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GlossaryPotassium Channels

specialized proteins that regulate potassium ion flow in cells

Potassium channels are specialized proteins found in the cell membrane that allow potassium ions (K+) to pass in and out of the cell. They play a crucial role in maintaining the cell's electrical balance and are essential for various physiological processes, including nerve signal transmission, muscle contraction, and heart function. These channels are highly selective, ensuring that only potassium ions can pass through, which helps regulate the cell's internal environment.

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community The Effects of the Potassium Channel Opener Minoxidil on Renal Electrolytes Transport in the Loop of Henle

in Minoxidil 8 upvotes 3 years ago

This post and conversation are about the effects of Minoxidil on renal electrolytes transport in the Loop of Henle. The replies show a lack of interest and a brief summary stating that rectal Minoxidil electrolytes are bad.

community Sustaining minoxidil dependent hairs?

in Research/Science 9 upvotes 10 months ago

Minoxidil-dependent hairs fall out if minoxidil is stopped. New treatments like GT20029, FOL055, or TDM105795 might help sustain these hairs.

community Microneedling to maintain results from min

in Microneedling 7 upvotes 4 months ago

Microneedling alone is not effective in maintaining minoxidil results for hair growth. Combining microneedling with minoxidil and finasteride may enhance results, but microneedling by itself is not a reliable treatment.

community Minoxidil and Caffeine - opposite effects yet comboed together?

in Product 1 upvotes 5 months ago

Minoxidil and caffeine are discussed for hair loss treatment. The user questions the logic of combining them due to their opposing effects on adenosine receptors.

community Please explain this Minoxidil phenomena

in Minoxidil 60 upvotes 1 year ago

The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

community A possible way to reap the benefits of finasteride with no risk of side effects

in Finasteride 15 upvotes 8 years ago

A user suggests that a .25% topical finasteride solution could reduce scalp DHT levels without affecting bloodstream DHT levels, potentially avoiding sexual side effects. They question why a 2.5% solution was chosen and if a custom .25% solution can be ordered.

community me looking at all the hyper responder posts while I'm still losing ground 2 years on finasteride

in Satire 364 upvotes 1 month ago

People are frustrated with hair loss treatments like finasteride, minoxidil, and dutasteride, with mixed results and side effects. Some users suggest trying different combinations or doses, while others express disappointment and hope for a cure.

community New & Improved Hair Growth Stack for Maximum Results

in Treatment 2 upvotes 3 weeks ago

A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

community Update of my case, might have finally found what happened

in Minoxidil 6 upvotes 5 months ago

OP believes RU58841 affected their thyroid, causing hypothyroidism and impacting minoxidil's effectiveness. They plan to start thyroid medication to improve hair regrowth.

community MY Hair Loss Treatment Summary

in Treatment 10 upvotes 8 months ago

The conversation is about various hair loss treatments, including finasteride, minoxidil, RU58841, and natural supplements like saw palmetto and pumpkin seed oil. It also covers methods to improve blood circulation, nourish hair follicles, and address underlying health issues like vitamin D deficiency and high cortisol levels.

community Minoxidil Beard Growth Stack + Protocol (Only 1.5 years commitment)

in Minoxidil 6 upvotes 9 months ago

A user shared a beard growth protocol involving hydration toner, azelaic acid, tretinoin, moisturizer, 5% topical minoxidil, and SPF 30+ sunscreen. The regimen spans a year to a year and a half, with specific application schedules for different phases.

community (comment) providing facts on people talking nonsense about minoxidil and BP-medicaton in general

in Research/Science 17 upvotes 1 year ago

Minoxidil is used for hair loss and sometimes for high blood pressure, but it's outdated for the latter. For high blood pressure, it's combined with a beta blocker and diuretic to manage side effects.

community 18M 10 months on anti-androgens and oral min

in Progress Pictures 50 upvotes 1 year ago

An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hair loss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.

community Two months Fin / oral Min, age 48; same lighting, same haircut

in Progress Pictures 466 upvotes 1 year ago

The user "NotYourMothersDildo" shared their progress pictures after using finasteride and oral minoxidil for 60 days. They noticed significant improvements in hair thickness, texture, and growth, including their mustache and beard.

community My experience and hair transformation journey

in Update 68 upvotes 1 year ago

The user improved their hair density and reduced scalp visibility by using 1% ketoconazole shampoo, 1mg finasteride, and 5% minoxidil, which increased their confidence. Replies discuss the effects of these treatments, with one clarifying that minoxidil does not affect hormones but finasteride does.

community dunno if it's growing anything but it's making my scalp red

in Technology 185 upvotes 1 year ago

Hair loss and potential treatments, primarily focusing on Finasteride and Minoxidil. Other solutions discussed include PRP, dermarolling, LLP, and scalp tension relief.

community Long term minoxidil as a permanent solution

in Minoxidil 26 upvotes 3 years ago

A user is considering using minoxidil for hair loss and asks for advice on application and long-term effectiveness. Responses suggest minoxidil can be effective but may lose efficiency over time, and combining it with other treatments like finasteride might be more beneficial.

community Clearing the air on how non-surgical treatments really work

17 upvotes 5 years ago

Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

community 3 month using minoxidil 5% once a day

in Progress Pictures 304 upvotes 1 month ago

Using minoxidil 5% once a day for hair loss, with suggestions to add finasteride for better results. It also discusses the effectiveness and side effects of finasteride and the importance of consistent application.

community Does Nuking Scalp DHT Theoretically Make Minoxidil Gains Permanent?

in Minoxidil 36 upvotes 3 months ago

Minoxidil gains are not permanent without continued use, even with DHT suppression. Combining treatments like Dutasteride, Finasteride, and RU58841 may help maintain hair, but stopping Minoxidil typically results in hair loss.

community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

in Research/Science 38 upvotes 7 months ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community Does drinking coffee offset the effects of Minoxidil?

in Minoxidil 16 upvotes 10 months ago

The conversation discusses whether drinking coffee affects the hair growth benefits of Minoxidil, with one user mentioning that Minoxidil's vasodilation is stronger than caffeine's vasoconstriction, and another sharing personal experience of better hair growth after quitting caffeine while on Minoxidil.

community 2 month update (30M) - finasteride, minoxidil, dermaroll, nizoral

in Progress Pictures 290 upvotes 3 years ago

Hair loss progress update: finasteride, minoxidil, dermaroll, nizoral. Dermaroll depth 1.5mm, 3 times a week.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 738 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 1 year ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 49 upvotes 1 month ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community Why is Minoxidil not enough for hair loss? (No fin)

in Minoxidil 55 upvotes 2 months ago

Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 4 months ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community For all those worried about a minoxidil break

in Minoxidil 342 upvotes 6 months ago

Stopping minoxidil can lead to significant hair loss, but resuming it along with finasteride can help regain lost hair over time. Consistency is key for maintaining hair health and regrowth.

community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

in Finasteride/Dutasteride 113 upvotes 2 years ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.