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      community First patient dosed with Pyrilutamide (Kintor) Phase III

       199 upvotes 4 years ago
      First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.

      community How to protect hair while on cycle

      1 week ago
      The conversation is about protecting hair while using testosterone, proviron, and masteron. Suggested treatments include RU58841, dutasteride, and topical solutions.

      community L Doctor criticized my fin usage and suggested minox and HT as alternatives

       35 upvotes 1 year ago
      A doctor criticized the use of Finasteride for hair loss, suggesting Minoxidil and a hair transplant instead, despite the patient experiencing no side effects from Finasteride. The patient disagreed, arguing that Minoxidil doesn't address the root cause and that Finasteride is necessary to protect donor hair in transplants.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

       413 upvotes 1 year ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Dr Couto consultation and finasteride

       6 upvotes 3 years ago
      Dr. Couto recommends taking finasteride in the morning to align with peak testosterone and DHT production for better effectiveness. Oral minoxidil is acknowledged as better than topical, but the focus is on stabilizing hair loss with finasteride first.

      community Indian Is The Best Place To Go Bald.😹

       155 upvotes 1 month ago
      Hair loss treatments like topical Minoxidil with Finasteride and Dutasteride are discussed, highlighting their low prices in India. The conversation also touches on the affordability of medications in India due to mass production and government subsidies.

      community The likely cost of HMI-115, when it comes out

       13 upvotes 3 years ago
      A new potential hair loss treatment called HMI-115, and the cost of this treatment which may be expensive due to production costs but could be competitive with other treatments such as hair transplants.

      community Third shedding phase on less than 6 months of treatment

      in Chat  7 upvotes 3 months ago
      The user has been using minoxidil for almost 6 months and finasteride for almost 4 months, experiencing significant shedding and minimal stabilization. They are considering switching to dutasteride if no improvements are seen and are advised to be patient, as results may take up to 2 years.

      community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

       211 upvotes 1 year ago
      PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

      community JXL082 is not PP405 and Everychem followed the wrong lead

       41 upvotes 1 year ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community 8 years of hair loss, turning 30 next month

      in Progress Pictures  151 upvotes 1 year ago
      The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

      community I have not seen a single person who claims dutasteride destroyed their hair post a picture of the before/after

      in Finasteride/Dutasteride  123 upvotes 2 years ago
      The conversation discusses skepticism around claims that dutasteride worsens hair loss, with some users suggesting misinformation or panic during shedding as reasons for such claims. One user shared their negative experience with dutasteride, including increased sebum production and hair loss, and is now considering a higher dose of oral minoxidil after stopping dutasteride.

      community Clearing the air on how non-surgical treatments really work

       16 upvotes 7 years ago
      Treatments for hair loss, including finasteride, dutasteride, minoxidil, ketoconazole, microneedling, and low level laser light therapy, which aim to reduce DHT production, increase cell absorption and blood flow, and stimulate epidermal stem cells. It also stresses the importance of patience when using these treatments.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 1 year ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community Thoughts about ORAL ketoconazole? (pills)

      8 months ago
      Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

      community Need some advice on Hair Transplant

       4 upvotes 2 days ago
      The conversation is about planning a hair transplant in Turkey, with advice on choosing clinics and doctors, focusing on factors like doctor involvement, clinic reputation, and realistic graft limits per session. Users recommend not exceeding 4000 grafts per session to avoid donor area damage and suggest considering two separate procedures for better graft survival.

      community Can Whey Protein isolate make your AGA worse?

       9 upvotes 3 years ago
      Whey protein isolate may worsen androgenetic alopecia (AGA) due to its potential to increase DHT levels, but finasteride use has helped maintain hair. Some users suggest avoiding protein supplements due to possible contaminants and additives that could affect hair health.

      community Don't use PP405 from everychem. it is likely fake.

       63 upvotes 1 year ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community Sandalore: a scientific homemade approch

       19 upvotes 7 years ago
      The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

      community Regrowth after 3 months. Min only

      in Is this regrowth?  181 upvotes 1 year ago
      A 38-year-old man is using topical and oral Minoxidil, DHT blocker shampoo, and microneedling for hair regrowth, with plans to add Finasteride later. Many users suggest starting Finasteride or Dutasteride immediately to address the root cause of hair loss, while some express concerns about potential side effects.

      community Hair Loss Inflammation Prevention Stack

       48 upvotes 1 year ago
      The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.