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      community It looks like Pelage are giving hints that PP405 is a game changer

      in Chat  239 upvotes 5 months ago
      PP405 is seen as a potential breakthrough for converting vellus hairs to terminal hairs, with users expressing both hope and skepticism. It is compared to treatments like minoxidil and finasteride, with discussions on side effects and marketing concerns.

      community 10 months of progress on oral fin and min

       18 upvotes 1 month ago
      The user experienced significant hair regrowth on the crown after 10 months using oral minoxidil, finasteride, and biotin, with initial side effects that settled over time. They are considering whether to increase the dosage or get a transplant for further improvement.

      community Treatment from July 2025 - Present

      in Is this regrowth?  17 upvotes 10 months ago
      The user is experiencing hair regrowth using 1mg oral finasteride daily, Minoxidil foam twice a day, and microneedling weekly with a 1.5mm needle. They are seeking feedback and suggestions to optimize their hair regrowth.

      community Why does finasteride stop working?

      in Finasteride/Dutasteride  26 upvotes 1 year ago
      Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.

      community Has anyone tried exosome treatment?

       8 upvotes 9 months ago
      Exosome treatment for hair loss, derived from umbilical cord stem cells, is being considered as an option before a hair transplant. Users discuss the need for ongoing maintenance and share experiences with different exosome sources, including plant-derived options.

      community Why don't Minoxidil regenerated hairs become terminal on the head?

      in Minoxidil  101 upvotes 1 year ago
      Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.

      community Here's the high school I attended. I graduated with a bottle of finasteride.

      in Satire  401 upvotes 2 years ago
      A user humorously shared that someone at their high school gave out finasteride pills, which introduced them to the drug for their receding hairline. The conversation also touched on the high school's location and appearance, with some users joking about their own hair loss and treatments like minoxidil and finasteride.

      community Musely s Exosome formulation looks interesting

       14 upvotes 1 year ago
      Exosomes, cetirizine, melatonin, latanoprost, and caffeine are discussed as potential hair loss treatments. There is skepticism about the effectiveness of exosomes, especially in topical form, but some users report positive results.

      community 21 Year Old- Progress on Oral Min and Fin

      in Update  6 upvotes 5 months ago
      A 21-year-old male experienced significant hair regrowth and thickening after eight months of using 2.5 mg oral minoxidil and 1 mg oral finasteride, along with keto shampoo and micro stamping. He reported no side effects and noted that improvements were most noticeable in months 7-8, particularly at the hairline and corners.

      community 75 days on Oral Min & Oral Fin Retrograde Alopecia

       64 upvotes 4 months ago
      A user shared their 75-day progress using oral minoxidil, finasteride, ketoconazole shampoo, and dermastamping for retrograde alopecia, reporting significant improvement and increased body hair without side effects. They also discussed quitting smoking and the potential correlation between early beard growth and male pattern baldness.

      community Rosemary out here changing lives for the better

      in Treatment  90 upvotes 2 years ago
      Rosemary oil is being used as an addition to minoxidil and finasteride for hair health, with mixed opinions on its effectiveness. Some users report positive results, while others see no benefit or experience adverse effects.

      community Bile Acid-Mediated DHT Dysregulation Hypothesis

      in Research/Science  13 upvotes 1 year ago
      Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

      community Lasering body hair off boosts scalp hair growth?

       4 upvotes 7 years ago
      Lasering off body hair does not boost scalp hair growth, as removing body hair does not redirect hair growth substances to the scalp. The idea that body hair uses up resources needed for scalp hair is incorrect, and treatments like finasteride are suggested for addressing hair loss.

      community Nutrafol backed by Science to reverse male balding?

      in Research/Science  1 upvotes 1 year ago
      Nutrafol helps improve hair thickness and hairline but may have potential health risks like liver damage and increased prostate cancer risk. The user plans to continue Nutrafol at a lower dosage while managing seborrheic dermatitis and considers future use of topical finasteride, minoxidil, rosemary oil, and microneedling.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 1 year ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community Is there anyone who tried this product?

       2 upvotes 2 years ago
      A user discussed trying a hair loss product containing 10% Minoxidil and 1% Finasteride, noting it dries quickly and smells of alcohol. Other users commented that 10% Minoxidil might cause more irritation without added benefits compared to 5%.

      community Help with female pattern baldness

       10 upvotes 2 years ago
      A user discusses their struggle with female pattern baldness, mentioning that Minoxidil helped initially but their hair health declined after stopping a specific diet. They seek advice on managing oily, brittle hair and mention using an egg yolk and olive oil mixture as a temporary solution.

      community my Body hair has stopped working

      in Finasteride/Dutasteride  44 upvotes 2 years ago
      A user on dutasteride for hair loss noticed hair regrowth on their head but a significant reduction in body hair growth. They plan to switch to finasteride and dutasteride and are considering testosterone replacement therapy but are concerned about its effects on hair growth.

      community Finasteride with high estradiol levels

       7 upvotes 2 years ago
      A 22-year-old with high estradiol levels is considering starting finasteride for hair loss. They have an upcoming endocrinologist appointment to discuss whether they should proceed with the treatment.

      community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

       15 upvotes 5 months ago
      A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

      community Unpopular Opinion: hair cloning kind of sucks as a potential future cure.

       27 upvotes 1 year ago
      Hair cloning is seen as a distant and potentially less relevant solution for hair loss due to its high cost, invasiveness, and the advancement of other treatments like Minoxidil and finasteride. Many believe that by the time hair cloning becomes viable, other less invasive and more effective treatments will be available.

      community 23m is this progress or not ….

      in Is this regrowth?  24 upvotes 11 months ago
      The user experienced hair regrowth using minoxidil and finasteride but reported scalp itching, possibly due to the liquid form of minoxidil. They also use ketoconazole shampoo to manage flakes, which they clarify are not dandruff.