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      community The mechanism of androgenic alopecia

       36 upvotes 11 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community What is fluridil binding affinity?

       5 upvotes 4 years ago
      Fluridil is hard to obtain and only available in Slovakia and Czechia, with no systemic side effects but possibly limited effectiveness compared to finasteride. The original poster is using finasteride and minoxidil without success and is considering trying fluridil despite its cost.

      community The dose dependent nature of the cardiac effects RU58841

       5 upvotes 8 months ago
      Reducing the dose of RU58841 from 25mg to 7.5mg topically helped minimize heart palpitations. Users discussed the cardiac effects of RU58841 and minoxidil, noting that no treatment is completely free of side effects.

      community Combining Stemoxydine + Topical Minoxidil

      in Minoxidil  2 upvotes 1 year ago
      Combining stemoxydine with topical minoxidil for hair loss treatment. Users discuss application order and effectiveness, with some skepticism about stemoxydine's benefits.

      community Non responsive diffuse thinning

      in Progress Pictures  9 upvotes 11 months ago
      The user has been experiencing diffuse hair thinning despite using finasteride, minoxidil, dermarolling, clobetasol cream, and PRP sessions. They seek advice on additional treatments and are advised to check vitamin D, iron, and thyroid levels.

      community Minoxidil may have poisoned my cat

      in Minoxidil  45 upvotes 4 months ago
      A user expressed concern that minoxidil might have poisoned their cat, leading to heart and lung issues, but others suggested it was unlikely due to minimal exposure. Some users recommended switching to oral minoxidil or using protective measures like a bonnet to prevent potential contact with pets.

      community Is there new research about pumpkin oil as a DHT blocker (2026)?

       11 upvotes 4 months ago
      Pumpkin seed oil is considered a weak DHT blocker compared to finasteride and dutasteride, with some users reporting side effects like mood changes and reduced libido. Despite some anecdotal benefits for urinary issues, it is not effective for hair loss, and finasteride is preferred by some users for its lack of side effects.

      community What Hinders the Absorption of Minoxidil?

      in Minoxidil  1 upvotes 1 year ago
      Silicone and dimethicone in shampoos may hinder Minoxidil absorption, while Tretinoin and microneedling can enhance its efficacy. Users discuss applying Tretinoin before Minoxidil, waiting for it to dry first.

      community Attempting to assist people with gyno sides on finasteride

       23 upvotes 2 years ago
      Finasteride can cause gynecomastia due to hormonal imbalances. Management includes consulting an endocrinologist and using aromatase inhibitors like anastrozole or supplements like DIM and zinc.

      community Topical Finasteride in DMSO works?

      1 month ago
      Topical finasteride in DMSO is discussed as a potential treatment for hair loss. Users share experiences and opinions on its effectiveness.

      community Finasteride with an aromatase inhibitor

       5 upvotes 6 years ago
      The conversation is about managing potential gynecomastia from finasteride use. The user considers using an aromatase inhibitor and plans to check hormone levels.

      community Should I consider a crown transplant?

       29 upvotes 1 month ago
      The user is considering a crown transplant but is advised to try topical finasteride or dutasteride alongside minoxidil first, as transplants without these treatments may not be effective. They experienced lower libido with oral finasteride and are exploring other options like topical treatments and red light therapy.

      community 2+ Years of Finasteride treatment - Stopped hair-loss, got regrowth, but

       24 upvotes 1 year ago
      The user experienced successful hair regrowth with Finasteride and Minoxidil but developed erectile dysfunction and abdominal pain, possibly due to medication or lifestyle changes. They plan to consult a urologist and consider adjusting medication or trying supplements like zinc, DIM, or boron.

      community To stop or not to stop minoxidil?

       2 upvotes 3 years ago
      A female user experienced hair loss after Covid and used Minoxidil 5% but saw more hair loss over time. She also uses alfatradiol, topical MSM, and betamethasone sporadically, and is unsure if Minoxidil is beneficial.

      community Oral Minoxidil- Be Careful!!!!!

      in Minoxidil  417 upvotes 1 year ago
      Oral minoxidil can cause severe side effects, including heart issues, even at low doses. Users suggest starting with a lower dose or using topical treatments to minimize risks.

      community Can trichodynia ruin an exosome treatment?

      in Chat  1 upvotes 2 years ago
      The user has tried various hair loss treatments including topical minoxidil, oral finasteride, oral dutasteride, oral minoxidil, and exosome therapy, but none have been effective. They suspect trichodynia might be preventing these treatments from working.

      community Indian Subcontinent specific : Fin effects

       4 upvotes 6 years ago
      Oral finasteride is recommended over topical finasteride for men in the Indian subcontinent, with no reported side effects. Minoxidil and dermarolling are also suggested, while dietary supplements and topical finasteride are deemed less effective.

      community Severe diffuse thinning since 13 years old

      in Treatment  6 upvotes 1 year ago
      A 15-year-old experiencing severe diffuse thinning plans to use minoxidil, dermarolling, and possibly ketoconazole, with hopes to later incorporate finasteride. Concerns about starting finasteride too young and the need for a dermatologist consultation are discussed.