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GlossaryKeratinocyte Proliferation (KP)

process where skin cells multiply to regenerate and heal

Keratinocyte proliferation refers to the process by which keratinocytes, the primary cells in the outer layer of the skin, multiply and produce new cells. This process is crucial for skin regeneration and healing, as it helps replace dead or damaged skin cells and maintain the skin's protective barrier. For professionals, understanding keratinocyte proliferation is essential for studying skin conditions and developing treatments for disorders like psoriasis and alopecia.

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community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 71 upvotes 4 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community Solvent for topical fin with low absorption

in Product 2 upvotes 4 months ago

The conversation is about using distilled water as a solvent for topical finasteride to reduce systemic absorption. The user is considering avoiding ethanol and propylene glycol to achieve this.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community Almost 2 month of 1mg fin and Costco min (liquid)

in Is this regrowth? 83 upvotes 4 months ago

A 40-year-old male using 1mg finasteride and Costco liquid minoxidil for almost 2 months reports noticeable improvement in hair regrowth, though his temples remain recessed. Encouragement from others suggests continued use will yield further progress.

community 23M (yes 23, I'm not kidding), ~6 month progress. I'm on the Big 4 + Vitamin Supplement.

in Progress Pictures 447 upvotes 9 months ago

A 23-year-old male shared his 6-month hair loss progress using Minoxidil, Finasteride, Ketoconazole shampoo, microneedling, and vitamin supplements. He noticed hair loss at 19, which accelerated during the pandemic.

community 5% minoxidil &1mg finasteride -7th months- Asian-23M

in Progress Pictures 620 upvotes 1 year ago

A user's successful hair regrowth after 7 months of using 5% minoxidil, 1mg finasteride, and adding micro needling 4 months ago. The user also took biotin, fish oil, and collagen supplements, and reduced finasteride intake to once every 3 days due to minor libido decay.

community HMI-115 when will it be available

in Research/Science 16 upvotes 1 year ago

The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

community HMI 115 Phase 1 update: Changes to clinicaltrials.gov page

in Research/Science 25 upvotes 1 year ago

A Phase 1 update for the HMI 115 clinical trial, which involves 16 participants and is expected to end in July 2023; as well as changes to the recruitment process, including treatment protocols with Minoxidil, Finasteride, and RU58841.

community Can HMI-115 reverse miniaturization?

in Research/Science 12 upvotes 1 year ago

HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

community (Updated) 9month hair gains on fin,min,niz

in Progress Pictures 713 upvotes 2 years ago

A user's nine-month journey of hair growth with treatments including finasteride, minoxidil, and nizoral; some participants thought the user had a hair transplant while others disagreed.

community Has anyone tried hair fibers to cover the bald spot?

in Product 17 upvotes 3 years ago

User discovered hair fibers (Toppik) for covering bald spots and recommends it. Others agree it's a game changer and boosts confidence.

community Hair Loss Drugs Ranked in Order of Efficacy

in Research/Science 67 upvotes 11 months ago

Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

community 22M Fin and min everyday for 10 months, looks like my right temple is still receding

in Finasteride/Dutasteride 67 upvotes 1 year ago

The user is seeking opinions on their hair loss, specifically the receding of their right temple. They are considering switching to Dutasteride but are unsure if it will help. Other users suggest that their hairline has improved with the use of Finasteride and Minoxidil. One user mentions using RU58841 to thicken their hairline.

community Diagnosed with MPB at 16 (Male)

in Treatment 54 upvotes 6 months ago

A 16-year-old diagnosed with male pattern baldness (MPB) was prescribed hair vitamins, vitamin D, a non-ketoconazole shampoo, and redenysl + serum, with a suggestion for GFC or IHRF treatments. Some users recommended minoxidil, ketoconazole, and derma stamping, while others advised against certain treatments until the age of 18.

community 9 months on fin and oral minoxidil (26M)

in Progress Pictures 2325 upvotes 7 months ago

A user shared their positive experience with hair regrowth after 9 months of using 1mg finasteride daily and 2.5mg oral minoxidil every other day, with no side effects. Other users expressed various reactions, from skepticism to hope, and discussed their own experiences with similar treatments.

community Diffuse thinning is the worst man

in Chat 248 upvotes 10 months ago

The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.

community Why do people downplay vitamin deficiency when 94% of Americans are vitamin D deficient?

in Research/Science 132 upvotes 11 months ago

The conversation is about the role of vitamin deficiencies in hair loss and the effectiveness of treatments like Minoxidil, finasteride, and RU58841. It concludes that while vitamins and nutrition are important, they are not the primary solution for androgenic alopecia.

community Minoxidil&Finasteride 7 months progress

in Progress Pictures 936 upvotes 1 year ago

A user shared their 7-month progress using Minoxidil and Finasteride for hair loss, which significantly reversed their aging appearance. They applied Minoxidil twice daily, took 1mg Finasteride once daily, micro-needled weekly, maintained a high protein diet with vitamins and biotin, and recommended a balanced lifestyle for best results.

community 3 Month Diffuse Thinner Update. 23yo Korean.

in Progress Pictures 736 upvotes 1 year ago

The user Consistent-Gene1334 shared their positive results in regrowing hair by using topical minoxidil and oral finasteride. Other users in the conversation praised the results and discussed the effectiveness of these treatments for diffuse thinning.

community 5 months on Finasteride 0.25mg daily – my thoughts and experiences.

in Update 59 upvotes 2 years ago

A 37-year-old person taking 0.25mg of Finasteride daily to treat hair loss, with the goal of saving existing hair rather than regrowing it, who experienced an expected dramatic shed and subsequent improvement in their hair noticeably after 3 months. A 38 year old had a similar experience with the same timeline and result.