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      community Average r/bald user complaining

       401 upvotes 9 months ago
      Hair loss treatments like Minoxidil, finasteride, and RU58841, focusing on their effectiveness and side effects. It also highlights the disparity in medical research funding between hair loss and conditions like endometriosis.

      community stemoxydine - how much to actually use?

      in Treatment  3 upvotes 1 year ago
      The conversation discusses using stemoxydine for hair loss, with OP considering using 1.5 ml daily despite the recommended 6 ml. Some users doubt its effectiveness, while others report positive experiences using similar amounts.

      community RU-58841 without finassteride?

      in Treatment  6 upvotes 1 year ago
      RU58841 is used without finasteride by some due to side effects, with mixed results. Users report combining RU58841 with minoxidil and adjusting finasteride doses to manage hair loss.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

       124 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Inhibition of collagen synthesis, oral versus topical minoxidil

       4 upvotes 3 years ago
      The conversation discusses the use of oral versus topical minoxidil for hairline recession, with concerns about collagen synthesis inhibition. Oral minoxidil may affect collagen production more broadly, while topical minoxidil's effects are localized but may cause skin issues.

      community Do you think clascoterone is overhyped

       14 upvotes 4 months ago
      Clascoterone is considered overhyped and not as effective as finasteride or dutasteride, but it may be useful as a supportive treatment in combination with other therapies. Users express skepticism about its effectiveness compared to clinical trials, with some suggesting it could be beneficial for those who cannot tolerate other treatments.

      community How do you use Fin or Dut and not bottom out your DHT ?

       1 upvotes 4 weeks ago
      A female user experiences severe side effects from topical finasteride and pumpkin seed oil for hair loss, leading to rapid hair thinning after stopping use. She seeks advice on tapering off treatments to manage hair sensitivity and maintain hair health.

      community RU58841 mixing with water solution

       5 upvotes 4 years ago
      RU58841 is being mixed with Minoxidil solution, but concerns arise about water causing instability. Mixing with water may lead to hydrolysis, potentially reducing effectiveness.

      community Long time Dutasteride users/experts please respond.

       8 upvotes 2 weeks ago
      Dutasteride and finasteride may affect sperm quality and fertility, with recommendations to stop use before trying to conceive. Dutasteride takes 4-6 months to clear from the system, while finasteride clears in about a week, but waiting longer is advised for optimal fertility.

      community Will Pp405 be the Ozempic of bald Guys

      in Research/Science  101 upvotes 7 months ago
      PP405 is being discussed as a potential hair loss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.

      community Is Stemoxydine not being made anymore???

       5 upvotes 11 months ago
      Stemoxydine, a hair loss treatment, is reportedly discontinued, with some users suggesting alternatives like a rebranded version with resveratrol that may enhance Minoxidil. Some users express dissatisfaction with the discontinuation and question the product's value.

      community Anyone only on RU or Pyrilutamide?

      in Research/Science 1 year ago
      The conversation discusses using RU58841 or Pyrilutamide for hair loss, with some users suggesting switching to more proven treatments like oral or topical finasteride. One user reports no progress with RU58841, finasteride, and minoxidil, and mentions experiencing regression.

      community Pelage PP405 Phase 2a completed.

       61 upvotes 7 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community Why is nobody talking about topical Spironolactone?

      in Chat  12 upvotes 5 months ago
      Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.

      community Stopped Fin and Min for 3 months.

      in Minoxidil  100 upvotes 2 months ago
      Stopping Minoxidil and Finasteride for three months led to significant hair shedding, prompting the user to resume treatment. The user experienced dry eyes as a side effect of Finasteride and noted that Minoxidil affected blood pressure.

      community New baldness drug boosts hair coverage by up to 86% in six months

       719 upvotes 3 months ago
      A new extended-release oral minoxidil formulation claims to improve hair growth by maintaining steady blood levels, reducing side effects like hypotension, and potentially benefiting female hair loss. However, it is not considered groundbreaking as it builds on existing minoxidil treatments, and its effectiveness compared to current doses is debated.

      community Can trichodynia ruin an exosome treatment?

      in Chat  1 upvotes 2 years ago
      The user has tried various hair loss treatments including topical minoxidil, oral finasteride, oral dutasteride, oral minoxidil, and exosome therapy, but none have been effective. They suspect trichodynia might be preventing these treatments from working.

      community Serioxyl / Stemoxydine no longer available

       4 upvotes 3 years ago
      Stemoxydine is no longer available on Amazon in the US, and users discuss alternatives for making topical finasteride. OP cannot use minoxidil due to side effects and seeks other solutions.

      community Musely s Exosome formulation looks interesting

       14 upvotes 1 year ago
      Exosomes, cetirizine, melatonin, latanoprost, and caffeine are discussed as potential hair loss treatments. There is skepticism about the effectiveness of exosomes, especially in topical form, but some users report positive results.

      community RU58841 has gotten rid of my acne

      in Product  1 upvotes 1 year ago
      RU58841, combined with 5% minoxidil, helped reduce acne and hair loss. Users discussed using RU58841 cream for acne and shared experiences with other treatments like finasteride and dutasteride.

      community Low cortisol it is due the fin

       7 upvotes 1 year ago
      The user has been taking 1mg finasteride daily for a year with no improvement in hair loss and reports low cortisol levels, sleep issues, and anxiety changes. The conversation includes discussions on the potential effects of finasteride on cortisol and neurosteroids, with suggestions to consult a doctor and consider other factors.

      community Does finasteride decrease free testosterone?

      in Research/Science  186 upvotes 1 year ago
      Finasteride may decrease free testosterone by increasing SHBG, potentially causing side effects like reduced libido and hormonal changes. Some find it effective for hair loss, while others experience negative effects.

      community Why is scalp DHT suppression lower than systemic?

      in Finasteride/Dutasteride  11 upvotes 1 year ago
      Dutasteride reduces DHT more effectively in hair follicles than finasteride, but some individuals still experience hair loss despite treatment. Combining oral and topical finasteride may improve results, and some users experiment with topical dutasteride despite uncertainties about its absorption.

      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 3 months ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community Are any of you using topical spironolactone ?

      in Treatment  4 upvotes 1 year ago
      The user is using topical dutasteride, minoxidil, and spironolactone for hair loss, with positive results after adding spironolactone. Another user takes oral spironolactone, dutasteride, and finasteride, noting decreased libido but no major side effects.

      community Does the effect of spironolactone on androgenetic alopecia really weaken over time?

       4 upvotes 1 year ago
      Spironolactone can remain effective for a long time in treating androgenetic alopecia, but it may not completely stop hair loss. Hair loss treatments like spironolactone, finasteride, and dutasteride slow down hair loss rather than cure it, and their effectiveness can vary based on individual response and the aggressiveness of the condition.