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GlossaryProstaglandin Analogs (PG Analogues)

synthetic compounds mimicking prostaglandins, affecting hair growth

Prostaglandin Analogs are synthetic compounds that mimic the action of prostaglandins, which are naturally occurring substances in the body involved in various physiological processes, including inflammation and the regulation of blood flow. These analogs are commonly used in medical treatments, such as for glaucoma to reduce intraocular pressure and in some cases to promote hair growth, as they can influence hair follicle activity.

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community What happened to all the people here who posted about starting pyrilutamide?

in Research/Science 26 upvotes 1 year ago

People who had posted about using pyrilutamide for hair loss, but did not return with an update; the potential side effects of pyrilutamide, RU58841 and other treatments such as minoxidil and finasteride were discussed.

community Pyrilutamide real life results?

in Research/Science 15 upvotes 1 year ago

The results of using Pyrilutamide, a hair loss treatment available on the gray market, and other treatments such as Minoxidil, Finasteride and RU58841.

community Pyrilutamide Phase 2 Results Release Date: June 2022

in Research/Science 106 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Pyrilutamide Phase 2 results are expected in June 2022, with hopes for a better alternative to current treatments.

community Topical Dutasteride is Here.

in Finasteride/Dutasteride 153 upvotes 3 years ago

The availability of Topical Dutasteride, a potential treatment for hair loss, which can be purchased without prescription from MinoxidilMax. Other treatments discussed include Topical Finasteride and PRP injections, with discussion around dosage, efficacy, side-effects and safety.

community Isn’t Minixidilmax’s PG solvent just superior to the Anageninc K&B solvent

in Product 1 upvotes 4 months ago

PG solvent is considered superior to K&B solvent for RU58841 and Pyralutamide due to cost and effectiveness. The user questions why they should use K&B when PG offers more benefits.

community PG causing irritation when applying RU

in Research/Science 1 year ago

The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

community Making PG free solution at home

in Product 1 upvotes 5 months ago

A user wants to make a solution for RU58841 and finasteride powder using only glycerin and asks if ethanol is necessary. They are seeking advice on whether glycerin alone is sufficient.

community Anyone using Finastopic (no pg Isdin)?

in Product 2 upvotes 6 months ago

The conversation discusses the use of Finastopic, a carrier for finasteride solutions by Isdin, and compares it to a standard propylene glycol (PG) solution. The user was prescribed a 1% finasteride solution using Finastopic and has been using a self-compounded 0.025% topical finasteride with minoxidil.

community RU58841 KB Solution vs PG + Ethanol

in Research/Science 6 upvotes 9 months ago

The conversation discusses the differences between KB solution and PG + Ethanol solution for RU58841 in treating hair loss. It compares the effectiveness and properties of these two solutions.

community RU58841 carrier - PG/Ethanol vs KB solution?

in Treatment 2 upvotes 3 years ago

The conversation discusses the differences between PG/Ethanol and KB solutions for RU58841 application, focusing on potential scalp irritation. KB solution is suggested for those allergic to PG, though both contain ethanol which can dry the scalp.

community Can use olive oil instead of PG (propylene glycol) or glycerin in topical finasteride preparation?

in Finasteride/Dutasteride 2 upvotes 3 months ago

A user asked if olive oil can replace propylene glycol or glycerin in topical finasteride preparation. Another user advised against it, suggesting MCT oil instead due to olive oil's potential to worsen dandruff and seborrheic dermatitis.

community Topical Finasteride -- Without Propylene Glycol (PG)

in Finasteride/Dutasteride 2 upvotes 3 years ago

The user seeks alternatives to Propylene Glycol (PG) for delivering topical finasteride due to scalp irritation. They consider using Propanediol 1,3 and ask for other suggestions.

community Any good place to get Minichek 5 or similarly inexpensive PG-free min?

in Minoxidil 1 upvotes 1 year ago

A user is seeking recommendations for purchasing Minichek 5% solution, a PG-free minoxidil, due to a contact allergy to propylene glycol. They are looking for an affordable option comparable in price to Kirkland or Amazon brand minoxidil.

community Just ordered RU58841 powder should I make my own solution with ethanol/PG or just mix into a bottle of minoxidil?

in Treatment 6 upvotes 3 years ago

The conversation is about using RU58841 powder for hair loss treatment and whether to mix it with ethanol/PG or Minoxidil. The user has been using Minoxidil for years with less efficacy and is considering the best method for combining treatments.

community Any UK sources for minoxidil+RU58841 solution together? That doesn’t contain PG?

in Treatment 2 upvotes 5 months ago

A user is seeking a UK source for a combined minoxidil and RU58841 solution that doesn't contain scalp-irritating ingredients. They specifically want a product without propylene glycol (PG).

community My Vitamin D (25-0H) levels came <4.20 ng/ml (<20 implies deficiency)and B12 came 184 pg/ml (Should be between 211-911). I have a lot of dandruff. The derm has prescribed me with 60k vitamin d tablet once a week and multivitamins for a month. Vitamin deficiency implies TE no? or is it MPB?

in Treatment 38 upvotes 3 years ago

The conversation discusses hair loss treatments, focusing on vitamin D and B12 deficiencies, and mentions using finasteride. It also suggests getting a biopsy to differentiate between MPB and other conditions.

community Just ordered RU powder, a scale, beaker, ethanol and PG. This will be my final attempt.

in Treatment 7 upvotes 1 year ago

The user is trying RU58841, oral minoxidil, and dermarolling to combat hair loss caused by increased scalp testosterone after using finasteride and dutasteride. They plan to document their results.

community Best solution for pyrilutamide in UK?

in Treatment 9 months ago

The user is looking for a PG-free solvent in the UK or EU to make their own pyrilutamide solution for hair loss and is currently using finasteride, considering minoxidil. They hope pyrilutamide will help stabilize their hair loss.

community What’s the highest minox % you home brewed ?

in Minoxidil 2 upvotes 4 months ago

A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

community Question about RU58841 in minoxidil

in Minoxidil 5 upvotes 3 years ago

The user is considering adding RU58841 to liquid minoxidil without propylene glycol (PG) due to an allergy and is asking if this combination is effective and if PG is necessary. They have been using finasteride and minoxidil foam, plan to use RU58841 with liquid minoxidil in the evening, and continue finasteride.

community The best vehicle/carrier for RU58841

in Treatment 2 upvotes 1 year ago

The conversation is about the best vehicle for RU58841, comparing trichosol and Garnier/Vichy Stemoxydine, avoiding propylene glycol (PG) or ethanol due to previous scalp damage. The user is also seeking sources for these products in the EU.

community What do you mix your RU58841 powder with?

in Product 1 upvotes 1 month ago

RU58841 powder is mixed with a 70% ethanol and 30% propylene glycol solution, with some users seeking PG-free alternatives. Minoxidil is also mentioned as a treatment option.

community Kintors interim report from 9-2-24 for everyone whos interested

in Product 32 upvotes 2 months ago

Kintor plans to release pyrilutamide foam and a plant-based Koshine by year-end, with GT20029 progressing in their pipeline. Users are pleased about the absence of propylene glycol (PG) in the new products.

community About to order topical finasteride from compounding pharma what carrier should I choose?

in Chat 2 upvotes 3 months ago

A user is considering ordering topical finasteride with castor and rosemary oil from a Turkish pharmacy. They are debating whether to include the oils or use only PG and ethanol as the carrier.

community blood DHT levels shot up after doubling dutasteride dosage

in Finasteride/Dutasteride 20 upvotes 6 months ago

A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

community Dht bloodwork results. Currently on topical fin for 4 months.

in Chat 2 upvotes 11 months ago

JeremySoCa's DHT level was 29 ng/dl, considered low, and Estradiol was 26.1 pg/dl within the normal range. They are using topical finasteride for hair loss and had a thyroidectomy due to Graves' disease.

community Irritation from topical min (maybe propylene glycol)

in Minoxidil 7 upvotes 1 year ago

User experienced scalp irritation from Kirkland 5% liquid minoxidil, likely due to propylene glycol. They are seeking non-PG liquid alternatives that are affordable.

community Pyrilutamide solution question

in Research/Science 9 upvotes 2 years ago

The conversation is about the stability of pyrilutamide in different solutions. The user is asking if a 70/30 ethanol/pg solution with 4% water will degrade pyrilutamide.

community RU58841 vehicle penetration (Study for minoxidil)

in Treatment 12 upvotes 1 year ago

The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

community Pyrilutamide should not be mixed with Minoxidil?

in Product 7 upvotes 2 years ago

Pyrilutamide should not be mixed with Minoxidil because the water in Minoxidil can degrade it. It's suggested to apply Minoxidil first, wait an hour, then apply Pyrilutamide.