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      community Expectations control for SCUBE3

       20 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community 9-Month Routine Update. Advice?

       3 upvotes 5 months ago
      The user has been using 1mg Finasteride and 5% topical Minoxidil for 9 months with little improvement and has recently added microneedling, showing slight progress. The new protocol includes switching to 5mg oral Minoxidil, continuing microneedling, and adding Anagenil Complex, while seeking advice on whether to stop topical Minoxidil and the effectiveness of Anagenil Complex.

      community 10 month meds progress before/after

       81 upvotes 4 months ago
      A user shared their 10-month progress using finasteride, minoxidil foam, occasional microneedling, Regenera Activa, and exosomes for hair loss, reporting no side effects. They occasionally use Nizoral shampoo for a dry scalp.

      community Having Ru58841 mailed to my house

      in Research/Science  1 upvotes 7 months ago
      RU58841 can be ordered as a powder and compounded at home, but it should be stored at room temperature to avoid crystallization. Pyraulatmide may follow a similar principle.

      community Targeted Follicular Finasteride Delivery: A Low-Systemic Strategy

       15 upvotes 5 months ago
      A peptide-based delivery system for finasteride shows promise in reducing systemic side effects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.

      community ASCEplus HRLV Exosomes with microneedling

       1 upvotes 2 years ago
      The discussion is about using ASCEplus HRLB exosomes for hair loss treatment, which combines 10 billion exosomes with growth factors, nutrients, biotin, and copper tripeptide. The treatment is expensive and typically administered via scalp injections, but in Europe, it's done with microneedling.

      community An arthritis drug that can be used for Alopecia.

       5 upvotes 4 years ago
      An arthritis drug, baricitinib, is discussed as a potential treatment for autoimmune alopecia, not androgenetic alopecia. Ritlecitinib is also mentioned as a possible treatment for scarring alopecia.

      community Progressi in 9 mesi, da luglio 2025 a marzo 2026

      in Progress Pictures  153 upvotes 5 months ago
      The user shared their 9-month hair regrowth progress using topical Minoxidil 5%, finasteride 0.05%, retinoic acid 0.01%, dermastamping, ketoconazole shampoo, and supplements like biotin. They experienced some hair density improvement but minimal change in the hairline, with initial side effects from finasteride that resolved after dosage adjustment.

      community MinoxidilMax Latanoprost .01%. Has anybody found this helpful?

       1 upvotes 2 years ago
      The conversation is about the effectiveness of a hair loss treatment product containing 0.01% Latanoprost, with the user considering trying it as a vehicle for RU58841. The user questions whether the dosage is too low to be effective.

      community 9-Month Routine Update. Advice?

      in Update  1 upvotes 5 months ago
      The user has been using 1mg Finasteride and 5% topical Minoxidil for 9 months with little improvement and is now switching to 5mg oral Minoxidil, continuing microneedling, and adding Anagenil Complex. They are seeking advice on whether to stop topical Minoxidil and the effectiveness of Anagenil Complex.

      community RU58841 works great!

       7 upvotes 5 years ago
      RU58841 stopped hair shedding and increased hair density for the user, who experienced side effects from finasteride. The user's regimen includes RU58841, minoxidil, microneedling, Nizoral, and plans to add castor oil.

      community Making your own RT1640 in China

      4 years ago
      RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

      community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

       110 upvotes 2 years ago
      Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

      community 9 months of treatment, fin-min derma NW 6 💥

       74 upvotes 9 months ago
      The user shared progress after 9 months of using finasteride, minoxidil, and dermarolling for hair loss, despite some inconsistency in treatment. They are pleased with the results and plan to stop updating.

      community 9 Months Progress on Fin and min

       284 upvotes 6 months ago
      The user experienced significant hair growth and density improvement over nine months using 1 mg finasteride daily, initially 5% topical minoxidil, then transitioning to 2.5 mg and later 5 mg oral minoxidil, along with weekly microneedling. Noticeable changes were observed after three months, with the most significant progress by month nine.

      community Amplifica and AMP-303 clinical phase 1

       9 upvotes 2 years ago
      Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

       13 upvotes 9 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Kintor KX-826 Discounts (and is the 0.9% more effective)?

       5 upvotes 9 months ago
      Kintor KX-826, a hair loss treatment, is being discussed for its pricing and effectiveness, with a focus on whether the 0.9% concentration is more effective than the 0.5%. Users are seeking cheaper purchasing options.

      community Low Dose Naltrexone For Inflammatory Hair Loss

       10 upvotes 1 year ago
      Low Dose Naltrexone (LDN) may reduce inflammation in alopecia conditions. It is discussed as a potential adjunct treatment with finasteride or dutasteride for androgenic alopecia.

      community 9 months 1.2mg fin 3mg min oral

       10 upvotes 2 days ago
      The conversation discusses hair loss treatments, specifically using 1.2mg finasteride and 3mg oral minoxidil over 9 months. The user reports progress but notes a recent decrease in hair density, possibly due to shedding.

      community 9 month fin progress (1mg/day) - May 2025 to Jan 2026

      in Finasteride/Dutasteride  16 upvotes 5 months ago
      A user shared their 9-month progress using 1mg daily finasteride, noting initial side effects like low libido and ED that resolved over time, and advised staying on the treatment for at least a year before considering a hair transplant. Other users suggested adding minoxidil for better results and recommended using ketoconazole shampoo for dandruff.

      community My two months experience with RU58841

       43 upvotes 4 years ago
      The conversation discusses using RU58841 for hair loss, with OP applying a 5% premixed solution from Receptorchem daily. Users express skepticism about the rapid results and inquire about other treatments and costs.