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60-90 / 1000+ resultscommunity 2020 Hair and Scalp Treatments: A Clinical Guide (in Depth 350 Page Guide)
Treatments for hair loss, including topical immunotherapy, regenerative treatments, laser and light-based therapies, oral supplements, intralesional steroids, and new drugs like finasteride and minoxidil.
community Interesting new publication suggesting that MPB should be assessed as a early warning sign for type-2 diabetes.
Male pattern baldness (MPB) may be an early warning sign for type 2 diabetes due to its association with insulin resistance. Treatments discussed include testosterone therapy and finasteride, which affects hormone levels related to hair loss and insulin sensitivity.
community Forgotten 'Total Revival' Stack
Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.
community mallia therapeutics 8T3 scd83 molecule for ffa/lpp mainly and aga
A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.
community Any concrete cases of people who were told they couldn't have a transplant because of microneedling?
Microneedling before a hair transplant may harden the scalp and affect blood circulation, potentially impacting graft growth. Some users report successful transplants after microneedling, while others advise caution and consulting with a surgeon.
community Any interesting future treatments around the corner
Potential future hair loss treatments include stem cell therapy, Clascosterone (Breezula), Amplifica's signaling molecules, Botox, and dutasteride mesotherapy. Some treatments are promising but expensive, like Tsuji's technique, while others, like Botox, show unexpected results.
community Verteporfin for transplant site?
community Transplant and people with diabetes.
The conversation discusses the experiences of individuals with type 1 or type 2 diabetes undergoing hair transplants, focusing on healing, A1C levels, and associated risks. It does not mention specific treatments like Minoxidil, finasteride, or RU58841.
community Do I have Alopecia Areata, TE or MPB?
community Natural/Herbal MPB Treatments
community So what is the most compelling current research on a cure?
Setipiprant, a PGD2 inhibitor, and RepliCel, a cell transplantation technology, are being explored as potential hair loss treatments. Current mainstream treatments like Minoxidil and Finasteride have limitations due to side effects and efficacy.
community Gut microbiome imbalances linked to scalp inflammation and hair follicle impact
Gut microbiome imbalances can cause scalp inflammation and affect hair follicles, potentially leading to hair loss. Treatments include finasteride, peptides like BPC-157, TB-500, KPV, and lifestyle changes such as diet and exercise.
community Low dose corticosteroids for treatment of DUPA?
The user is exploring the use of low-dose corticosteroids, specifically hydrocortisone, to treat hair thinning associated with DUPA, alongside finasteride, oral minoxidil, pyrilutamide, and keto shampoo. They are cautious about long-term steroid use due to potential side effects and are considering dietary changes to address possible autoimmune connections.
community Vitamin E and K deficiency (F,25)
Vitamin E and K deficiencies due to exocrine pancreatic insufficiency may affect hair growth. A scalp biopsy is recommended to check for autoimmune-related hair loss.
community Is "hair stem cell transplant" legitimate?
The conversation discusses the legitimacy of hair stem cell transplants, with skepticism about their effectiveness and claims of infinite grafts. Some users mention alternative treatments like verteporfin and share experiences with different clinics and doctors.
community A Short Recap on PP405 and AAD 2026
PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.
community Community ranking on what new drugs/studies we are most hopeful about?
The conversation discusses potential hair loss treatments, including clascoterone, GT20029, ET-02, VDPHL01, and PP405, with hopes for new options by 2028. Current treatments like minoxidil and finasteride are expected to remain effective, with clascoterone and VDPHL01 as promising alternatives.
community TGF-Beta. Good or Bad? Help for treatment investment
TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.
community do hyper responders just have better absorption in there gut?
The conversation discusses the impact of H. pylori on nutrient absorption, specifically iron and B12. It also mentions checking serum DHT levels as a potential solution.
community CRISPR treatment for AGA on the horizon after approval for blood disorders
CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.
community Dermatology expert panel on permanent chemotherapy induced alopecia (PCIA)
Chemotherapy can cause permanent hair loss similar to androgenetic alopecia. Oral minoxidil and scalp cooling are suggested treatments.
community Post Low-Level Laser Light Therapy Syndrome (PLLLTS )
Hair loss discussion includes LLLT treatments and a satirical condition called PLLLTS, causing patients to resemble lighthouses and attract moths. Some users express concern about others taking the satire seriously.
community Why the cure is not yet found and why it is always 5 years away? Why no hopes on PP405, GT, KX, Hair cloning, AMP, etc, etc, etc
Skepticism about hair loss research motivations, suggesting financial interests hinder finding a cure. Mentions treatments like minoxidil, finasteride, and dutasteride, but notes they are not cures.
community Has anyone here actually undergone experimental (grey market) hair cell therapy/follicle cloning?
Hair cell therapy and follicle cloning are still in experimental stages, with treatments like hair multiplication and regenerative hair therapy being marketed but not yet proven to create unlimited new follicles. There is skepticism about the effectiveness and legitimacy of these treatments, with some considering them scams.
community Pyrilutamide PG/ETH itching scalp
community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia
Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.
community Pp405 AAD presentation tomorrow - fingers crossed - what to expect?
New hair loss treatments PP405 and VDPHL01 are discussed with skepticism and hope, alongside existing treatments like minoxidil and finasteride. Users express frustration over limited progress since the 1980s but remain cautiously optimistic.
community They’re curing cancer before solving baldness
The conversation humorously discusses the prioritization of curing cancer over solving baldness, with mentions of treatments like finasteride and dutasteride. Participants express frustration over the lack of focus on hair loss solutions compared to cancer research.