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A user has been taking finasteride 1mg for 10 years without side effects but is concerned about high estradiol levels affecting weight loss. Another user suggests using estradiol blockers under medical supervision to manage the levels.

The user has been using finasteride, dutasteride, minoxidil, and a dermaroller/dermastamp for hair loss, reporting positive results and no significant side effects. They switched from finasteride to dutasteride for better results and apply topical minoxidil despite having braids.

The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.

PP405 is being discussed as a promising hair loss treatment, potentially effective when combined with minoxidil and pyrilutamide. Some users are skeptical about rapid hair regrowth claims, while others are considering alternatives like GT20029 and pyrilutamide instead of finasteride.

The conversation humorously discusses hair loss treatments, specifically finasteride, minoxidil, and dutasteride, and their prevalence in Japan. It highlights the common use of these treatments among Japanese salarymen and the ease of obtaining them online or through clinics.

The conversation discusses adding finasteride (Propecia) to a liquid containing stemoxydine for hair loss treatment. The user is inquiring about the effectiveness of this combination.

Clascoterone 5% solution (Breezula) is a promising alternative for androgenetic alopecia, showing continued hair growth with consistent use and no significant side effects. It may be suitable for those who cannot tolerate finasteride or dutasteride, especially when trying to conceive.

Dutasteride users report mixed results, with some experiencing shedding and others seeing no improvement or hair regrowth. Many users also discuss using finasteride and minoxidil, with some preferring topical treatments for better results.

He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

People are sharing their experiences with different dosages of dutasteride and finasteride for hair loss. Many report shedding initially but some see improvements over time, with some also using minoxidil.

User Kylo313 used dutasteride for 20 years and had two daughters, questioning if dutasteride affects the likelihood of having male vs female children. Replies mostly request hairline photos and discuss anecdotal experiences, with some suggesting correlation doesn't imply causation and that gender determination isn't affected by dutasteride.

The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

OP is using 0.5mg dutasteride, 5mg biotin, 5% topical minoxidil twice daily, and dermarolling 1-2 times a week for hair loss. OP reports no side effects and is happy with the progress after 5 months.

User creates 0.1% topical finasteride solution using Alfatradiol Avixis base. Seeks help to ensure alfatradiol base dissolves finasteride.

The user added Dutasteride to their routine, which reduced hair loss, and is considering reintroducing Pyril at a lower dose of 0.5 ml to save costs. It is suggested that 0.5 ml can still be effective if spread properly.

The conversation discusses whether to get a blood test to check DHT levels while using Dutasteride for hair loss and concerns about Quercetin's potential interaction with Dutasteride. It concludes that testing DHT isn't necessary unless no effects are seen, and the small amount of Quercetin in a multivitamin likely doesn't interfere with treatment.

A 30-year-old man experienced significant hair regrowth and improved libido after using finasteride and dutasteride for androgenetic alopecia, with no adverse effects. He plans to reduce dutasteride dosage when trying to conceive and has been using topical minoxidil since 2015.

PP405 is expected to be more expensive than finasteride and minoxidil initially due to patent protection, but not as costly as life-saving medications like Ozempic. The price may decrease after the patent expires, but initially, it might be around $100 per month, making it potentially unaffordable for many.

The user shared progress on hair regrowth using oral dutasteride, oral minoxidil, and verteporfin procedures. They reported some regrowth after 6-9 months of treatment.

Pyrilutamide, a hair loss treatment, is undergoing clinical trials in China and may be available in a few years. Users discuss the possibility of obtaining it early through group buys and synthesis by labs.

A user experienced hair retention but sexual side effects after using dutasteride for a year. Others shared similar experiences with finasteride and dutasteride, suggesting consulting a doctor for persistent issues.

The user has been using 1mg finasteride, 2% ketoconazole shampoo, vitamins, and growth shampoo for 7.5 months to treat hair loss and is considering switching to 0.5 mg dutasteride due to slight recession and persistent symptoms. Another user commented that the user's temples appear to have improved, especially in the latest photo.

A 34-year-old man has used finasteride for 10 years and dutasteride for 1 year to manage hair loss, experiencing minimal side effects and slight hair thinning. He plans to continue using finasteride, ketoconazole shampoo, and oral liquid finasteride, noting that cost and convenience influenced his dosage choices.

The conversation is about using a dermastamp for hair loss treatment and concerns about a potentially scam product, pp405. It suggests sticking with known treatments like finasteride and minoxidil.

A woman experienced hair regrowth after using self-prescribed finasteride and dutasteride from online sources, despite doctors' reluctance to prescribe these due to potential birth defects. Her dermatologist acknowledged the effectiveness of these treatments and advised her to continue using them while avoiding pregnancy.

Concerns about hair loss treatments like finasteride and minoxidil not being administered during a coma. Dutasteride remains in the system longer, and hair loss may not be immediate if treatment stops temporarily.

The user switched from finasteride to dutasteride after 1.5 years without results. They are hopeful the new treatment will work.

The conversation discusses skepticism about the efficacy of Dutasteride bought from a Jan Aushadhi store, with the user planning to take it once a week alongside Finasteride. Some users suggest alternatives like Duprost from Cipla, while others express doubts about government-supplied products.

Dutasteride is generally considered more effective than finasteride for hair regrowth, with some users experiencing better results, especially at higher doses. However, individual responses vary, and some users report side effects or no response to either treatment.

PP405 is a medicine, and Google Ventures is funding its development based on evidence from each phase, unlike their investment in Juicero, which was a trend-based gamble. Investing in medicine is a calculated risk, not reliant on being "cool."