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      community Update for PP405 - phase 2b underway

       122 upvotes 1 year ago
      PP405 is advancing to Phase 2b trials, showing promise from Phase 2a. It may be available in 3-6 years, with trials using a topical gel.

      community Koshinemall is official site, confirmed

      in Research/Science  3 upvotes 2 years ago
      A user confirmed that koshinemall.com is the official site for buying Pyrilutamide after contacting Kintor directly. They expressed initial skepticism due to the website's quality and phone number requirement.

      community Pyrilutamide / KX-826 / Koshine — has it been working for you?

       10 upvotes 1 year ago
      Pyrilutamide/KX-826 is being discussed for its effectiveness in hair regrowth, with some users reporting positive results, especially in early hair loss cases. Users have combined it with treatments like Minoxidil, and some experienced initial shedding before seeing regrowth.

      community Kintor KX-826 Discounts (and is the 0.9% more effective)?

       5 upvotes 9 months ago
      Kintor KX-826, a hair loss treatment, is being discussed for its pricing and effectiveness, with a focus on whether the 0.9% concentration is more effective than the 0.5%. Users are seeking cheaper purchasing options.

      community Ru58841 20mg….making my own solution

      in Treatment  1 upvotes 1 year ago
      The conversation is about making a 20mg/ml RU58841 solution for hair loss treatment using ethanol and propylene glycol. The user receives advice on calculating the correct amount of RU58841 powder needed.

      community PP405 Might Be the Closest We Have to a Upcoming Cure

      in Technology  237 upvotes 1 year ago
      PP405 is considered a promising potential cure for hair loss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.

      community Chinese source for pyrilutamide or ru8841 ?

       3 upvotes 11 months ago
      The conversation is about finding a reliable Chinese source for pyrilutamide or RU58841, ideally with a third-party Certificate of Analysis from Janoshik Analytical. The user is seeking recommendations for these hair loss treatments.

      community Ru delivery and heat outside .

      in Treatment  1 upvotes 1 year ago
      The conversation discusses concerns about the effectiveness of RU58841 due to high temperatures during delivery. A user reassures that the heat will not affect its efficacy.

      community I'm losing it with RU58841 lol. Any fellow RU user help is appreciated.

       8 upvotes 2 months ago
      The user is struggling with the high cost of RU58841 and is seeking cheaper bulk sources, considering options like Carolina Chemical. Other users discuss alternative treatments like finasteride, minoxidil, and dutasteride, with mixed experiences on effectiveness.

      community Canadians, is CBSA seizing anageninc RU58841 powder?

       1 upvotes 1 month ago
      The conversation discusses the successful receipt of RU58841 powder in Canada, with no reported issues from a user in British Columbia. The original poster is curious about potential seizures by CBSA but hasn't purchased it yet.

      community A warning to anyone considering 3rd party sourcing PP405 or its analogs

       30 upvotes 5 months ago
      Be cautious when sourcing PP405 or its analogs from third-party suppliers due to potential safety risks and lack of regulatory approval. The conversation highlights concerns about counterfeit products and the absence of reliable testing, making it risky to use such treatments.

      community Won’t pp405 and gt20029 be patented and be almost unreasonably expensive

       29 upvotes 1 year ago
      Concerns about the potential high cost of new hair loss treatments, pp405 and gt20029, were discussed, with some users willing to pay a premium if they are effective. Alternatives like finasteride and minoxidil are mentioned as current, more affordable options, and there is speculation about future generic versions and black market availability.

      community is there any news about pp405 please

       10 upvotes 1 year ago
      There is no new information on pp405, with data collection expected to finish by the end of 2025. Users are discussing the timeline for data analysis and completion of Pelage Pharmaceuticals' phase 2 study.

      community I hope ET-02 or PP405 will be released in the next 4-5 years

       18 upvotes 1 year ago
      PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

      community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

       7 upvotes 5 months ago
      AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

      community 2dDR experiment. Seems to be doing something.

       11 upvotes 1 month ago
      A user shared their experience using 2-deoxy-D-ribose (2dDR) for hair regrowth, noting early positive results without side effects, alongside their long-term use of minoxidil and finasteride. They mentioned 2dDR's potential effectiveness in boosting blood flow to hair follicles and its availability online.

      community Everyday shampoo option?

       3 upvotes 7 years ago
      The conversation is about finding an affordable, sulfate-free shampoo for regular use alongside Nizoral to improve scalp health affected by minoxidil. Suggestions include NOT YOUR MOTHER'S Naturals Coconut Milk & African Marula Tree Oil High Moisture Shampoo and Mane and Tail Hair & Body Shampoo.

      community Best brand of hair fibres to buy?

       6 upvotes 6 days ago
      A user in the UK is seeking recommendations for hair fibers. Nanogen is suggested as a good brand.

      community Wrap it up everyone. CB-03-01 is another failed treatment

       79 upvotes 1 year ago
      CB-03-01 is considered a failed treatment for hair loss, with future hopes pinned on PP-405 and GT-20029, expected by 2030. Alternatives like hair transplants and SMP are discussed, while some users express frustration over the slow progress of treatments like Breezula.

      community Nizoral and what other shampoo?

      in Ketoconazole  6 upvotes 8 months ago
      The conversation is about choosing a second shampoo to use alongside Nizoral for hair loss treatment. Suggestions include Nioxin, baby shampoo, Lipogaine, and Revita, with some users recommending letting the shampoo sit for a few minutes before rinsing.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 10 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Koshine 1% applied once or twice daily?

      in Research/Science  2 upvotes 1 year ago
      The conversation discusses the application frequency of a 1% Koshine solution for hair loss, with recommendations varying between once or twice daily. It is noted that the 1% solution is more effective than the 0.5% solution.

      community Who here is on Koshine 826 (Pyrilutamide) and does it cause shedding?

      in Treatment  12 upvotes 2 years ago
      Koshine 826 (Pyrilutamide) is being used by several users to address hair loss, with mixed results on shedding and side effects. Some users report reduced shedding and no side effects, while others experience increased shedding and potential issues with libido and erectile dysfunction.

      community Where to buy RU58441 in Germany

       6 upvotes 4 months ago
      The conversation is about finding a source to buy RU58841 in Germany, specifically looking for a PG-free option. Users suggest buying powder and mixing it themselves, with one user recommending a specific website.