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      community 4 months min/dut/needling Norwood 6

      in Progress Pictures  13 upvotes 9 months ago
      The user is using oral Minoxidil, oral Dutasteride, microneedling, and RU58841 for hair loss, noticing slow progress with small hairs appearing. They are inconsistent with microneedling frequency, sometimes doing it weekly or skipping weeks.

      community How do I layer multiple treatments?

      in Treatment  2 upvotes 2 years ago
      The user asks about the order and compatibility of using topical minoxidil, stemoxydine, The Ordinary natural moisturizing factors + HA for scalp, RU58841, and Nioxin system 2 leave-in treatment. They seek advice on layering these hair loss treatments.

      community Welp - pp405 conference showed nothing

       81 upvotes 5 months ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community My microneedling journey (no min, fin, etc)

      in Microneedling  210 upvotes 1 year ago
      The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

       213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community 2 year update: fin, min, and microneedling

       85 upvotes 5 months ago
      The user shared a two-year update on hair loss treatment using oral minoxidil, finasteride, and microneedling, noting significant progress after starting oral treatments and microneedling. They began treatment in early 2023 after noticing hair loss in late 2021.

      community Painkillers May Block Minoxidil

       12 upvotes 1 year ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community anyone ever try msm for hair growth?

       4 upvotes 3 years ago
      MSM supplements are discussed for hair growth, with mixed opinions on their effectiveness. Some users combine MSM with treatments like finasteride and minoxidil, while others report no noticeable benefits.

      community [M29] 13 months fin, 4 months topical min

       5 upvotes 1 year ago
      A 29-year-old male reports using 1.25mg finasteride daily and applying minoxidil twice daily to the temples for hair loss, noting modest progress over 13 months. He attributes rapid hair loss onset to creatine use and is considering a hair transplant in the future.

      community 8 month minoxidil and finasteride update.

       237 upvotes 2 years ago
      The user experienced significant hair regrowth and increased confidence after 8 months of using 1mg finasteride daily and 6% topical minoxidil once a day. They reported no side effects and are considering microneedling and possibly testosterone replacement therapy if needed.

      community Who else is looking forward to full phase 2 results of PP405?

      in Chat  59 upvotes 7 months ago
      PP405 is a potential hair loss treatment showing promise, especially for men with severe balding. Some are hopeful it will be a game-changer for those who cannot tolerate finasteride or minoxidil, despite skepticism about the outcomes.

      community Why PP405 may not be dead just yet

       1 upvotes 1 month ago
      PP405 shows promise in reactivating dormant hair follicles, with early trials indicating some success, but it is not yet a proven treatment for hair loss. Users are advised to be cautious with unverified versions, and further research is needed to confirm its effectiveness compared to treatments like minoxidil and finasteride.

      community M(23) 5 months of using Fin and Min

       69 upvotes 4 months ago
      A 23-year-old has been using finasteride every other day and topical minoxidil daily for five months to address hair thinning, with plans to resume dermarolling. They experienced minimal shedding and are considering switching to daily finasteride for better results.

      community Progress experience small tips

      in Progress Pictures  193 upvotes 1 month ago
      The user shared their hair regrowth progress using topical minoxidil, microneedling, and finasteride. They experienced significant improvement initially, switched from liquid to foam minoxidil, disliked the foam, and returned to liquid minoxidil.

      community New York Magazine article - the Great Unbalding

       48 upvotes 1 year ago
      PP405, a potential treatment for male pattern baldness, shows promise with some participants experiencing hair regrowth in early trials. However, it is not yet considered a cure and may be used alongside existing treatments like minoxidil and finasteride.

      community Few questions about my futur treatment

      in Treatment  3 upvotes 2 years ago
      The user, who experienced hair loss at the temples due to psoriasis at 17, is now 21 and considering treatment options. They are inquiring about using minoxidil once a day, whether non-AGA hair loss will persist after stopping minoxidil, and if alternative remedies like Detumescence therapy, rosemary and peppermint oils, and microneedling could be sufficient.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

       34 upvotes 8 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community 5 months no fin or min just copper peptides and nad+

       4 upvotes 7 months ago
      The conversation discusses hair regrowth progress using copper peptides and NAD+ without finasteride or minoxidil. Users suggest comparing wet and dry hair photos for better assessment.

      community 18mo progress - topical fin/min + oral min/dut

      in Progress Pictures  91 upvotes 1 year ago
      The user experienced significant hair regrowth using topical finasteride/minoxidil and oral minoxidil/dutasteride, with some mild side effects that diminished over time. They plan to add microneedling to their regimen and have seen hair shedding cycles every six months, followed by thicker regrowth.

      community Dear tressless, i have a question for you.

      in Technology  452 upvotes 5 months ago
      Minoxidil and finasteride are discussed for hair loss, with concerns about minoxidil's heart-related side effects. New treatments like PP405 are met with skepticism, often humorously noted as always being "five years away."

      community 3 months in on 1mg oral fin and 5% topical min twice daily

       18 upvotes 1 month ago
      The user has made significant hair growth progress in 3 months using 1mg oral finasteride and 5% topical minoxidil twice daily, with plans to start 1.25mg oral minoxidil. The user is considering a hair transplant in 1-2 years and is cautious about using a dermastamp to avoid scar tissue.

      community 6 months progress topical min/fin (19)

       96 upvotes 1 year ago
      The user is using a treatment of topical minoxidil 7% and finasteride 0.1% twice daily, along with a low-level laser therapy cap, biotin, and collagen supplements, and is seeing good progress on the hairline and temples but not the midscalp. They experienced initial shedding, saw results by month three, and are happy with the progress, though some users express concern about using finasteride at a young age.

      community Can i maintain Min progress with Fin/micro needling only ?

       4 upvotes 2 years ago
      The user experienced serious hair loss and started using finasteride, minoxidil, microneedling, and argan/rosemary oil. They are asking if they can maintain hair regrowth by stopping minoxidil and continuing only with finasteride and microneedling.

      community PP405 - A True Breakthrough or Another Disappointment?

       34 upvotes 1 year ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community 8 months on fin + min this are the results so far

       7 upvotes 1 week ago
      A 19-year-old has been using oral finasteride and topical minoxidil for 8 months with positive results and no side effects. The user believes they would have progressed to Norwood 4 without the medication.

      community 4 month closeup hairline progress on topical min and fin

      in Is this regrowth?  6 upvotes 2 years ago
      The user reports using topical minoxidil 6% and finasteride 0.05% once daily, along with microneedling, vitamins, biotin, and nizoral shampoo. They recently increased minoxidil and finasteride to twice daily and feel their hair is thicker but are unsure about regrowth.