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      community I have a question for everyone about the new UCLA research

       10 upvotes 1 year ago
      The conversation discusses skepticism about a new hair loss treatment called project K, which claims to replicate a chemical from UCLA research but is suspected to be a scam. The original poster plans to continue using oral minoxidil, finasteride, and dutasteride, along with microneedling, for hair regrowth.

      community Latest study on RU58841 done 19. August 2026.

       25 upvotes 3 weeks ago
      RU58841 can be absorbed systemically after topical application, but the study did not find immediate hormonal disruption. The study highlights the need for more research on long-term safety and effects of RU58841, as well as the importance of quality control in products from the grey market.

      community Experiment with Growth Factors and Microneedling

       4 upvotes 11 months ago
      The conversation is about experimenting with microneedling and growth factor topicals for hair growth, avoiding Minoxidil due to shedding concerns. The treatment includes microneedling, growth factor topicals, finasteride, biotin, and a caffeine shampoo.

      community My Idea for a possible new hairloss treatment

       53 upvotes 6 years ago
      Exploring a potential hair loss treatment using the enzyme AKR1C2 to locally reduce DHT levels. Challenges include enzyme delivery through the skin and high production costs, with gene therapy or stem cells suggested as future alternatives.

      community KX-826 alone to stop hairloss???

       13 upvotes 10 months ago
      A 28-year-old male experiencing early male pattern baldness is considering using Pyrilutamide (KX-826) as an alternative to finasteride due to side effects. He seeks to maintain his current hair without regrowth and is concerned about potential side effects like reduced libido.

      community been using fake minoxidil for almost 2 years

       20 upvotes 1 year ago
      The user discovered they had been using fake minoxidil for almost two years, which stopped working, and switched to finasteride, which slowed hair loss. They recently started using real minoxidil and noticed a shedding phase, indicating it might be effective.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  20 upvotes 2 years ago
      A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

      community What’s the consensus on RU58841 vs Pyrilutamide (Kx-826)?

       5 upvotes 5 months ago
      RU58841 and Pyrilutamide (Kx-826) are both topical anti-androgens, but neither is effective for hair regrowth. RU58841 has more anecdotal support, while Pyrilutamide has progressed further in trials, though both have limitations.

      community My new experiment: Topical dut with oral fin

       5 upvotes 4 days ago
      A 45-year-old man is using oral finasteride, oral minoxidil, tretinoin, and microneedling for hair regrowth, with plans to add topical dutasteride to improve his hairline. He is considering a hair transplant but is cautious about changing his current regimen.

      community Thinking about using PP405 and RU58841

       1 upvotes 8 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community Is RU58841 really a game changer ?

       30 upvotes 4 years ago
      Topical finasteride and minoxidil show some hair regrowth, but hair loss persists. RU58841 is considered effective by some users but is not well-tested, with potential side effects; it may be used alongside finasteride for better results.

      community Evidence of DUT shedding in clinical trials?

      in Finasteride/Dutasteride  6 upvotes 1 month ago
      Switching from finasteride to dutasteride may cause increased hair shedding, which is not well-documented in clinical trials. Some users report success with dutasteride, but experiences vary, and expectations may influence perceptions of effectiveness.

      community Topical fin, Topical min, RU58841, 0.5 Dermarolling 2x a week

       2 upvotes 11 months ago
      A user is considering using topical finasteride, topical minoxidil, RU58841, and dermarolling twice a week to address hair loss after experiencing side effects with oral finasteride. They previously saw positive results with a topical spray containing finasteride, minoxidil, and tretinoin but discontinued use due to laziness.

      community Consenus on Kx-826/pyrilutamide vs ru58841

       11 upvotes 1 week ago
      KX-826 is considered effective for hair maintenance, with better safety research than RU58841, but lacks positive anecdotes. RU58841 is seen as potentially stronger, but concerns exist about systemic effects; combining anti-androgens with 5AR inhibitors is suggested for better results.

      community DHT levels after 10 months on dut 0.5 ed, how is this even possible?

       2 upvotes 10 months ago
      A user experienced accelerated hairline recession after adding dutasteride to their regimen of topical finasteride and minoxidil, despite reduced hair shedding. They were informed that ELISA testing for DHT levels can be highly inaccurate.

      community peptides seems to have dramatically decreased hairloss!

       85 upvotes 4 months ago
      Peptides like GHK-Cu, BPC-157, and TB-500 have significantly reduced hair loss, with GHK-Cu being particularly effective. The discussion also covers the high cost of these peptides and explores more affordable purchasing options.

      community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

       62 upvotes 1 year ago
      KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

      community Aminexil, Nanoxidil, Stemoxydine and Kopexil. Anyone use them?

       1 upvotes 9 years ago
      Aminexil, nanoxidil, stemoxydine, and kopexil are discussed as alternatives to minoxidil for hair growth, with concerns about dependence. Minoxidil is noted for its effectiveness in transitioning hair growth phases, but dependence is mainly linked to androgenic alopecia.

      community Fin non responders, did Dut ever work? Please share!

      in Finasteride/Dutasteride  17 upvotes 1 year ago
      The conversation discusses the effectiveness of finasteride and dutasteride for hair loss, with some users finding no improvement and experiencing side effects. It also mentions the use of RU58841 and topical minoxidil, highlighting that hair sensitivity to DHT varies among individuals.

      community SOS – The cure for women = PREGNANCY

       2 upvotes 7 months ago
      Pregnancy can temporarily reverse hair loss in women, but attempts to mimic pregnancy hormones with treatments like contraceptive pills, spironolactone, estradiol, progesterone, finasteride, and minoxidil have been ineffective. The discussion highlights the need for research into the hormonal mechanisms of pregnancy that affect hair regrowth.

      community Old study where balding man in his 70s burned his scalp and regrew all his hair

       177 upvotes 5 months ago
      The conversation discusses unconventional methods for hair regrowth, including scalp trauma like burning or microneedling, and compares them to treatments like Minoxidil and Finasteride. It highlights skepticism about these methods and the body's unpredictable healing responses.

      community who in here has used ru58841 , and how did it go

       11 upvotes 8 months ago
      RU58841 had mixed results for hair regrowth, with some users experiencing no change and others noting regrowth but also side effects like libido issues and chest pain. Some users combined it with other treatments like finasteride and dutasteride, with varying effectiveness.

      community is anyone using ru58841 against acne?

      in Technology  3 upvotes 1 year ago
      RU58841 is discussed as a potential treatment for acne and hair loss, with users debating its effectiveness and safety compared to other treatments like finasteride, minoxidil, and dutasteride. Concerns about RU58841's side effects and lack of clinical trials are raised, while some users share their personal experiences and routines involving RU58841 for hair loss.