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      community Megadosing Koshine826(Pyrilutamide), my Plan.

      in Treatment  1 upvotes 3 months ago
      The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.

      community Just find a cure already, I am totally done

      in Chat  161 upvotes 4 months ago
      The conversation is about hair loss treatments, with users recommending finasteride and minoxidil as effective solutions. Some users report side effects, but overall, the consensus is to use these treatments rather than waiting for a cure.

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

      in Finasteride/Dutasteride  26 upvotes 4 months ago
      The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 5 months ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

      community Topical Dutasteride 0.025% 2ml once a week

      in Treatment  9 upvotes 5 months ago
      A user discusses using topical dutasteride 0.025% once a week for hair maintenance, alongside fortified minoxidil, RU58841, and Reviv Hair Serum. They seek feedback on the effectiveness of this regimen.

      community 22M loosing ground - 1MG fin + 2% Keto Shampoo

      in Is this regrowth?  40 upvotes 5 months ago
      A 22-year-old using finasteride and 2% ketoconazole shampoo for hair loss sees mixed results after three months, with some improvement at the crown but worsening at the temples. Suggestions include waiting 6-12 months, considering dutasteride, adding minoxidil, microneedling, caffeine tonic, and retinol.

      community Topical Dutasteride. Does it work?

      in Finasteride/Dutasteride  13 upvotes 6 months ago
      Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

      community How does dutasteride regrowth work?

      in Finasteride/Dutasteride  6 upvotes 7 months ago
      A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

      community How is there still no consensus on Topical Dutasteride in 2024?

      in Finasteride/Dutasteride  147 upvotes 7 months ago
      The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

      community Just started RU a month ago after being on fin and min for almost 3 years. Progress so far: My temples were pretty bare before this. Really hoping at least some of these become terminal.

      in Is this regrowth?  393 upvotes 8 months ago
      A user started using RU58841 a month ago after using finasteride and minoxidil for nearly three years, hoping for hair regrowth at the temples. Other users suggest vitamin B supplements and microneedling to improve hair thickness, and one mentions the possibility of a hair transplant for the temples.

      community Will my liver get destroyed long term on this stack ??

      in Chat  15 upvotes 10 months ago
      A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  140 upvotes 10 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community TDM-105795 phase 2 results are in!

      in Research/Science  28 upvotes 10 months ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community Topical Finasteride strength discussion

      in Research/Science  65 upvotes 10 months ago
      The conversation discusses the effectiveness of different concentrations and dosages of topical finasteride on scalp and serum DHT levels, comparing it to oral finasteride and noting the side effects seem to be fewer at lower dosages. Participants shared experiences and referenced a chart indicating similar scalp DHT reduction with 0.025% topical finasteride as with 1mg oral finasteride, but with fewer side effects.

      community Why nobody uses 0.25% (2.5mg/ml)?

      in Treatment  66 upvotes 11 months ago
      The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

      community 16month progress on crazy stack

      in Finasteride/Dutasteride  8 upvotes 1 year ago
      The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.

      community Update: 16 months deep - big 3

      in Progress Pictures  407 upvotes 1 year ago
      The user has seen positive results after 16 months of using topical Finasteride/Minoxidil, microneedling weekly, and Tretinoin for hair loss. There are no reported side effects, and the user advises that the effectiveness of microneedling depends on the pressure applied.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 1 year ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.