8 oil, adjusting diet by reducing carbs and sugars, and consulting a dermatologist.
community MBP Itch CURE?/ Slow shedding TBD
A user with diffuse hair loss for a decade tried various treatments, including LLLT Helmet, supplements, topicals, and hair transplants. They found relief from scalp inflammation and itching using a topical solution made from crushed Xeljanz pills mixed with ethyl alcohol.
community Am I being a total wimp if scalp micro needling at .5mm with pain and blood?
community I literally can’t find any evidence of sulfotransferase being upregulated by microneedling or retinoids like tretinoin
Microneedling and tretinoin may enhance minoxidil absorption for hair loss, but evidence on their effectiveness is limited. Iron supplements and broccoli sprouts are suggested for enzyme activation, but their impact on hair is unclear.
community Is it ok to take Xeljanz (A jak inhibitor) while taking finasteride?
The conversation is about whether it is safe to take Xeljanz, a JAK inhibitor, while also taking finasteride for hair loss. The concern is that Xeljanz weakens the immune system, which could be risky.
community Preliminary Study on Platelet-Rich Plasma Enhancing Autophagy Level and Promoting Hair Growth in Androgenetic Alopecia Model Mice
Platelet-rich plasma may enhance autophagy and promote hair growth in androgenetic alopecia. Treatments discussed include Minoxidil, finasteride, and RU58841.
community Anyone suffering from MPT and Seborrheic Dermatitis?
community Pelage have presented only phase 2a. The rest of phase 2 for PP405 will be presented at a later medical meeting
PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.
community Scalp scabbing / peeling post microneedling
community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.
Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.
community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...
Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.