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      community Anyone tried CB-03-01?does it work ?

      in Research/Science  2 upvotes 1 year ago
      CB-03-01, also known as Breezula, is being considered as an alternative to DHT blockers for hair loss. Users are discussing its effectiveness, potential regrowth, side effects like scalp irritation, and hormonal impacts.

      community 35M, huge improvement, microneedling for the win

       33 upvotes 9 months ago
      A 35-year-old male experienced significant hair improvement using microneedling, finasteride, minoxidil, and keto shampoo. He adjusted his microneedling routine for better results.

      community 1 Month RU58841 + Minoxidil + Weekly microneedle

      in Minoxidil  1 upvotes 8 months ago
      The user is using RU58841, Minoxidil, and weekly microneedling for hair loss, having stopped finasteride due to side effects like low libido and depression. They are considering dutasteride as an alternative but are cautious due to past experiences with DHT blockers.

      community RU-58841 appears to not be soluble in common Minoxidil solutions

       7 upvotes 11 months ago
      RU-58841 does not dissolve well in common Minoxidil solutions due to water content, requiring a 70/30 ethanol/propylene glycol mix. Users report using separate solutions for RU-58841 and finasteride/Minoxidil for better results.

      community Anyone who used RU58841 without fin/dut?

      in Product  1 upvotes 1 year ago
      RU58841 was used by some for hair loss, but concerns about side effects like gynecomastia and safety were raised. Alternatives like finasteride, minoxidil, pyrilutamide, and alfatradiol were discussed, with some users reporting better experiences with these treatments.

      community Lyphar Biotech. China source for RU58841

      in Research/Science  1 upvotes 7 months ago
      The conversation discusses the safety and trustworthiness of ordering RU58841 from Lyphar Biotech in China, with a focus on pricing and reliability. The user is seeking advice on whether to proceed with the purchase or consider alternative sources.

      community My dad says this is “a mircule”

       513 upvotes 1 year ago
      A 31-year-old user experienced hair regrowth and no side effects after switching from finasteride to dutasteride and using minoxidil foam daily. They reported improved hair retention and shared their treatment routine, including a prescription for dutasteride and the use of minoxidil, while humorously discussing side effects and personal experiences.

      community M35 diffuse thinning, sudden realization after collaging old pic

       11 upvotes 6 days ago
      The user experienced hair regrowth after starting finasteride in September 2025 and topical minoxidil in December 2025, despite setbacks from using tretinoin gel. Their current treatment includes dutasteride, finasteride, topical minoxidil, and dermastamping.

      community Black market pp405? Title title

      in Treatment  8 upvotes 8 months ago
      PP405 is likely fake, and JXL069 is an unrefined prototype with unknown side effects. It's advised to wait for the official PP405 release.

      community My summation of PP405 - looks promising

       210 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community SUBE3 for sale in the gray market?

       5 upvotes 1 year ago
      SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

      community How would you react if PP405 isn't successful in phase 3 trials?

      in Chat  23 upvotes 9 months ago
      People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

      community 23M 9 months (dut + minox + prp)

       169 upvotes 11 months ago
      A 23-year-old male experienced significant hair improvement over 9 months using dutasteride, minoxidil, finasteride, PRP, and red light therapy, with no side effects. He plans to continue treatment for 6 more months before deciding on a hair transplant.

      community Gray market sources to get gt20029 or pp405?

      in Product  2 upvotes 1 year ago
      The conversation is about sourcing gray market compounds, gt20029 and pp405, for hair loss treatment. The user is interested in these compounds despite their unproven status and potential risks.

      community Minoxidil experiment on single hair follicle

       1689 upvotes 1 year ago
      Minoxidil was applied to a single miniaturized hair follicle over four months, resulting in less miniaturization but not yet terminal growth. The user used a 5% minoxidil solution, specifically the Regaine brand, and observed changes using a handheld WiFi microscope.

      community P-1075: a BETTER version of Minoxidil

      11 months ago
      P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

       3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community 28M 5MG MIN 0.5MG DUT - CROWN FILLING IN

       381 upvotes 4 months ago
      A 28-year-old male reported significant hair regrowth using 5mg minoxidil and 0.5mg dutasteride over five months, with occasional ketoconazole use. Users discussed side effects like stuffy nose and low libido, and shared experiences with different hair loss treatments.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

       4 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community Possible explaination for Finasteride Reflex Hyperandrogenicity

       6 upvotes 4 years ago
      The user has been using finasteride and minoxidil for hair loss but experienced worsening temple recession. They suspect they might be more sensitive to testosterone and are considering trying RU58841 or CB 03 01 as additional treatments.

      community M27: month 3 of 5mg oral minoxidil and 0.5mg oral finasteride

      in Progress Pictures  349 upvotes 1 year ago
      A user shared progress pictures after three months of using 5mg oral minoxidil and 0.5mg oral finasteride, showing significant hair regrowth following a hair transplant. Other users praised the results, discussed similar experiences, and expressed interest in trying oral minoxidil.