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      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

       213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community 3 months progress DIY topical fin/min

       16 upvotes 1 month ago
      The user reported slight hair improvement after three months using a DIY topical mix of crushed finasteride tablets and minoxidil solution. They are hoping for more coverage, especially on the crown, despite starting treatment late.

      community Similar 5ar inhibitors to fin?

      5 years ago
      Natural vitamins like pumpkin seed oil, saw palmetto, and ecklonia cava are discussed for their potential to lower DHT levels. They may work similarly to finasteride but are significantly weaker.

      community The homeless crackhead protocol

       4487 upvotes 1 year ago
      The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.

      community Haircafe slams pp405 presentation. Are results really that bad?

       64 upvotes 5 months ago
      PP405 shows promise in activating dormant hair follicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.

      community PP405 ON TEMU....seriously come on

      in Satire  145 upvotes 5 months ago
      A fake hair loss product called "PP405" is being humorously discussed, with users joking about its effectiveness and availability on resale websites. The consensus is that it's a scam, with some users sarcastically claiming miraculous results.

      community 4 month progress. Oral fin and topical min

       1445 upvotes 1 year ago
      A user shared their 4-month hair regrowth progress using oral finasteride and topical minoxidil, reporting no side effects and positive feedback on their appearance. The post sparked debate, with many users doubting the authenticity of the photos, while others congratulated the user on their impressive results.

      community Can't help but feel somethings wrong (MtF 18)

       4 upvotes 5 months ago
      The user is experiencing hair loss and is using treatments like finasteride, minoxidil, and hormone replacement therapy (estradiol enanthate injections) to address it. They are advised to be patient with the treatments and consider using a dermapen for microneedling.

      community 35M | 5-8 Months Hair Transplant Update | 6400 Grafts DHI | Formerly NW7 + SMP

       13 upvotes 2 weeks ago
      A 35-year-old man underwent a 6400 graft DHI hair transplant in Turkey, combined with scalp micropigmentation (SMP), to address severe hair loss from Norwood 7. He uses finasteride, oral and topical minoxidil, and GHK-CU, and is satisfied with the results, noting improved hair coverage and confidence despite some remaining thin areas.

      community What do you think of these hair transplants?

       308 upvotes 9 months ago
      Hair transplants in Bangkok are praised for their natural appearance, with a zigzag hairline design being favored over straight lines. The clinic Hairtran and Dr. Patty receive positive feedback, though some users express skepticism about photo filters and the authenticity of results.

      community progress ? Min / Fin (11 months) + hrt (8 months)

       5 upvotes 3 weeks ago
      The user has been using Minoxidil, Finasteride, and HRT for hair regrowth, but is not fully satisfied with the progress after 11 months. They are considering changing treatments, including possibly switching to Dutasteride and adjusting their HRT regimen.

      community 8 months post op Dr Christina HDC Cyprus

      in Transplants  261 upvotes 1 year ago
      A 40-year-old shared their positive experience with a second hair transplant at HDC Cyprus, involving 4148 grafts and costing around 9,000 euros. They used oral minoxidil, Dutasteride, biotin, and vitamins to aid recovery and were pleased with the results.

      community Hair cloning breakthrough, this might just be the big one ?

       418 upvotes 6 months ago
      Japanese scientists discovered ABM cells, enabling successful human hair follicle cloning, potentially curing hair loss. The treatment may be available in Japan by 2028, but it will be expensive and require travel.

      community 12M post-op +dutasteride daily / FUE 3000Hairs in Korea

       522 upvotes 2 years ago
      A user shared progress pictures 12 months after a hair transplant and daily use of dutasteride. The conversation discusses the quality of comparison photos and the use of hair fibers.

      community Early impressions Rootique Dou + Ulo low dose finasteride

       5 upvotes 4 months ago
      A user shares their positive experience using the Rootique Dou applicator with 0.005% finasteride, noting it effectively delivers the product without greasiness and helps with hair regrowth without side effects. Another user reports regrowth using low-dose finasteride from ULO, while avoiding tretinoin due to skin irritation.

      community Rejux-3x - the copper peptide combo that tressless overlooks.

       1 upvotes 5 months ago
      Rejuv-3X, a topical blend with GHK-Cu, AHK-Cu, and JXL-089, is used for hair loss, offering a targeted option without finasteride's side effects. The user plans to combine it with microneedling for enhanced results.

      community Rant: How to stop hating myself for delaying treatment?

       11 upvotes 1 year ago
      The conversation discusses regret over delaying hair loss treatment, specifically with finasteride, and the emotional impact of hair loss. The user eventually stabilized their hair using oral finasteride after trying other treatments like topical finasteride, Fluridil, and Alfatradiol, and is considering future options like a hair transplant.

      community Miniaturization(?) after 12 months on oral fin/min compound

       13 upvotes 1 month ago
      After 12 months on an oral compound of finasteride, minoxidil, and biotin, the user experienced a seasonal shed and noticed thinner hairs at the hairline, raising concerns about ongoing miniaturization. Another user shared a similar experience and mentioned switching to dutasteride after genetic testing showed finasteride was ineffective.

      community 4 months progress using 2.5mg min, 1mg fin and 10mg biotin.

       42 upvotes 7 months ago
      A user shared their 4-month progress using 2.5mg minoxidil, 1mg finasteride, and 10mg biotin, noting slight testicular discomfort initially but no significant hairline changes yet. Another user reported similar treatment results, with hair darkening at the scalp center and small temple hairs.

      community Any other non-responders to most medications?

       6 upvotes 3 years ago
      The user has not seen results from various hair loss treatments including finasteride, dutasteride, minoxidil, and others over several years and is considering adding RU58841 and starting hormone replacement therapy. They are also experiencing anxiety and contemplating moving to a more accepting environment for their nonbinary identity.

      community HRT temple regrowth - 0 months, 3 months, 6 months

       22 upvotes 2 months ago
      The conversation is about hair regrowth progress using hormone replacement therapy (HRT) with Estradiol and Cyproterone, without using Minoxidil. The user shares progress pictures over 0, 3, and 6 months.

      community KX-826 users: 0.5% vs 0.9% vs foam

      in Technology  6 upvotes 1 year ago
      KX-826 is being discussed for hair loss treatment, with users debating between 0.5% and 0.9% solutions and foam. Some report side effects like headaches, while others see no changes; it blocks androgen receptors without reducing DHT levels.

      community PP405 mechanism question - looking for discussion

       7 upvotes 5 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

       4 upvotes 2 years ago
      The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.