Hair loss discussion includes treatments Minoxidil, Finasteride, and RU58841. Prolactin's role in immune system's antitumor activity raises safety concerns for HMI-115.
Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.
The conversation discusses the potential use of thermal paper receipts, which contain estrogen, as a treatment for hair loss. Participants humorously debate its effectiveness compared to established treatments like Minoxidil and finasteride.
A 30-year-old man experienced significant hair loss after starting testosterone replacement therapy (TRT), which did not improve with daily finasteride and minoxidil. He is considering restarting TRT and is seeking advice on using pyrilutamide or RU58841 to prevent further hair loss.
Sulforaphane shows potential for hair regrowth, with users reporting reduced shedding and regrowth. Some users combine it with Minoxidil and finasteride for better results.
The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.
Start hair loss treatments early for best results. Finasteride, Dutasteride, Minoxidil, and microneedling are commonly used, with some users experiencing side effects but often regretting delayed treatment.
RU and Pyri block androgen receptors to prevent hair loss but may also hinder hair regrowth since they prevent testosterone, which can stimulate hair growth, from binding to these receptors. The user is questioning if this understanding is correct.
A 23-year-old male shared his 6-month hair loss progress using Minoxidil, Finasteride, Ketoconazole shampoo, microneedling, and vitamin supplements. He noticed hair loss at 19, which accelerated during the pandemic.
HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.
The conversation jokes about whether the character Vegeta from Dragon Ball should use hair loss treatments like finasteride or minoxidil. Some suggest he doesn't need it as his hairline hasn't changed for years, while others humorously propose treatments or question his hair genetics.
The user has seen no regrowth after 1 year and 2 months on finasteride, despite increasing the dose, and is inquiring about the potential of future treatments like verteporfin and gt20029 for hair regrowth.
Someone who is starting to experience hair loss and is considering multiple treatments, such as minoxidil, finasteride, dutasteride, and a hair transplant, to manage it. Replies provide advice on how to approach these treatments safely and effectively.
The relative strength of Pyrilutamide compared to RU58841 in terms of androgen receptor binding affinity. It has been noted that Pyrilutamide is 4x stronger than RU58841, with a higher binding affinity than DHT itself.
The user has been using finasteride, nizoral, microneedling, and recently added 3% peppermint oil to their hair loss treatment, experiencing regrowth similar to minoxidil. They suggest peppermint oil as a potentially effective, low-cost alternative or addition to minoxidil, with the added benefit of a pleasant smell and ease of use.
A user experienced severe side effects from using topical minoxidil sublingually, including muscle cramps, dizziness, and high potassium levels. They were advised to stop and seek medical help, emphasizing that topical minoxidil is not safe for ingestion due to its alcohol content.
A 39 year old female who has been taking finasteride for 1.5 months and is experiencing side effects such as muscle and butt shrinkage, and weight loss despite still having tight clothing. The user is seeking advice from those with knowledge of bodybuilding and hormones to help figure out the issue.
Treatments for hair loss, such as Minoxidil, finasteride, RU58841 and Eucapil; the legitimacy of RU58841 products; and safety concerns related to using RU58841.
The conversation discusses skepticism about Breezula, a hair loss treatment, with the consensus that it's not a miracle cure but a maintenance drug that may work well with finasteride. Some users report side effects from finasteride, like sexual dysfunction, while hoping for better results from Breezula or RU58841 without such side effects.
Some people avoid finasteride due to side effects but engage in unhealthy habits. Minoxidil and finasteride are common hair loss treatments, with varied side effect experiences.
A user speculates that a fast metabolism might affect the effectiveness of dutasteride for hair loss. Another user argues that drug response is unrelated to metabolism speed.
The conversation is about choosing a topical antiandrogen for hair loss, with options including RU58841, CB0301, Pyrolutamide, Alfatradiol, and Fluridil. Users discuss their preferences and reasons for selecting specific treatments.
A user shared their two-year progress using only topical finasteride for hair loss, recently adding keto shampoo, and plans for a hair transplant. They experienced regrowth and halted hair loss without using minoxidil due to side effects.
The conversation is about a user's nearly 4-month hair loss treatment regimen, which includes dutasteride every other day, 0.25ml minoxidil on the hairline once a day, and using a 1.5 mm derma stamp every two weeks. Some responses question the need to start multiple treatments simultaneously, while others comment on the visible improvement and the necessity to continue treatment for sustained results.
The conversation discusses whether long-term use of finasteride (Fin) is harmful to the liver, with various opinions on side effects and comparisons to other substances. Specific treatments mentioned include finasteride, minoxidil (Min), and RU58841 (RU).
A man shared his 6-month hair regrowth progress using 0.5mg of finasteride daily and recently increased the dose to 1mg. Users discussed the effectiveness of the treatment and shared their own experiences with hair loss treatments.
A user experiencing hair loss despite using finasteride, minoxidil, and tretinoin. They're considering trying dutasteride or shaving their head if the situation doesn't improve.
A user applied pyrilutamide for 6 months without hair regrowth and is considering stopping due to cost and lack of results. Another user suggests switching to finasteride, which is cheaper and has shown regrowth for them.
User decides to accept baldness due to mental health issues with finasteride. Others suggest considering hair systems, topical finasteride, or RU58841 as alternatives.