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      community Keratin microspheres - breakthrough

       14 upvotes 2 years ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

       4 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community 5-year Minoxidil user quitting after minor heart attack

       5 upvotes 5 years ago
      A user experienced a minor heart attack after combining minoxidil with dermarolling and is considering stopping minoxidil use. They are concerned about hair loss after quitting and are exploring if finasteride or essential oils can maintain hair growth.

      community I'm becoming non-responder to minoxidil. What's going on?

       7 upvotes 1 year ago
      The user experienced reduced effectiveness of minoxidil after consistent use, despite using dutasteride to maintain hair. They are considering alternatives like microneedling and exploring options like hair transplants due to dissatisfaction with current hair density.

      community New study on applying minox right after derma stamp

       47 upvotes 1 month ago
      Microneedling combined with minoxidil and finasteride improves hair growth in androgenetic alopecia, with effectiveness varying by severity. The study was retracted due to concerns about validity and potential AI-generated content.

      community Haircafe slams pp405 presentation. Are results really that bad?

       64 upvotes 5 months ago
      PP405 shows promise in activating dormant hair follicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.

      community Oral PTD-DBM available online, worth giving a shot?

       4 upvotes 6 years ago
      Oral PTD-DBM was discussed as a potential hair loss treatment, but it was deemed ineffective in humans despite promising results in mice. The conversation concluded that trying it without VPA might be unwise.

      community A scary individual report of RU58841.

       33 upvotes 1 year ago
      RU58841 caused severe side effects like heart palpitations and shortness of breath, leading the user to stop using it. Minoxidil and finasteride were effective without side effects, while RU58841's safety and effectiveness remain uncertain.

      community Minoxidil experiment on single hair follicle

       1689 upvotes 1 year ago
      Minoxidil was applied to a single miniaturized hair follicle over four months, resulting in less miniaturization but not yet terminal growth. The user used a 5% minoxidil solution, specifically the Regaine brand, and observed changes using a handheld WiFi microscope.

      community ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data

       17 upvotes 8 months ago
      ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.

      community RU58841 KB Solution vs PG + Ethanol

       6 upvotes 2 years ago
      The conversation discusses the differences between KB solution and PG + Ethanol solution for RU58841 in treating hair loss. It compares the effectiveness and properties of these two solutions.

      community Hair Multiplication Photos from Koehler Lab at Harvard

       15 upvotes 9 months ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841, and highlights hair multiplication research from Koehler Lab at Harvard. Users express optimism about future advancements.

      community KX-826 Phase 3 Failed. Sorry guys...

       51 upvotes 2 years ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Losing the genetic lottery - venting

      in Chat  67 upvotes 4 months ago
      The user is experiencing hair loss and has tried various treatments including topical and oral finasteride, minoxidil, dutasteride, and ketoconazole, but continues to lose hair. They are considering alternative solutions like hair systems due to the lack of improvement and a scalp condition called CVG.

      community RU and cetosomal minoxidil topical

       1 upvotes 7 months ago
      Mixing RU58841 with cetosomal minoxidil is discussed due to scalp irritation from ethanol PG vehicles. A mixture of the two turned bright pink when left to dry.

      community I just got back from the animal hospital and lost my cat

      in Minoxidil  475 upvotes 2 years ago
      A user shared a tragic experience where their cat died after being exposed to Minoxidil, warning others of its toxicity to pets. Some users discussed switching to oral hair loss treatments, while others expressed condolences and shared their own concerns and experiences with topical treatments around pets.

      community Anyone found a scalp applicator WITH a press-down plunger?

       22 upvotes 3 weeks ago
      A user is searching for a specific scalp applicator with a plunger-style button to effectively dispense Minoxidil. They found it out of stock but received help from another user who provided a link to the desired product.

      community Question for all the good Minoxidil responders

       7 upvotes 2 years ago
      The user discusses their experience with minoxidil for hair loss, noting that drinking coffee may reduce its effectiveness. They observed better results with the liquid solution and no coffee compared to using the foam solution and drinking coffee.

      community This shedding fase is absolutely brutal

      in Progress Pictures  181 upvotes 1 year ago
      The user is experiencing severe hair shedding despite using minoxidil, finasteride, ketoconazole shampoo, and dermarolling. They are considering changing treatments after stopping dermarolling and switching finasteride brands worsened the shedding.