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      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  60 upvotes 9 months ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community Estimate of GT20029 on the grey market?

      in Technology  8 upvotes 1 year ago
      The conversation is about when GT20029, a hair loss treatment, might be available on the grey market, with users discussing the challenges of compounding it and speculating it might be available after phase 2 results, similar to pyri. Specific treatments mentioned are pyri, RU58841, and GT20029.

      community Twist1 Group Buy: Yes it’s that easy

      in Research/Science  39 upvotes 2 years ago
      A group buy for testing a compound targeting Twist1 protein as a potential hair loss treatment. Inhibiting Twist1, which keeps hair follicles in growth phase, may prevent hair loss with minimal side effects.

      community Tretinoin every other day? (with daily minoxidil)

      in Minoxidil  1 upvotes 3 weeks ago
      The user is considering using Tretinoin every other day alongside daily Minoxidil to manage hair loss and is concerned about inconsistent absorption affecting regrowth. They have noticed a significant reduction in shedding but are unsure if it's due to Tretinoin or the end of the Minoxidil/finasteride shedding phase.

      community Survived First Monte. Shedding is real

      in Progress Pictures  370 upvotes 7 months ago
      The user is treating hair loss with 1mg finasteride every other day, daily topical minoxidil, and weekly derma rolling, and is considering using hair fibers for special occasions. There is a discussion about the initial shedding phase of minoxidil treatment and the importance of consistent photo conditions to track progress.

      community Daily scalp massages lead to more hair loss or not?

      in Treatment  10 upvotes 1 year ago
      The user applies castor oil and uses silicon scalp massagers daily, questioning if the massages cause more hair loss or if the hairs would fall out naturally. They believe the hairs are in the telogen phase and would shed regardless of the massage.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 1 year ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community 4 months Oral Minoxidil 1.25 mg Daily (33 M)

      in Progress Pictures  520 upvotes 1 year ago
      This user, "ediblediety", has been taking oral minoxidil (1.25 mg daily), keto shampoo and occasional derm-rolling for 4 months to treat their hair loss, and they have experienced a shedding phase after the first few weeks of use. They report improvements in the thickness of their facial and body hair, but note that this may be daunting to women.

      community Disappointing news on Breezula/CB-03-01

       18 upvotes 5 years ago
      The conversation discusses disappointment over only receiving a financial report from Cassiopea instead of trial results for Breezula/CB-03-01, a hair loss treatment. However, there is optimism as the company is advancing Breezula into Phase III trials for men, starting trials for women, and submitting an NDA for their acne product, Winlevi.

      community Any updates on RCH-01?

      in Question  12 upvotes 5 years ago
      The conversation is about seeking updates on the hair loss treatment RCH-01, specifically its next phase and any news from Shiseido. The user recalls someone being in contact with a researcher or company representative.

      community Chances of GT20029 hitting the black market?

      in Treatment  11 upvotes 6 months ago
      The conversation is about the potential availability of GT20029 on the black market and whether users would try it. Participants advise waiting for phase 3 trial results to ensure safety and efficacy.

      community Second Shed recovery Motivation

      in Progress Pictures  149 upvotes 7 months ago
      A user shared their experience with hair recovery after a second shedding phase while using Finasteride. They advise staying consistent with treatment, as it can take 1-2 years or more to see results, and also mention using Ketoconazole but are unsure of its effectiveness.

      community Update to fin 0.25 mg, 4x/week

      in Progress Pictures  65 upvotes 1 year ago
      User reported initial hair regrowth with 0.25 mg finasteride taken four times a week, experiencing a second shedding phase, and no side effects. They also mentioned using RU58841 without success and plan to stop after a year.

      community Second shed, non-stop flaking, itching

      in Treatment  12 upvotes 6 months ago
      The user is experiencing a second hair shedding phase and increased flaking and itching while using minoxidil 5% nightly and microneedling every two weeks, with needle length increasing over time. Other users suggest the hair loss may continue without the use of finasteride.

      community Where is GT20029 already? Grrrr

      in Research/Science  18 upvotes 9 months ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community Any updates or news on Gt20029?

      in Chat  7 upvotes 1 week ago
      There are no updates on GT20029, and concerns about its safety and effectiveness remain. The phase III trial has not started, and there are no new studies or data releases.

      community How long does the RU58841 shed last?

      in Treatment  2 upvotes 6 months ago
      The conversation discusses the duration of hair shedding caused by RU58841. The user is stressed and seeking information on how long the shedding phase lasts.

      community Keto 2% halted my insane shed immediately

      in Ketoconazole  56 upvotes 7 months ago
      Ketoconazole 2% shampoo stopped a user's severe hair shedding after just two uses, a result not achieved by finasteride or oral minoxidil. Some users suggest the shampoo's anti-androgenic properties may help with hair loss, while others think the shedding might have stopped naturally or due to the end of a shedding phase.

      community 1 Year Mark. 1mg Oral Finasteride, 5% Topical Minoxidil 2mL

      in Progress Pictures  196 upvotes 7 months ago
      The user has seen significant hair regrowth after one year using 1mg oral finasteride and 5% topical minoxidil, considering a hair transplant if progress stalls. They experienced an initial shedding phase and temporary erectile dysfunction, but no other side effects.

      community Is Anyone using Latanoprost at all?

      in Product  9 upvotes 7 months ago
      A user discusses using latanoprost, a costly treatment that may extend the hair growth phase and improve hair quality, wondering why it's not more popular. They already use a combination of finasteride and minoxidil and plan to incorporate latanoprost into their routine.

      community Stemoxydin and hair cycle question

      in Treatment  2 upvotes 8 months ago
      The user has been using Finasteride for hair loss and is considering adding alphatradiol, stemoxydine, or 2% minoxidil to their regimen. They are concerned that stemoxydine, which shortens the resting phase of hair, might accelerate hair loss in those not using Finasteride by depleting hair cycles without strengthening miniaturized hairs.

      community 5 years on Finasteride, 1.5 years on Minoxidil Foam

      in Progress Pictures  711 upvotes 9 months ago
      The user has been using finasteride for five years and minoxidil foam for 1.5 years to combat hair loss, experiencing significant regrowth after an initial shedding phase with minoxidil. They shared progress pictures and discussed treatment experiences, including the addition of minoxidil to their regimen after noticing reduced efficacy with finasteride alone.

      community 8 week - sharing Finasteride blood test update

      in Progress Pictures  6 upvotes 11 months ago
      A 32-year-old male started taking 0.5mg of finasteride daily for hair thinning and, after 8 weeks, experienced a 70% reduction in DHT and an increase in estradiol; he is currently in the shedding phase of treatment and questioning if the dosage is correct based on his DHT levels. He began with a lower dose due to already low normal testosterone and DHT levels.

      community From n5 to n3 going n2 , 1 year 2mos progress

      in Progress Pictures  373 upvotes 1 year ago
      The user improved their hair loss from stage 5 to stage 3 using Minoxidil, Finasteride, and a Dermapen. They saw results after 6 months, experienced a shedding phase, then saw more gains, advising others not to be discouraged during the shedding phase.