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      community I hope ET-02 or PP405 will be released in the next 4-5 years

       18 upvotes 1 year ago
      PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

      community Do Platelet-rich plasma, PRP work?

      in Research/Science  13 upvotes 3 years ago
      Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

      community Laser Diode Cap, I already use Oral Fin, Topical Min 5%, Nizoral and Microneedling

      in Treatment  1 upvotes 10 months ago
      The user is seeking advice on maximizing hair growth while using oral finasteride, topical minoxidil, Nizoral, and microneedling, and is considering adding a laser diode cap, topical finasteride, retinol, and caffeine. Suggestions include using tretinoin with minoxidil for better absorption, switching to dutasteride, and considering RU58841 or pyrilutamide.

      community You guys saved me (1 year progress)

       1198 upvotes 7 months ago
      The user experienced significant hair regrowth and improved hair health using topical minoxidil, oral finasteride, microneedling, and ketoconazole shampoo. Other users discussed the effectiveness and side effects of finasteride, dutasteride, and RU58841, with some expressing concerns about potential side effects.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

       34 upvotes 8 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community RU58841 KB Solution vs PG + Ethanol

       6 upvotes 2 years ago
      The conversation discusses the differences between KB solution and PG + Ethanol solution for RU58841 in treating hair loss. It compares the effectiveness and properties of these two solutions.

      community Surprise Hair Loss Breakthrough: A Sugar Gel Sparks Robust Regrowth

       129 upvotes 11 months ago
      A sugar gel is claimed to spark hair regrowth, but users express skepticism, noting that minoxidil and finasteride remain the most effective treatments. Many users joke about frequent "breakthroughs" that work on rats but not humans, and some mention the potential of PP405 as a future treatment.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       23 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community Fucking Broccoli! Is this where it's at?

       2 upvotes 2 years ago
      The user has been using finasteride and minoxidil for hair regrowth, with positive results, and recently added daily broccoli consumption, noticing improved hair thickness. Another user suggests that leg exercise, not broccoli, might be contributing to the hair improvement.

      community Any updates on upcoming hair loss medication?

       17 upvotes 2 years ago
      The conversation discusses updates on hair loss treatments, specifically GT20029, PP405, and a rumored injectable peptide from UT. GT20029 is seen as a promising treatment expected within 5-7 years.

      community Anyone tried Hairgenetix copper peptide serum?

       3 upvotes 3 months ago
      Users discussed using Hairgenetix copper peptide serum with microneedling to improve hair strength and reduce shedding, though new hair growth was not confirmed. Some users also mentioned using minoxidil and expressed mixed opinions on the effectiveness of peptides.

      community Plant-based Exosomes Efficacy Sourced from South Korea

       2 upvotes 1 year ago
      Plant-based exosomes for hair loss lack scientific evidence and are considered high-risk with low evidence. Combining PRF with minoxidil and finasteride is suggested as a better option.

      community Let Me Sell You on NAC

       17 upvotes 7 years ago
      The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

      community Tressless ChatGPT AI is GOAT..

       30 upvotes 2 years ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss. Users find ChatGPT a helpful tool for researching these treatments.

      community Mineral deficiencies vs MPB vs Thyroid

       8 upvotes 1 year ago
      The user experienced hair improvement using a topical finasteride, minoxidil, and tretinoin combo, along with supplements like zinc, copper, magnesium, vitamin D3, K2, iodine, and boron. They believe these changes are due to addressing mineral deficiencies and possibly thyroid issues, despite skepticism from others.

      community Anyone looking at peptides for hair?

       9 upvotes 7 months ago
      The conversation discusses interest in peptides for hair loss, specifically mentioning ahkCU and ghkCU. A user is considering adding ghkCU to their treatment regimen.

      community Reasonable and safe stack? Bloodwork within.

       1 upvotes 2 years ago
      A 26-year-old male is using a combination of clomiphene, minoxidil, tadalafil, bupropion, and lisdexamfetamine to address low testosterone, ED, depression, and focus issues. He seeks input on the safety and efficacy of this regimen, which also includes magnesium, zinc, and fish oil supplements.

      community Ben Greenfield Podcast : CHK-Cu & C-60

       4 upvotes 5 years ago
      CHK-Cu (copper peptide) and C-60 (branched carbon chain) are discussed as potentially more effective than minoxidil for hair regrowth. Some users are skeptical about the claim that DHT isn't the root cause of hair loss, and others are trying these products to see if they work.