HMI-115, a newly discovered hairloss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.
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This conversation discussed the efficacy of Minoxidil and Finasteride as treatments for hairloss, with a focus on the potential side effects of taking Oral Minoxidil. Some users shared their experiences with both treatments and there was debate over whether they were safe or not.
The post is about a user's progress with using finasteride, minoxidil, and dermarolling for hairloss. The conversation includes comments about different treatments and methods used.
This user has achieved impressive results after 5 months of using Finasteride and Minoxidil, which appear to have stopped hairloss and stimulated new growth. They have also incorporated derma pen treatments and supplements such as Zinc picolinate and DMAE into their regimen.
Progress (in a good way). How often did you take biotin?
KarensAnon: I took biotin once daily.
KarensAnon has made 3-month progress with the use of Minoxidil foam, 0.5mm micro-needling weekly, and biotin to combat hairloss which had started at age 19. They plan to further their treatment by adding finasteride soon.
A 20-year-old lost significant hair after one year of treatment, using minoxidil, finasteride, and later dutasteride. They are considering adding RU58841 but are advised to return to finasteride and minoxidil for a year before deciding.
The user is seeking confirmation of progress in their hair regrowth journey while using oral finasteride and topical minoxidil. They also mention experiencing shedding and dandruff after switching from liquid minoxidil to foam. Some users suggest considering a hair transplant.
The user has been using finasteride and minoxidil for over three years, switched to oral minoxidil, and recently started dutasteride and dermarolling but still experiences thin hair. They are seeking suggestions for improving their hair condition.
The user stopped finasteride due to testicular aches and switched to minoxidil, seeing positive results in three months. They are considering topical finasteride but are cautious because of past side effects from oral use.
Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hairloss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.
A 14 year old who is experiencing hairloss and has not received any help from the doctor, with advice being given to try different doctors, get tested for underlying conditions and intolerances, buzz it short as an option and treatments that could slow down or reverse the hairloss such as minoxidil, finasteride, RU58841 and addressing the cause of the hairloss.
Hairloss progress pictures can be misleading due to differences in lighting, hair length, and wetness, making it hard to accurately assess changes. Treatments mentioned include minoxidil and finasteride, with some users expressing skepticism about their effectiveness.
The conversation discusses the effectiveness of finasteride and dutasteride in treating hairloss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.
Using oral finasteride in combination with topical minoxidil and dermarolling for hairloss. Some users have reported significant regrowth when adding finasteride to their minoxidil routine, suggesting that reducing DHT levels may be a key factor in hair regrowth.
The conversation discusses the effectiveness of anti-androgens for hairloss, with a preference for topical treatments like RU58841 over oral options due to better scalp concentration and fewer side effects. Topical finasteride at 0.1% may provide some results, especially when combined with a topical androgen receptor antagonist like RU58841.
Saul Goodman was humorously depicted using high doses of minoxidil, finasteride, and spironolactone for hairloss. The conversation jokes about the unrealistic dosages and their potential side effects.
The user regrew their hairline using mechanical stimulation, including a 1.5mm derma roller weekly, daily scalp massages, and other treatments like Nizoral, zinc pyrithione, fish oil, and Lipogaine The Big 5. They did not use Minoxidil or finasteride.
A 31-year-old with diffuse thinning experienced significant hair regrowth after nearly 5 months on Finasteride 0.75mg MWF. Despite initial side effects like testicle pain and reduced sex drive, these issues resolved, and positive effects included reduced nighttime urination and scalp itching.
My hairline, I am only 23.
This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.
A user shared their hairloss journey from 2017 to 2024, detailing the use of finasteride, minoxidil, dutasteride, supplements, and dermarolling. They experienced significant hairloss after stopping finasteride in 2017, saw some regrowth after resuming treatments in 2023, and are considering a hair transplant.
Minoxidil and finasteride together can lead to significant hair regrowth, often noticed gradually over time. Consistent use without stress is key, and while minoxidil helps regrow hair, finasteride prevents further loss.
The user has seen improvement in their hairloss after 6.5 months on finasteride, 8 months on Minoxidil and RU58841, and using Nizoral twice a week. Commenters suggest adding microneedling to the treatment regimen for potentially better results.
Feeding bacteria-free mice with Lactobacillus murinus worsened hairloss, but a regular diet with biotin stopped it. The conversation suggests gut bacteria and diet may influence hairloss, with some skepticism and discussion about other factors like DHT and genetics.
A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.
A user shared their personal theory on hairloss, suggesting it's caused by reduced blood flow and scalp calcification rather than DHT, and claimed to have stopped their hairloss by massaging the scalp, using acid peels, and applying oils and copper peptides. They have not noticed further hairloss for six years since starting this routine.
A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hairloss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.
The conversation reflects on how hairloss was portrayed in older movies as a natural part of aging, contrasting with today's media where balding is less visible due to treatments like finasteride and hair transplants. Participants also discuss the difference in societal attitudes towards hairloss and appearance in past generations compared to the present.
Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.