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      community Recommendations for topical antiandrogens

      in Treatment  2 upvotes 9 months ago
      The conversation is about adding a topical anti-androgen to a hair loss treatment regimen that includes dutasteride and oral minoxidil. The user is considering topical finasteride or dutasteride, Nizoral shampoo, KX-826, and topical spironolactone, while avoiding RU58841 due to safety concerns.

      community Going to inject NAD+ and GHL-Cu into Scalp for a few months

      in Chat  1 upvotes 1 year ago
      The conversation discusses a user's plan to inject NAD+ and GHK-Cu into their scalp to improve hair health, with concerns raised about the risks of infection and necrosis. Alternatives like finasteride, dutasteride, microneedling, oral minoxidil, and scalp massages are suggested.

      community finastride and minxidil have changed my life

      in Progress Pictures  98 upvotes 9 months ago
      A user shared their positive experience with hair regrowth using 1mg finasteride and 5% topical minoxidil daily, showing significant improvement in hair density over six months. The conversation includes supportive comments and questions about the treatment details, such as whether finasteride was taken orally or topically and if microneedling was used.

      community The end of minoxidil and fin/dut regime

       106 upvotes 6 months ago
      New hair loss treatments like GT20029 and PP405 could potentially replace minoxidil and finasteride, offering better results with fewer side effects. However, current treatments like finasteride and minoxidil are still effective for many, despite concerns about side effects.

      community Attacking DHT synergistically both locally at the scalp and systemically = Greater Success??

      in Finasteride/Dutasteride  15 upvotes 1 year ago
      The user has been using oral Dutasteride, RU58841, and Minoxidil for three years without success and is considering adding topical Finasteride or Dutasteride to target DHT both locally and systemically. Other users suggest sticking to a consistent treatment plan, exploring different combinations, and considering other factors like potential misdiagnosis or inconsistent medication use.

      community anybody here having success with Topical Spironolactone?

       4 upvotes 3 years ago
      The user plans to mix Kirkland minoxidil with spironolactone tablets for hair loss. They cannot use finasteride, saw palmetto, or spearmint tea due to side effects like insomnia and low testosterone.

      community New molecule PP405 vs exercise

       36 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community Additional supplements for min/fin treatment?

       5 upvotes 10 months ago
      Consider taking vitamin D3 and using tretinoin with minoxidil and finasteride for hair loss. Rosemary essential oil may improve hair appearance.

      community Thinking about using PP405 and RU58841

       1 upvotes 8 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community carriers other than PG for ru58841 ? Help !!

       5 upvotes 1 year ago
      The user is seeking alternatives to propylene glycol and glycerin for mixing with RU58841 due to allergies and greasiness. Suggestions include reducing glycerin and considering stemoxydine as a solvent.

      community Are Ru58841/Kx826 effective as fin?

      in Treatment  1 upvotes 1 year ago
      The user is considering switching from topical finasteride to RU58841 or KX826 due to side effects like low libido and ED. They are also using oral minoxidil and considering low-dose saw palmetto to maintain their hairline.

      community KX-826 1% Phase II Results from China Just Dropped

       37 upvotes 1 year ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community What's the best/"safest" topical anti androgen on the market currently?

       1 upvotes 11 months ago
      The user experienced decreased libido with saw palmetto and is now considering topical anti-androgens like RU58841, pyrilutamide, and topical dutasteride for hair loss. Minoxidil is also mentioned as a potential addition, but the user is cautious about side effects and availability of treatments.

      community Increased efficacy of fin/dut: with or without meal?

       6 upvotes 4 months ago
      Taking dutasteride with a meal containing fat may improve absorption, but consistency in routine is more important than timing. Minor variations in absorption won't significantly affect efficacy due to dutasteride's long half-life.

      community Upcoming and current hair growth stimulants (2026)

      in Research/Science  94 upvotes 7 months ago
      The conversation discusses various hair growth treatments, including topical and oral minoxidil, microneedling, LLLT, PRP, exosomes, latanoprost, copper peptides, and upcoming treatments like PP405 and Vdphl01. It also covers managing side effects of minoxidil, such as dry scalp, and mentions the use of dutasteride and finasteride for hair loss.

      community TH07 by Triple Hair entering phase III trial

      6 months ago
      A new topical treatment, TH07, combining finasteride, latanoprost, and minoxidil, is entering phase III trials with promising early results. Some users express skepticism, noting the treatment uses existing products.

      community Do we have anything in the pipeline that is used as a replacement for minoxidil?

      in Minoxidil  17 upvotes 1 year ago
      The conversation discusses hair loss treatments, focusing on alternatives to Minoxidil, such as Bimatoprost and Latanoprost, and the use of Finasteride, Dutasteride, RU58841, and microneedling. The user plans to add Latanoprost to their regimen, which already includes oral and topical Minoxidil and Finasteride, Ketoconazole shampoo, and microneedling.

      community If dutesteride and oral minoxidil doesn’t work that’s it right?

      in Treatment  20 upvotes 2 years ago
      A user is experiencing continued hair loss despite using 0.5mg dutasteride and 2.5mg minoxidil, and is seeking advice on why the treatments aren't working and how to address potential androgen receptor sensitivity. Replies suggest getting tested and considering scalp micropigmentation (SMP).

      community Topical 5% minoxidil vs compounded topical spray

       3 upvotes 5 months ago
      A user is considering switching from regular 5% minoxidil foam to a compounded 5% minoxidil spray with added caffeine, melatonin, and tretinoin for easier application and potentially better results. Another user mentions that tretinoin can enhance minoxidil's effectiveness by converting it to its active form.

      community Im looking for a topical to add to my current stack

      in Treatment  1 upvotes 1 year ago
      The user is considering adding a topical treatment to their current regimen of finasteride and oral minoxidil to protect their temple area, with options like piro, RU58841, or topical finasteride or dutasteride. They are advised against overcomplicating their treatment, but another user suggests a topical with 8% minoxidil/dutasteride for better results.

      community Topical melatonin shows some promise.

       4 upvotes 10 years ago
      Topical melatonin shows promise for increasing hair density with minimal side effects. The user is transitioning from oral finasteride to a compounded minoxidil and finasteride solution and considering melatonin and bimatoprost as additional treatments.

      community Similar 5ar inhibitors to fin?

      5 years ago
      Natural vitamins like pumpkin seed oil, saw palmetto, and ecklonia cava are discussed for their potential to lower DHT levels. They may work similarly to finasteride but are significantly weaker.