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      community Dermastamping — do you use hyaluronic acid as lubricant?

       3 upvotes 1 year ago
      The conversation discusses using high molecular weight hyaluronic acid after microneedling to form a protective barrier, though it's considered expensive and offers marginal improvement. Users share experiences with different microneedling tools like derma rollers, dermastamps, and Dr. Pen, with some opting not to use any products on the scalp.

      community Koshinemall is official site, confirmed

      in Research/Science  3 upvotes 2 years ago
      A user confirmed that koshinemall.com is the official site for buying Pyrilutamide after contacting Kintor directly. They expressed initial skepticism due to the website's quality and phone number requirement.

      community Low Estradiol while on 1mg Fin, what should I do?

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      A user on 1mg finasteride for a year has low estradiol levels but no significant symptoms, and others suggest monitoring without immediate concern. Some users discuss potential effects of low estrogen, like low libido, but the user reports no erectile dysfunction.

      community MPB or "Maturing Hairline"? [22]

       5 upvotes 11 years ago
      The conversation discusses concerns about a receding hairline potentially due to increased DHT from creatine use, with suggestions to try Rogaine. The user plans to seek a professional opinion and notes a family history of early baldness.

      community Oral Minoxidil - The Hyper-Responder Concept

       4 upvotes 10 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community PP405 (Everychem 3HP) users - assemble and share your updates!!

      in Chat  44 upvotes 4 months ago
      Users discussed experiences with Everychem's solution similar to PP405 for hair loss, noting some positive results like increased hair thickness and new growth. There was skepticism about the product's legitimacy and safety, with some users reporting early signs of effectiveness and others expressing concerns about the lack of evidence and safety profiles.

      community 3 month progress on 0.5mg fin only - I think it’s saving me.

      in Progress Pictures  77 upvotes 1 year ago
      A 23-year-old male shares his positive progress using 0.5mg finasteride for hair loss, noting initial side effects like sore nipples that resolved after adjusting the dosage. Other users discuss their experiences with finasteride, including effects on libido and the trade-offs of using the medication.

      community questions regarding topical finasteride

      in Finasteride  4 upvotes 7 years ago
      The conversation discusses the potential effectiveness and risks of using topical finasteride for hair loss, with considerations about using DMSO as a vehicle for application. Concerns are raised about DMSO's safety, absorption issues, and the systemic effects of topical finasteride.

      community Ranking of all the topical anti androgens in terms of effectivness?

       5 upvotes 3 years ago
      There is no reliable ranking for the effectiveness of topical anti-androgens like Fluridil, RU58841, and Pyrilutamide, with limited studies available. Some users suggest Pyrilutamide may be promising based on ongoing trials, while Fluridil combined with finasteride has shown positive results for some individuals.

      community ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data

       17 upvotes 8 months ago
      ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.

      community thoughts on dutasteride mesotherapy?

       3 upvotes 3 years ago
      Dutasteride mesotherapy for hair loss, with the user reporting minimal pain during the procedure. Other users mention success stories and inquire about additional treatments.

      community My Estradiol Level on Finasteride

       18 upvotes 1 year ago
      Finasteride has no effect on the user's estradiol levels, and body fat may influence aromatization. The user is on testosterone replacement therapy and uses everyday injections to manage high RBC count, with plans to measure DHT, DHEA-S, and pregnenolone levels.

      community Has anyone had success with lipodermal solution?

       1 upvotes 1 year ago
      The conversation discusses using a lipodermal solution for hair loss, with concerns about side effects from multiple active ingredients. Users mention experiences with minoxidil, finasteride, and dutasteride, noting side effects like brain fog and sexual issues.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  210 upvotes 1 year ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Homemade fin - solubilization issue

       1 upvotes 3 years ago
      The user is attempting to create a topical finasteride solution by mixing crushed finasteride pills with minoxidil but is facing solubility issues. They are unsure if the finasteride has dissolved properly and are seeking advice on whether it is safe to use and if there is a solution to the problem.

      community Has Anyone Heard About Ethossomal Finasteride? 6x Finasteride Delivery in Hair Folicule?

       36 upvotes 3 years ago
      A user is considering switching from oral to topical finasteride to reduce systemic DHT impact and is exploring ethossomal finasteride for better skin penetration and potential hair regrowth. They found ethossomal finasteride in Brazil and are seeking opinions on its effectiveness compared to other topical delivery methods.

      community Tretinoin buffering before minoxidil

       7 upvotes 2 months ago
      Buffering tretinoin with a moisturizer before applying minoxidil may help with itchy dandruff. Exfoliating the scalp with fingertips and using olive oil or conditioner can remove product buildup.

      community Pre-mixed RU58841 in the KB solution vs PG solution?

       4 upvotes 5 years ago
      Choosing between KB and PG solutions for applying RU58841, considering factors like scalp oiliness and absorption. Some users prefer KB for being gentler, while others use PG and recommend washing hair before application for better results.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 6 months ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community Why is nobody talking about the new study results for Pyrilutamide??

       53 upvotes 1 year ago
      Pyrilutamide shows promising hair growth results, but skepticism exists due to potential biases and lack of blinding in the study. Concerns about side effects and legitimacy of the product persist, with comparisons to finasteride and discussions on post-finasteride syndrome.

      community Consenus on Kx-826/pyrilutamide vs ru58841

       11 upvotes 1 week ago
      KX-826 is considered effective for hair maintenance, with better safety research than RU58841, but lacks positive anecdotes. RU58841 is seen as potentially stronger, but concerns exist about systemic effects; combining anti-androgens with 5AR inhibitors is suggested for better results.