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      community 14 months - 1mg fin & 5% topical minoxidil results

      in Progress Pictures  452 upvotes 4 months ago
      Significant hair regrowth was achieved using 1mg finasteride and 5% topical minoxidil over 14 months, with only initial shedding and mild scalp irritation as side effects. Consistency and early treatment are recommended for optimal results.

      community Just 3 Months Fin/Min, It's working!!! [30M]

       214 upvotes 4 months ago
      A 30-year-old man saw improved hair density and texture after three months using Minoxidil, Finasteride, and ketoconazole shampoo, despite initial side effects. He experienced increased body hair and libido and is satisfied with the results despite the high cost in Turkey.

      community Should I risk changing to Dutasteride?

      in Finasteride/Dutasteride  10 upvotes 1 year ago
      The user is considering switching from Finasteride to Dutasteride for better hair regrowth, despite concerns about potential shedding and side effects. Opinions vary, with some suggesting the switch for stronger results and others advising caution due to possible side effects and the importance of consulting a doctor.

      community Article of all potential future cures

       25 upvotes 1 year ago
      Ritlecitinib and PP405 show promise for hair regrowth. Diagnosing the cause of hair loss is crucial before treatment.

      community Oral Min is much better than topical

      in Minoxidil  182 upvotes 1 year ago
      Oral minoxidil is seen as more effective and convenient than topical minoxidil for hair regrowth, but it may cause heart-related risks. Users often combine it with finasteride or dutasteride, though some prefer topical treatments due to safety concerns.

      community Stop wasting your time with BS products

      in Treatment  413 upvotes 1 year ago
      Effective treatments for hair loss include finasteride, dutasteride, RU58841, and minoxidil. Starting treatment early is important, and users discuss different brands, forms, and side effects.

      community What 3 months without fin& min does😔

      in Progress Pictures  261 upvotes 1 year ago
      Stopping minoxidil and finasteride for three months caused significant hair loss. The user resumed treatment with 2.5mg oral minoxidil and 0.6mg finasteride and plans to update on progress in three months.

      community Are they going to Ban Finasteride in the EU ?

      in Finasteride/Dutasteride  68 upvotes 1 year ago
      There is concern about a potential ban on finasteride in the EU, but many believe it is unlikely unless serious side effects are found. Users rely on finasteride for hair loss and other health benefits, and a petition has been created to oppose any restrictions.

      community Expectations control for SCUBE3

       20 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community Since there is so much hype for cosmeRNA and HMI-115...

       44 upvotes 3 years ago
      Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

      community MicroRNA science breakthrough? Softening stem cells

       6 upvotes 3 years ago
      A potential breakthrough in hair loss treatment involves softening hair follicle stem cells, but its effectiveness in humans is uncertain. Users express skepticism, noting past successes in mice that haven't translated to human treatments.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community Can HMI-115 reverse miniaturization?

       12 upvotes 3 years ago
      HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

      community Amplifica and AMP-303 clinical phase 1

       9 upvotes 2 years ago
      Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.

      community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

       110 upvotes 2 years ago
      Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

      community IGF-1 and Peptides? Miracle molecule waiting to be found

       10 upvotes 1 year ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

       13 upvotes 9 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Keratin microspheres - breakthrough

       14 upvotes 2 years ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.