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      community I want to be a science experiment

      in Research/Science 1 year ago
      The user plans to use a "nuclear protocol" for hair improvement, including topical minoxidil 12.5%, topical finasteride 0.1%, and tretinoin 0.05%, with microneedling once a week. They have seen improvements with minoxidil and are seeking opinions on their approach to achieve thicker hair.

      community Anagen (@anagenxyz) claiming they've cracked scalp-only DHT blocking - thoughts?

       15 upvotes 1 week ago
      A company is developing a topical dutasteride that targets hair follicles without significantly affecting systemic DHT levels, with trials underway to measure its effectiveness. Users discuss the potential benefits and skepticism around the formulation compared to existing treatments.

      community Article of all potential future cures

       25 upvotes 1 year ago
      Ritlecitinib and PP405 show promise for hair regrowth. Diagnosing the cause of hair loss is crucial before treatment.

      community is there any news about pp405 please

       10 upvotes 1 year ago
      There is no new information on pp405, with data collection expected to finish by the end of 2025. Users are discussing the timeline for data analysis and completion of Pelage Pharmaceuticals' phase 2 study.

      community The Association between Sugar-Sweetened Beverages and Male Pattern Hair Loss in Young Men

       136 upvotes 1 year ago
      Excessive sugar consumption may contribute to male pattern hair loss by increasing androgen sensitivity and insulin resistance, but genetics play a significant role. Treatments like minoxidil and finasteride are suggested for managing hair loss, while reducing sugar intake and maintaining a healthy lifestyle may help mitigate its progression.

      community TE Shedding for nearly 10 months now

       3 upvotes 1 year ago
      A 20-year-old male experienced significant hair shedding for nearly 10 months, despite using finasteride, oral minoxidil, and ketoconazole, and is concerned about chronic telogen effluvium. He has been supplementing with vitamins and minerals but remains unsure of the cause.

      community its been over 6 months, feeling like a new man

      in Progress Pictures  292 upvotes 1 year ago
      A 20-year-old male experienced significant hair regrowth and transformation in under 7 months using oral minoxidil and finasteride. His hair became curlier, darker, and denser, leading to a dramatic change in appearance.

      community PSA: Greasy, product laden hair makes the scalp 10x more visible

      in Treatment  30 upvotes 1 year ago
      Greasy or product-laden hair can make the scalp appear more visible, leading some to mistakenly think they are balding. Proper hair washing and avoiding heavy products can help assess true hair thickness, and treatments like finasteride are used by some for actual hair loss.

      community 34 MtF Hair progress timeline pics

       38 upvotes 1 month ago
      A 34-year-old MtF individual shared their hair regrowth journey using finasteride, minoxidil, estrogen, cyproterone acetate, and dutasteride, noting positive progress despite some setbacks. They experienced side effects like anxiety from cyproterone acetate and desired effects from estrogen, such as feminine fat distribution.

      community A theory about "embracing" the bald look

      in Chat  173 upvotes 9 months ago
      Baldness and modern fashion trends, with a focus on shaving heads and using treatments like minoxidil to manage hair loss and enhance appearance.

      community 10 months of progress on oral fin and min

       18 upvotes 1 month ago
      The user experienced significant hair regrowth on the crown after 10 months using oral minoxidil, finasteride, and biotin, with initial side effects that settled over time. They are considering whether to increase the dosage or get a transplant for further improvement.

      community Finasteride and “anti-aging” effects

      in Treatment  218 upvotes 1 year ago
      Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

      community PHG Invites

       4 upvotes 10 years ago
      The conversation discusses a community called PHG, which focuses on experimental hair loss treatments and scientific approaches to hair regrowth. It mentions treatments like Minoxidil, finasteride, and RU58841, and highlights interest in new treatments like Setipripant, Histogen, and Replicel.

      community Shedding kind of looks like balding

      in Progress Pictures  11 upvotes 1 month ago
      The conversation discusses hair loss treatments, primarily finasteride, and the effects of shedding, miniaturization, and regrowth. Users share experiences with finasteride, minoxidil, and dutasteride, noting normal shedding patterns and potential regrowth signs like baby hairs.

      community second shed on dutasteride, but a woman

       2 upvotes 1 year ago
      A woman experiencing hormonal hair loss is on dutasteride and bicalutamide, which initially improved her hair, but she is now experiencing a second shedding phase with significant short hair loss. Despite normal hormone levels and no deficiencies, she is unsure if this shedding is normal and seeks advice.

      community Hair looks extremely thin under sunlight!

      in Chat  26 upvotes 1 year ago
      A 22-year-old male experiencing diffuse thinning is using oral minoxidil and finasteride but notices his hair looks thin in sunlight. Suggestions include using hair products, considering topical minoxidil, addressing seborrheic dermatitis, and possibly trying dutasteride or a hair transplant.

      community A Short Recap on PP405 and AAD 2026

      in Update 5 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community abusing caffeine boosts DHT levels!

      in Research/Science  1 upvotes 1 year ago
      Caffeine intake may increase DHT levels, but its impact on hair loss is minimal compared to genetic factors. Excessive caffeine can cause health issues, and its effects on hair loss are not directly applicable to humans based on rat studies.

      community What’s the deal with BPC - 157?

       84 upvotes 2 months ago
      BPC-157 is debated for hair loss, with some claiming it helps, but most agree there's no solid evidence for hair regrowth. Finasteride is mentioned as a common treatment, but results vary.

      community HMI-115 Australian Phase 1 Trial completed?

       20 upvotes 2 years ago
      The post discusses the completion of the HMI-115 Australian Phase 1 Trial for hair loss treatment. The user speculates about the potential early release of the trial results.

      community Pp405 - it has to work. It has to.

       171 upvotes 6 months ago
      Hair loss treatments, including PP405, minoxidil, finasteride, and RU58841, with hopes for future solutions. Participants discuss the emotional impact of hair loss and consider alternatives like hair transplants or acceptance.

      community Results are visible. But will it continue?

       4 upvotes 8 years ago
      A user reported visible hair regrowth after using finasteride for almost six months and inquired if results continue improving over time. They also mentioned using finasteride with sulforaphane and experiencing only minor side effects initially.

      community Does DHT give you a leaner face?

      in Finasteride/Dutasteride  44 upvotes 1 year ago
      Finasteride and dutasteride may increase estrogen levels, leading to water retention and a fuller face. Users discuss managing these effects with lifestyle changes and supplements like zinc and DIM.

      community Hair transplant AI simulations research

       6 upvotes 3 years ago
      A user developed AI software to simulate hair transplants on photos, helping people visualize potential results. The tool offers photo-realistic renderings but advises caution regarding exact outcomes due to various factors.

      community Where can I sign up for hair cloning clinical trials?

       4 upvotes 2 years ago
      The conversation is about a user interested in participating in hair cloning clinical trials due to their fine hair and previous positive experience with clinical trials. They are seeking information on how to volunteer for such trials.

      community Bloodwork: what to test for?

       6 upvotes 6 years ago
      The user has been taking oral Finasteride and topical Essengen 6 Plus for hair loss and is experiencing increased depression. They plan to get bloodwork to check hormone levels and are seeking advice on which tests to include.