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      community Thinking of making my own Breezula. Any advice?

      in Research/Science  6 upvotes 9 months ago
      OP is considering making a 5% topical Clascoterone (Breezula) for hair loss, as they use Minoxidil but can't use Finasteride due to side effects. They seek advice on creating the topical safely, possibly with help from a trained chemist.

      community What percentage of people getting sides from Fin do you think is actually due to Nocebo ?

      in Finasteride/Dutasteride  7 upvotes 4 weeks ago
      Many users believe the nocebo effect contributes to perceived side effects of finasteride, with some attributing libido changes to pre-existing conditions rather than the drug itself. While some report genuine side effects, others suggest these are overrepresented or imagined, emphasizing the importance of understanding one's baseline health before starting treatment.

      community Koshine 1% applied once or twice daily?

      in Research/Science  2 upvotes 1 year ago
      The conversation discusses the application frequency of a 1% Koshine solution for hair loss, with recommendations varying between once or twice daily. It is noted that the 1% solution is more effective than the 0.5% solution.

      community Has anyone seen the data on this 539% boost breakthrough?

       866 upvotes 6 months ago
      Topical Clascoterone showed a 539% improvement in hair count compared to placebo, but its effectiveness and safety are debated. Users compared it to minoxidil and finasteride, with mixed opinions on its potential release in 2026 or 2027.

      community How is PP405 looking compared to Minoxidil?

       20 upvotes 10 months ago
      PP405 is being compared to Minoxidil, with some suggesting it might be more effective since it's specifically designed for hair loss. Minoxidil was originally for blood pressure, and its hair growth effect is a side effect.

      community question people who let others influence them?

      in Chat  5 upvotes 1 month ago
      The conversation discusses the emotional impact of hair loss and the importance of taking personal responsibility for treatment decisions. The original poster ignored others' opinions and started using finasteride, expressing relief and frustration over external influences delaying treatment.

      community JXL082 is not PP405 and Everychem followed the wrong lead

       41 upvotes 1 year ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community It's probably RU58841, which is weak in adenosine.

       16 upvotes 2 years ago
      The conversation is about using adenosine, finasteride, and minoxidil for hair loss treatment. The user ordered a 0.75% adenosine solution and is currently using finasteride 1mg and minoxidil 5%.

      community How can you make your own PP405

      in Research/Science  2 upvotes 1 year ago
      People are discussing making their own PP405 for hair loss treatment using JLX069 and DMSO. There is skepticism about the safety and effectiveness of this homemade solution, with some users expressing concerns about potential risks.

      community A Nuanced Look at Microdosing Topical Finasteride

       86 upvotes 2 years ago
      The conversation discusses using a low dose of topical finasteride to achieve hair benefits with minimal systemic exposure. Users share experiences and opinions on dosing, systemic buildup, and side effects of both topical and oral finasteride.

      community Any good experiences with Alfatradiol ?

       4 upvotes 6 years ago
      Alfatradiol is discussed as a weak 5ARI and estrogen, not as effective as minoxidil, RU58841, or CB-03-01, but a safe alternative for those who can't use finasteride. Users express frustration over the lack of strong FDA-approved topical antiandrogens for hair loss.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

       11 upvotes 2 years ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community Anyone in the discord server for pp405 research?

      in Chat  5 upvotes 1 year ago
      The conversation is about users trying to regain access to a Discord server related to pp405 research, with differing opinions on the effectiveness of pp405 for hair loss. Specific treatments like Minoxidil, finasteride, and RU58841 are not mentioned in the conversation.

      community How are people getting DUT so easily?

      in Finasteride/Dutasteride  15 upvotes 1 year ago
      Dutasteride is hard to get in Europe due to prescription rules, leading some to consider online pharmacies or travel. Users discuss alternatives like private doctors and compare it to finasteride, expressing concerns about side effects and effectiveness.

      community Inconsistent 0.1%/5% topical fin/min for last 9 months

      in Progress Pictures  7 upvotes 8 months ago
      The user has been inconsistently using a 0.1% finasteride and 5% minoxidil topical treatment for hair loss over the past nine months, along with 1% Nizoral once a week. They aim to improve consistency in their treatment this year and report no side effects.

      community ultimate nuclear stack? need more suggestions bruhh

      in Technology  2 upvotes 1 year ago
      The conversation discusses an extensive hair loss treatment regimen including dutasteride, GT20029, RU58841, pyrilutamide, minoxidil, microneedling, ketoconazole shampoo, and experimental compounds. The user humorously describes their approach as a comprehensive strategy to combat hair loss while maintaining hair growth.

      community Let’s talk about dosing azelaic acid

       4 upvotes 6 years ago
      The conversation discusses using minoxidil 5% with azelaic acid for hair loss treatment. Users share tips on sourcing and mixing azelaic acid with minoxidil.

      community The revolution Pp405 ...........

       4 upvotes 11 months ago
      The conversation discusses hair regrowth treatments, specifically using Minoxidil, finasteride, and RU58841. The focus is on whether these treatments are effective for hair regrowth.

      community Dr Couto consultation and finasteride

       6 upvotes 3 years ago
      Dr. Couto recommends taking finasteride in the morning to align with peak testosterone and DHT production for better effectiveness. Oral minoxidil is acknowledged as better than topical, but the focus is on stabilizing hair loss with finasteride first.

      community Jason Sorgi - Boston Hair Restoration- Crown MicroFUE (full detailed breakdown).

       383 upvotes 6 months ago
      A user shared their positive experience with a crown MicroFUE hair transplant at Boston Hair Restoration, highlighting the smooth procedure, minimal pain, and significant growth over 12 months. They used oral minoxidil, finasteride (transitioning to dutasteride), PRP sessions, and a LaserCap, achieving excellent results and full confidence.

      community Topical min once a day and 0,5mg dut EOD

      in Progress Pictures  131 upvotes 9 months ago
      The user experienced significant hair regrowth after 7 months using topical minoxidil once a day and 0.5mg dutasteride every other day, with noticeable results in the last two to three months. They reported no side effects and did not use dermarolling.

      community It's so over. Im beyond cooked

      in Update 10 months ago
      The user is experiencing hair loss despite using Dutasteride and plans to try RU58841, considering adding Oral Minoxidil. They express frustration with diffuse thinning and seek advice on managing hair loss.

      community ACV Shampoo Bar

       13 upvotes 9 years ago
      The conversation discusses using an apple cider vinegar shampoo bar as an alternative to Nizoral 2% ketoconazole due to excessive shedding. Users also mention starting minoxidil and considering finasteride, while exploring natural shampoo options to reduce scalp irritation and hair loss.

      community Anyone have any experience with these SoCal Hair Surgeons?

      1 month ago
      The conversation is about choosing a local hair transplant surgeon in Southern California, with specific mentions of Dr. Ken Williams, Dr. Varona, Dr. Sean Behnam, Dr. Amir Yazdan, and Dr. Nader. The user prefers not to consider options outside the U.S. due to safety concerns and cost issues with Dr. Mohebi.