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      community Swapping from Fluridil to Pyrilutimide?

       1 upvotes 7 months ago
      The conversation discusses hair loss treatments, with the main focus on using Fluridil and considering switching to Pyrilutamide. Other treatments mentioned include minoxidil, topical finasteride, nizoral shampoo, and saw palmetto supplements, with advice to stick with Fluridil for at least six months before considering alternatives.

      community Be careful about using non-PG based alternatives of Minoxidil (mathematically speaking, haven’t seen much practical studies)

      in Research/Science  7 upvotes 1 month ago
      Minoxidil formulations often use propylene glycol (PG) for stability and effectiveness, but PG-free alternatives like foams and PEG-based solutions can also be effective with less irritation. Concerns exist about the quality of PG-free minoxidil from lesser-known brands, especially from India, due to potential manufacturing issues.

      community Websites to get 2% keto shampoo and aminexil?

       2 upvotes 1 month ago
      The conversation is about finding 2% ketoconazole shampoo and aminexil for hair loss treatment. Suggestions include using Amazon's online prescription service or telehealth for obtaining the shampoo.

      community Starting ketoconzole. How much and How many times a week?

      in Ketoconazole  12 upvotes 1 year ago
      A user is experiencing severe dandruff and hair loss, considering using ketoconazole shampoo 2% to manage these issues. They seek advice on application frequency and effectiveness, with suggestions to use it 2-3 times a week and to consider other treatments like finasteride for hair loss.

      community What happened with verteporfin?

       30 upvotes 1 month ago
      Verteporfin, combined with microneedling, shows promise for hair regrowth by allowing hair follicles to grow in wounds, but it's expensive and painful. Pai-1 inhibitors may also help prevent hair loss by degrading fibrosis, and some users continue using minoxidil alongside these treatments.

      community the ordinary retinol & minoxidil

      in Minoxidil  13 upvotes 1 year ago
      Using retinol with minoxidil may not be as effective as tretinoin, but retinaldehyde or adapalene could be alternatives. A micro-roller with minoxidil is suggested for better results.

      community DIY Cetirizin topical 1% with micro needling

       2 upvotes 8 months ago
      The conversation is about using a DIY topical Cetirizine 1% solution with microneedling for hair loss treatment. Concerns were raised about potential side effects and the effectiveness of Cetirizine for this purpose.

      community What’s in Your 'Dream' Topical?

      in Treatment  6 upvotes 1 year ago
      The conversation discusses creating a personalized topical treatment for hair loss, with ingredients like finasteride, minoxidil, tretinoin, melatonin, caffeine, and others. Users share their ideal formulations, including combinations of minoxidil, finasteride, tretinoin, adenosine, and other compounds, while also discussing the importance of managing inflammation.

      community Zinc Pyrithione for pattern hair loss.

       4 upvotes 5 years ago
      Zinc pyrithione and ketoconazole shampoos may help reduce hair loss by removing DHT from the scalp. Users discuss various treatments, including minoxidil, finasteride, and non-pharmaceutical options like castor oil and dermarolling.

      community What helps y’all with reducing all the dandruff from Minoxidil?

       4 upvotes 8 months ago
      The conversation is about managing dandruff caused by using Kirkland minoxidil, with suggestions including using Kelual DS, Nizoral, and exfoliating with oils. Some users also recommend oral minoxidil and finasteride for better results and convenience.

      community Fagron TrichoTest says Finasteride won't help

       10 upvotes 2 years ago
      The user received a Fagron TrichoTest indicating that Finasteride, Dutasteride, and Minoxidil are not effective for them, recommending Latanoprost, Spironolactone, IGrantine-F1 TM, and Trichoxidil instead. Other users expressed skepticism about the test's validity and suggested sticking with proven treatments like Finasteride and Dutasteride.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 10 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Better Than Minoxidil? Topical Sodium Valproate

       50 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Influencers and their recommendations

      in Satire  6 upvotes 9 months ago
      Bryan Johnson uses Dutasteride, Latanoprost, Minoxidil with Tretinoin, and other unproven treatments, while Derek uses Finasteride, Minoxidil, Nizoral, RU58841, and Castor Oil. Kevin uses Finasteride, Minoxidil, RU58841, and Alfatradiol, but is against Nizoral and microneedling, preferring Tretinoin for absorption.

      community RU and cetosomal minoxidil topical

       1 upvotes 7 months ago
      Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

      community Currently Trending Twitter Post: Clascoterone Hailed as New Cure

       1897 upvotes 9 months ago
      Clascoterone is being discussed as a promising new hair loss treatment, showing significant improvement in trials. Despite this, skepticism persists about its effectiveness, cost, and side effects, with some users preferring minoxidil and finasteride.

      community KX-826 0.5% BID ~2 months monotherapy(?) results

       8 upvotes 1 month ago
      The user reported positive results using KX-826 0.5% twice daily for hair loss, noting progress in the temple area with no systemic side effects. They avoided finasteride and minoxidil due to concerns about side effects and inconvenience, respectively, and used ketoconazole shampoo for seborrheic dermatitis.

      community Quercetin got rid of my scalp soreness

       4 upvotes 1 year ago
      Quercetin reduced scalp soreness and may help with histamine-related hair loss. The soreness felt like inflamed follicles beneath the scalp surface.

      community Best hair loss shampoos with active ingredients in 2026?

       1 upvotes 5 months ago
      The conversation is about finding effective hair loss shampoos with active ingredients like ketoconazole, caffeine, saw palmetto, or zinc pyrithione. The user seeks recommendations on effective products, side effects, scalp sensitivity, and usage frequency.

      community Shampoo recommendations for daily hair wash? (Not ketoconazole)

       5 upvotes 1 year ago
      The conversation is about finding a suitable daily shampoo for thin, low-volume hair while using treatments like oral finasteride and minoxidil with caffeine and tretinoin. Recommendations include L’Oréal Ever Pure, baby shampoo, and Waterman’s Grow Me, with some users suggesting ketoconazole for scalp health.

      community Does ketoconazole reduce systemic DHT by much?

      in Treatment  6 upvotes 1 year ago
      Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.

      community Pyrilutamide from Ligand Chem in the UK

       4 upvotes 3 years ago
      Pyrilutamide from Ligand Chem was used by several individuals to address hair loss, with mixed results and no significant side effects reported. Some users switched to Minoxidil Max for better value, while others noted no hair growth or only a reduction in shedding.