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      community Federal Grant Cuts have impacted PP405 related research

       459 upvotes 1 year ago
      Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

      community 25M - 4 month progress on min + fin

      in Progress Pictures  258 upvotes 2 years ago
      A 25-year-old shared his 4-month progress using oral minoxidil, oral finasteride, a 1mm dermastamp, Nizoral, and upgraded shampoo and conditioner. He feels he sees some regrowth, though some commenters attribute the change to a different hairstyle.

      community 3 year update - Dut, Min, Niz. 1.5mm roller

       641 upvotes 1 year ago
      The user shared a 3-year hair restoration update using 0.5mg dutasteride daily, 5% minoxidil foam twice daily, a 1.5mm derma roller twice a month, and Nizoral shampoo. They reported significant improvement and maintenance of hair, with minimal side effects, and are satisfied with the results at age 40.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       23 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community (27M) Seems like first PRP session just worsen my hair...

      7 months ago
      A user experienced worsened hair condition after a PRP session and is considering stopping further sessions. They are using a Dermapen, electric massage, iron, saw palmetto, and plan to start minoxidil, but have had side effects with finasteride and are advised to consider dutasteride under medical supervision.

      community 4 month topical fin/min progress pics

       618 upvotes 1 year ago
      A user experienced significant hair regrowth after 4 months using topical finasteride and minoxidil, along with dermastamping and biotin supplements, without side effects. They are not considering a hair transplant due to the success of this regimen.

      community Five month hair regrowth progress (Dut+min+biotin)

       327 upvotes 3 months ago
      The conversation is about hair regrowth progress using dutasteride, minoxidil, and biotin. The user shares before and after pictures, noting significant improvement and discussing treatment details like derma rolling.

      community UK Shampoo recs - Piroctone Olamine

       1 upvotes 2 years ago
      Piroctone Olamine at 1% is recommended for reducing scalp inflammation and encouraging hair growth. The user seeks recommendations for UK shampoos/conditioners containing this ingredient.

      community PHG Invites

       4 upvotes 10 years ago
      The conversation discusses a community called PHG, which focuses on experimental hair loss treatments and scientific approaches to hair regrowth. It mentions treatments like Minoxidil, finasteride, and RU58841, and highlights interest in new treatments like Setipripant, Histogen, and Replicel.

      community Red and ichy pimples/rash from applying topical minoxidil

       2 upvotes 8 months ago
      The user experienced red pimples and a rash from using topical minoxidil, possibly due to propylene glycol. Suggestions included seeing a dermatologist, switching to foam without propylene glycol, using Nizoral, and adjusting application timing.

      community Topical Fin 0.3/Min 6% - 11 Week progress.

       82 upvotes 1 year ago
      The user applied topical finasteride 0.3% and minoxidil 6% once daily, used keto shampoo weekly, and derma stamped weekly or biweekly. They noticed hair improvement, possibly due to regrowth or letting it grow longer.

      community Blow dryer, sea salt spray, mousse, texture powder

       5 upvotes 2 weeks ago
      Using a blow dryer, sea salt spray, mousse, and texture powder can significantly increase hair volume. These products can improve hair appearance quickly and easily.

      community Possibility of updates or more information on the pp405

       21 upvotes 10 months ago
      The conversation discusses the potential updates on the pp405 trial for hair loss, with completion expected by December 2025. Participants express skepticism about new treatments, suggesting continued use of finasteride, while others hope for innovative solutions beyond current medications.

      community Where do you all get your pg+e

       5 upvotes 3 years ago
      The conversation discusses using stemoxydine as a carrier for RU58841 and the search for affordable, premixed PG+E. Minoxidil is considered as an alternative, but simplicity is preferred.

      community Pumpkin seed oil and alcohol free minoxidil

       23 upvotes 2 months ago
      A 41-year-old male used pumpkin seed oil, alcohol-free minoxidil, rosemary oil, castor oil, and Nizoral shampoo to regrow hair on thinning spots, noticing results within a month. He avoided finasteride, opting for a natural approach, and improved his diet.

      community Scalp Psoriasis and Fin/Min options?

      in Treatment  3 upvotes 8 months ago
      A user with scalp psoriasis and hair loss is hesitant to use topical minoxidil and finasteride due to concerns about psoriasis and potential side effects. They are considering alternatives like pumpkin seed and saw palmetto.

      community Dad 5 months of minox and 4 of fin

      in Is this regrowth?  298 upvotes 1 year ago
      A user shared their dad's progress after 5 months of Minoxidil and 4 months of Finasteride, showing significant hair regrowth. Users discussed the potential for miniaturized hairs to become terminal again, with some expressing hope and others skepticism.

      community What are everyone's expectations for PP405?

      in Chat  10 upvotes 4 months ago
      PP405 is expected to be a promising addition to hair loss treatments, potentially working well with existing treatments like finasteride and minoxidil, but not as a standalone solution. Users are hopeful for its effectiveness, especially in combination with other treatments, though expectations vary.

      community Ginsenoside enriched formulation

      1 year ago
      Panax ginseng, specifically a ginsenoside-enriched formulation, is suggested as a potential hair growth treatment alongside finasteride and minoxidil. The user is considering trying panax ginseng despite limited availability and evidence.

      community Crown progress 3 months (fin + min)

       33 upvotes 6 months ago
      The user shared progress on hair regrowth using finasteride, minoxidil, dermastamp, Nizoral shampoo, and scalp massage, showing significant improvement in three months. The user reported no side effects and asked if early regrowth is normal.

      community How much Propylene Glycol is in your minoxidil?

       3 upvotes 1 year ago
      The conversation discusses the optimal amount of Propylene Glycol in Minoxidil for better absorption. It focuses on enhancing the effectiveness of Minoxidil in treating hair loss.

      community Shedding and sides from pumpkin seed oil? This sounds ridiculous...

       2 upvotes 9 years ago
      Pumpkin seed oil may cause side effects similar to finasteride, such as brain fog, lethargy, and reduced libido, but it hasn't shown positive results for hair loss. Users suggest reducing the dosage or consulting a doctor, and other treatments like finasteride, minoxidil, and hair transplants are mentioned as alternatives.

      community Pumpkin Seed Oil Orally: Safer than Fin with promising results?

       4 upvotes 5 years ago
      Pumpkin seed oil and saw palmetto are discussed as natural DHT blockers with potentially fewer side effects than finasteride. Users share experiences with these treatments, noting concerns about mental health and side effects from finasteride.

      community 2.5 months fin topical / min oral + min topical.

       10 upvotes 4 months ago
      The conversation discusses a hair loss treatment regimen involving finasteride topical, minoxidil oral and topical, pumpkin seed oil, turmeric drink, weekly derma rolling, and regular head massages. Another user plans to start a similar regimen, including finasteride, minoxidil, keto shampoo, and GHK-Cu vials.

      community Is PP405 really that good or another "scam"?

       3 upvotes 7 months ago
      PP405 is considered a potential alternative to minoxidil and finasteride, but its effectiveness and safety are still uncertain. Many users suggest sticking with proven treatments like finasteride and minoxidil due to the lack of long-term data on PP405.

      community More practical progress pictures post followup (1 year oral min 8 months oral fin) (22m)

       6 upvotes 4 months ago
      A user shared progress pictures after one year on oral minoxidil and eight months on oral finasteride, noting improved hair density and recession at the corners. The user also mentioned using volumizing shampoo, conditioner, and a homemade sea salt spray, while others debated the necessity and effectiveness of the treatments.

      community $120 million Series B funding to Pelsge

       57 upvotes 11 months ago
      Pelage Pharmaceuticals received $120 million in Series B funding for hair loss treatment development. The conversation expresses excitement and anticipation for the release and effectiveness of the treatment.