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      community is anyone using ru58841 against acne?

      in Technology  2 upvotes 3 weeks ago
      RU58841 is discussed as a potential treatment for acne and hair loss, with users debating its effectiveness and safety compared to other treatments like finasteride, minoxidil, and dutasteride. Concerns about RU58841's side effects and lack of clinical trials are raised, while some users share their personal experiences and routines involving RU58841 for hair loss.

      community What do you think about pyrilutamide?

      in Product  5 upvotes 1 month ago
      Pyrilutamide is being discussed as a potential hair loss treatment, but opinions are mixed, with some users skeptical about its effectiveness and the company's credibility. Some users report combining pyrilutamide with other treatments like dutasteride and microneedling, noting improvements, while others remain doubtful.

      community PP405 Might Be the Closest We Have to a Upcoming Cure

      in Technology  237 upvotes 2 months ago
      PP405 is considered a promising potential cure for hair loss, with phase 2 trial results expected in February 2025. Hair cloning is also discussed as a potential ultimate solution, despite significant scientific challenges.

      community The Cure isn't 5 years away; it's already here.

      in Research/Science  995 upvotes 2 months ago
      PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

      community Forget about new treatments (just temporarily for the sake of argument). What do you think is the likelihood of existing treatments being improved in the next few years?

      in Research/Science  1 upvotes 2 months ago
      Existing hair loss treatments like oral finasteride, topical minoxidil, and hair transplants are still the main options, with some improvements in affordability and techniques. There is hope for enhancing these treatments, but new effective solutions are unlikely in the near future.

      community Pyrilutamide from RUdirect, legit or fake?

      in Product  5 upvotes 2 months ago
      Pyrilutamide from RUdirect is discussed, with users sharing experiences and alternative sources like Koshinemall. Users mention using treatments like minoxidil, RU58841, and dutasteride for hair loss.

      community In God We Trust, Topical Fin/Min with existing ADHD issues

      in Chat  19 upvotes 3 months ago
      A 27-year-old male with ADHD is experiencing hair thinning and is starting a treatment with topical finasteride (0.025%) and minoxidil (5%). He is addressing high prolactin levels and low vitamin D, while managing side effects from ADHD medication.

      community Any updates or news on Gt20029?

      in Chat  8 upvotes 3 months ago
      There are no updates on GT20029, and concerns about its safety and effectiveness remain. The phase III trial has not started, and there are no new studies or data releases.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 3 months ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

      community 3 Months Topical Fin/Min/Tret Spray

      in Is this regrowth?  47 upvotes 4 months ago
      A 28-year-old male experienced hair regrowth using a topical spray containing minoxidil, finasteride, and tretinoin, along with occasional microneedling, after stopping oral finasteride due to side effects. He is pleased with the progress after three months and plans to continue using the spray.

      community Pyrilutamide and RU alternatives?

      in Treatment  1 upvotes 4 months ago
      Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

      community Is it a lot of free testosterone?

      in Finasteride/Dutasteride  3 upvotes 5 months ago
      The conversation discusses hair loss and the impact of testosterone and DHT levels, with suggestions to monitor these levels and consider vitamin D supplementation. Treatments mentioned include finasteride and possibly minoxidil.

      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

      in Treatment  121 upvotes 5 months ago
      Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

      community Topical Dutasteride & Microneedling Works

      in Finasteride/Dutasteride  6 upvotes 5 months ago
      Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.

      community When is GT20029 going to come out?

      in Research/Science  38 upvotes 5 months ago
      The conversation discusses the anticipation and skepticism around the release of GT20029 for hair loss treatment. The original poster has been using Finasteride and Minoxidil but is hopeful for GT20029, while others express doubts about its timely release and suggest alternatives like KX826 and hair transplants.

      community Koshine826 PRO 1% is available

      in Chat  37 upvotes 5 months ago
      The conversation is about the availability of Koshine826 PRO 1% for hair loss treatment. The discussion includes Minoxidil, finasteride, and RU58841.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 6 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community My country is 100 years behind the US in treating hairloss

      in Treatment  188 upvotes 6 months ago
      In the Czech Republic, doctors are largely unaware of hair loss treatments beyond minoxidil, and finasteride is hard to obtain. Many users suggest buying treatments like finasteride and minoxidil from other countries or online.

      community Looking for KX826 (pyrilutamide) success stories

      in Treatment  12 upvotes 6 months ago
      A user ordered pyrilutamide (KX826) to stop hair loss and is seeking success stories. Replies indicate that it's too early to evaluate the product's effectiveness, as it takes several months to see results.

      community So... any chinese suppliers for real pyri?

      in Research/Science  6 upvotes 7 months ago
      The conversation discusses sourcing pyrilutamide from China for hair loss treatment, highlighting its potency compared to other AR antagonists like bicalutamide and RU58841. The user expresses interest in trying pyrilutamide despite mixed results in clinical trials.