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GlossaryPrimary Cilia

small, hair-like cellular structures that sense environmental signals

Primary cilia are small, hair-like structures that extend from the surface of most human cells. They act as sensory antennas, detecting signals from the cell's environment and playing crucial roles in cell communication and signaling pathways. These structures are essential for various biological processes, including development and tissue maintenance, and their dysfunction can lead to a range of diseases known as ciliopathies.

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community Primary Care Provider told me to not be concerned and just take biotin.

in Finasteride/Dutasteride 2 upvotes 1 month ago

A 19-year-old was advised by their primary care provider to take biotin for hair loss instead of minoxidil or finasteride due to potential side effects and age concerns. The user is considering seeking a second opinion from a dermatologist.

community If DHT is the one big primary reason for Hairloss.. Then other reasons are hoax?

in Chat 8 upvotes 2 years ago

The conversation discusses various theories and suggestions for hair loss, with a focus on DHT as the primary cause. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 136 upvotes 6 months ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community We need to keep these snake oil companies accountable.

in Treatment 121 upvotes 5 months ago

Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

community I love Costco. Fin is less than $3 per month without insurance.

in Finasteride/Dutasteride 128 upvotes 8 months ago

The conversation discusses the affordability of finasteride for hair loss treatment, with users sharing that it can be obtained for less than $3 per month at Costco without insurance, and the cost can be further reduced by getting a year's prescription at once. Some users also mention getting prescriptions from their primary care physician or online services.

community Eucapil/fluridil - have you heard of it? What’s your opinion?

in Treatment 3 upvotes 3 months ago

Eucapil/fluridil is discussed as a potential treatment for hair loss, with questions about its effectiveness and why it isn't a primary treatment. Minoxidil, finasteride, and RU58841 are also mentioned as treatments.

community How Do You Get A Dut Prescription?

in Finasteride/Dutasteride 14 upvotes 9 months ago

A user considering switching from finasteride to dutasteride for hair loss is seeking advice on how to get a prescription, with suggestions to ask their primary care physician or consult a dermatologist, and mentions of telehealth options for obtaining the prescription.

community Why do people downplay vitamin deficiency when 94% of Americans are vitamin D deficient?

in Research/Science 132 upvotes 11 months ago

The conversation is about the role of vitamin deficiencies in hair loss and the effectiveness of treatments like Minoxidil, finasteride, and RU58841. It concludes that while vitamins and nutrition are important, they are not the primary solution for androgenic alopecia.

community Testosterone and hair loss seeming irrelevance

in Research/Science 81 upvotes 1 year ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community Anyone knows the Gt20029 approx release date?

in Chat 16 upvotes 6 months ago

A user with stage 1 hair loss is inquiring about the release date of GT20029, hoping to use it instead of Minoxidil and finasteride, as they believe it has better results. They want to know if it will be available in the next couple of years.

community “You can’t regrow hair that’s gone.” HMB

in Progress Pictures 32 upvotes 1 year ago

User regrew lost hair using microneedling, minoxidil, finasteride, Nizoral, fish oil, and collagen peptide. Progress was slow but constant, and patience was important.

community "DHT Itch" and onset Seborrheic Dermatitis

in Research/Science 76 upvotes 1 year ago

The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 week ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community Could this be legit Pyri/KX-826 on sale in USA?

in Product 6 upvotes 4 months ago

A user discusses the legitimacy of Kintor's KX-826 for hair loss, available on Amazon through Koshine Biomedica. They decided to order it after finding a document linking Kintor and Koshine as collaborators.

community 5% capixyl 3%redensyl+procapil

in Product 6 upvotes 9 months ago

The conversation is about a hair loss serum mix containing 5% capixyl, 3% redensyl, and procapil. The user is asking for recommendations or opinions on the effectiveness of this product.

community Hairloss - what hormones to check?

in Finasteride/Dutasteride 10 upvotes 11 months ago

The user is concerned about hair loss despite using oral finasteride, oral minoxidil, and topical minoxidil. They are seeking advice on additional blood tests to identify potential causes.

community if hmi-115 truly works, we can just get off off fin?

in Chat 19 upvotes 1 year ago

A potential new hair loss treatment, HMI-115, and the possibility of discontinuing finasteride in favor of it. The conversation also includes discussion about other benefits of using finasteride.

community HairClone: Good info from their site

in Technology 10 upvotes 2 years ago

HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.

community Does Nuking Scalp DHT Theoretically Make Minoxidil Gains Permanent?

in Minoxidil 35 upvotes 1 week ago

Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.

community My hair journey as a 20+ year old with genetic hair loss and thoughts of pregnancy soon

in Female 1 upvotes 4 weeks ago

A 28-year-old woman with genetic hair loss has tried various treatments, including oral minoxidil, finasteride, dutasteride, vitamins, ketoconazole shampoo, exosome needling, and hair extensions. She plans to pause treatments for pregnancy and is concerned about potential hair loss during that time.

community 2 months of difference with estradiol and spiro (4 months total w/ estradiol & spiro; 4 years of minoxidil and finasteride) (you should not take estradiol or spiro if you look manly and want to continue looking manly)

in Transgender 115 upvotes 1 month ago

Hair regrowth using estradiol, spironolactone, minoxidil, and finasteride, showing significant improvement over four years. HRT is not advised for cis men solely for hair loss due to feminizing effects.

community I know that wanting a cure is unrealistic and too much to ask. But I at least want medicine that will work reliably for almost everyone.

in Chat 51 upvotes 2 months ago

The conversation is about the effectiveness of hair loss treatments like finasteride, dutasteride, and minoxidil. Users agree these treatments help maintain hair but don't guarantee miraculous regrowth, emphasizing early intervention for best results.

community This shit works like magic, aka 50 days on oral min&fin

in Progress Pictures 170 upvotes 4 months ago

A user shared their successful 50-day progress using oral minoxidil and finasteride for hair loss. They plan to switch to dutasteride after six months for potentially better results.

community 5 months on finasteride, have i Even made any progress??

in Is this regrowth? 26 upvotes 5 months ago

A user is questioning their progress after 5 months on finasteride and considering alternatives like dutasteride and minoxidil. Replies suggest that finasteride primarily maintains hair, and combining it with minoxidil might help with regrowth.

community Guys maybe high cholesterol and hair loss are related

in Chat 5 months ago

High cholesterol may accelerate hair loss by reducing blood flow and increasing DHT levels. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Hello again with my second journey

in Transplants 78 upvotes 6 months ago

A user underwent a second hair transplant for increased density and to address hair loss in the crown area, with 3,800 grafts at a cost of 2,200 euros at Estepalace, including additional services. Some commenters discussed the appearance of the hairline and the importance of using DHT blockers like finasteride or dutasteride post-transplant.

community Is it uncommon to not test for testosterone levels before taking fin?

in Finasteride/Dutasteride 13 upvotes 7 months ago

Doctors often prescribe finasteride for hair loss without testing testosterone levels. There is no need for such tests before starting the medication.

community Dermatologist tells me I don't have any serious signs of hair loss. This is my hairline.

in Chat 30 upvotes 11 months ago

A user is confused about a dermatologist's positive assessment of their scalp despite concerns about their hairline. They discuss using oral minoxidil, concerns about side effects from finasteride, and difficulty finding topical finasteride.

community Why are there no posts about LLLT (Low-level laser light therapy) laser caps?

in Technology 12 upvotes 11 months ago

The conversation is about the lack of discussion on Low-level laser light therapy (LLLT) laser caps for hair loss. One user questions their effectiveness, and another asserts they don't work.

community Proposed new pathogenesis model for androgenetic alopecia (AGA)

in Research/Science 8 upvotes 1 year ago

The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.