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      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

       59 upvotes 5 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Progressi in 9 mesi, da luglio 2025 a marzo 2026

      in Progress Pictures  153 upvotes 5 months ago
      The user shared their 9-month hair regrowth progress using topical Minoxidil 5%, finasteride 0.05%, retinoic acid 0.01%, dermastamping, ketoconazole shampoo, and supplements like biotin. They experienced some hair density improvement but minimal change in the hairline, with initial side effects from finasteride that resolved after dosage adjustment.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 9 months ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community 4 month update to my hair regrowth journey

      in Progress Pictures  74 upvotes 1 year ago
      The user shared a four-month update on their hair regrowth journey using 1mg daily finasteride, 5mg daily oral minoxidil, and weekly dermarolling, noting significant improvement in hair thickness and uniform growth. They reported no side effects from minoxidil except increased hair growth on arms, fingers, and eyelashes.

      community 1 year on Fin and Min. Diffuse thinner.

      in Is this regrowth?  18 upvotes 1 year ago
      The conversation is about a user experiencing hair loss who has been using finasteride for a year and minoxidil once a day for five months, but still experiences shedding and thin hair. The user is considering switching to dutasteride next year and shares their progress with others using similar treatments.

      community Shed 2 years into finasteride and minoxidil

      in Minoxidil  8 upvotes 2 years ago
      A user has been on finasteride for 1.5 years and minoxidil for 2 years, experiencing worsening hair shedding, losing 300+ hairs per wash. They are concerned if this indicates the medicine isn't working and are seeking others' experiences.

      community RU58841 User Feedback - How many of you has it helped

       31 upvotes 4 years ago
      RU58841 has helped many users reduce hair shedding and improve hair thickness, with some experiencing side effects like libido changes. Users often combine it with other treatments like minoxidil, finasteride, and ketoconazole shampoo for better results.

      community 50 years old 4.5 months on Fin

       28 upvotes 4 years ago
      A 50-year-old user shared their positive experience with hair regrowth using finasteride, minoxidil, biotin, pumpkin seed oil, derma rolling, biotin shampoo, and Nizoral. They reported significant improvement in hair density and regrowth, especially in the crown and mid-scalp areas, with no side effects.

      community Finasteride for 2 years - am I any worse off?

       15 upvotes 1 week ago
      The user has been using finasteride for 2 years with visible improvement and stabilization in hair loss, taking 1mg daily without side effects. Some users suggest adding minoxidil for more regrowth potential.

      community 1 month after switching to topical Dut

      in Is this regrowth?  216 upvotes 2 months ago
      The user switched from topical finasteride/minoxidil to topical dutasteride/minoxidil, reporting thicker hair after one month. They used Happy Head products with 0.3% dutasteride and 8% minoxidil.

      community Is there new research about pumpkin oil as a DHT blocker (2026)?

       11 upvotes 4 months ago
      Pumpkin seed oil is considered a weak DHT blocker compared to finasteride and dutasteride, with some users reporting side effects like mood changes and reduced libido. Despite some anecdotal benefits for urinary issues, it is not effective for hair loss, and finasteride is preferred by some users for its lack of side effects.

      community 1 Year and Month (nearly) 1mg of only Fin daily

      in Progress Pictures  96 upvotes 5 months ago
      The conversation discusses hair loss treatment using finasteride, with the user noting improvements in hair density but a recent decrease in vertex density. Suggestions include adding minoxidil, but the user avoids it due to its toxicity to cats and considers oral minoxidil instead.

      community Update: going nuclear! (Switch to dut)

      in Update  13 upvotes 5 months ago
      The user had a hair transplant in March 2025 and has been using finasteride since 2023, which halted hair loss but didn't fully restore density. They plan to use dutasteride twice weekly, finasteride five times a week, and saw palmetto to improve hair thickness.

      community Old study where balding man in his 70s burned his scalp and regrew all his hair

       177 upvotes 5 months ago
      The conversation discusses unconventional methods for hair regrowth, including scalp trauma like burning or microneedling, and compares them to treatments like Minoxidil and Finasteride. It highlights skepticism about these methods and the body's unpredictable healing responses.

      community One Year Progress, keep the faith

      in Progress Pictures  286 upvotes 5 months ago
      The conversation is about a user's one-year progress in treating hair loss using a combination of finasteride and minoxidil spray, derma rolling, and Nizoral shampoo. The user reports significant improvement and increased confidence, while others offer advice and express admiration for the results.

      community 9-Month Routine Update. Advice?

       3 upvotes 5 months ago
      The user has been using 1mg Finasteride and 5% topical Minoxidil for 9 months with little improvement and has recently added microneedling, showing slight progress. The new protocol includes switching to 5mg oral Minoxidil, continuing microneedling, and adding Anagenil Complex, while seeking advice on whether to stop topical Minoxidil and the effectiveness of Anagenil Complex.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 8 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community Stem cells for hair, does it work?

      in Technology  8 upvotes 9 months ago
      Stem cell treatments for hair restoration can be effective, but results vary and depend on factors like the type of stem cells used and timing of treatment. PRP and exosomes have shown some success, while costs and effectiveness differ by location, with South Korea and Turkey offering more affordable options.

      community 9 months on Finasteride and still no progress and feeling hopeless

       38 upvotes 11 months ago
      The user has been using finasteride, minoxidil, microneedling, PRP, and ProCell therapy for hair loss but sees no progress after nine months. They are considering switching to dutasteride and possibly a hair transplant, with suggestions to add oral minoxidil.

      community Minoxidil & Finasteride Journey

      in Progress Pictures  187 upvotes 1 year ago
      The user started using minoxidil in September 2024 and finasteride in February 2025, along with dermal rolling, rosemary and clove water, and copper peptide serum for hair growth. They experienced positive hair growth results but had issues with a poorly done scalp micropigmentation (SMP) tattoo, which they are in the process of removing with laser treatments.

      community Just Minoxidil 5% twice a day for 5 months

      in Progress Pictures  584 upvotes 1 year ago
      Significant hair regrowth was achieved using 5% Minoxidil twice daily and weekly microneedling with a 0.8 mm dermaroller over five months. Finasteride was not used due to concerns about side effects and availability in France.