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GlossaryEndocrine Organ (Hormone-Secreting Organ)

specialized structure that releases hormones into the bloodstream

An endocrine organ, also known as an endocrine gland, is a specialized structure in the body that produces and releases hormones directly into the bloodstream. These hormones act as chemical messengers that regulate various physiological processes, such as metabolism, growth, and mood. Examples of endocrine organs include the thyroid gland, adrenal glands, and the pancreas.

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community I’m just Going to let Nature take its Course

in Chat 213 upvotes 1 year ago

The post and conversation are about a 23-year-old deciding to stop using finasteride for hair loss due to potential erectile dysfunction risks, sparking a debate about the benefits and side effects of hair loss treatments.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 56 upvotes 3 days ago

community How to know if shedding is from tren or minoxidil?

in Minoxidil 5 upvotes 7 months ago

The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

in Finasteride/Dutasteride 113 upvotes 1 year ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Solving Hair Loss with Research at MIT

in Research/Science 590 upvotes 1 month ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community A systematic bro-science review of DHT, 5AR, neurosteroids, sexual health and 5AR inhibitors

in Research/Science 37 upvotes 2 years ago

Hair loss treatments, specifically 5AR inhibitors, can impact neurosteroids and sexual health. The effects of topical fin/dut on tissue-specific DHT levels are unclear.

community Trestolone (MENT) as a nuclear treatment

in Treatment 99 upvotes 2 years ago

Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 7 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Please stop looking for a natural way to stop your hairloss

in Chat 369 upvotes 3 years ago

No natural way to stop hair loss, pharmaceuticals only option. Users discuss Minoxidil, Finasteride, natural remedies, and healthy scalp importance.

community 9 months of minoxidil , finasteride, spironolactone, estradiol

in Progress Pictures 64 upvotes 4 months ago

User shared progress pictures after 9 months of using minoxidil, finasteride, spironolactone, and estradiol for hair loss. Significant regrowth was noted, especially after starting estradiol.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 6 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community How all hormones affect our hair follicles. Not just DHT. Take a look at this paper. Prolactin, melatonin, cortisol, progesterone, testosterone and more

in Research/Science 126 upvotes 2 years ago

The conversation discusses various factors affecting hair loss, not just DHT, and mentions treatments like Minoxidil, finasteride, and melatonin. Some users report personal experiences with these treatments and hormone tests, while others speculate on the role of hormones like prolactin and cortisol in hair loss.

community Testosterone is 1600, would taking low dose anti-androgens be a viable treatment option for people who’s T spikes on DHT-blockers?

in Treatment 46 upvotes 1 year ago

The post and conversation are about the user's high testosterone levels and their worsening hair loss despite trying various treatments. They are considering using low doses of anti-androgens to lower their testosterone levels as a potential solution.

community Just under a year progress (topical fin/min .3/6%)

in Progress Pictures 614 upvotes 3 months ago

A user shared their positive experience with hair regrowth using topical finasteride and minoxidil, despite initial side effects. They are transitioning to oral finasteride and minoxidil for convenience and are optimistic about continued progress.

community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

in Transgender 127 upvotes 11 months ago

A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

community How did you get over the fear mongering of Fin/Dut?

in Finasteride/Dutasteride 62 upvotes 3 months ago

The conversation is about overcoming fear of finasteride/dutasteride for hair loss treatment. Users suggest starting with a small supply, noting side effects are rare and reversible, and emphasize personal comfort and confidence.

community how about progesterone cream?

in Research/Science 21 upvotes 6 months ago

Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

community 1 year results finasteride and minoxidil once daily nothing else

in Update 845 upvotes 4 weeks ago

The user experienced significant hair regrowth after one year of using finasteride, minoxidil, and Nizoral shampoo, with no side effects reported. They noted improved social interactions and emphasized the importance of consistency in treatment.

community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 271 upvotes 3 months ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 9 months ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community My Testosterone results before and after Finasteride

in Update 146 upvotes 3 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

community Creatine made all my high DHT symptoms return

in Research/Science 78 upvotes 2 weeks ago

Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

community My Finasteride story and ultimate dilemma, anyone else relate? What did you do?

in Finasteride/Dutasteride 2 upvotes 4 months ago

A user shared their experience with finasteride, noting improved hair thickness but reduced libido and erection issues. They stopped finasteride, saw a return of libido but also rapid hair loss, and are now considering using Cialis to manage sexual side effects while on finasteride.

community Dermatologist wants me to stop topical min+fin as a teen

in Minoxidil 7 upvotes 11 months ago

A 17-year-old has been using topical minoxidil and finasteride for hair loss but is advised by a dermatologist to taper off due to age concerns. Other users suggest continuing minoxidil but stopping finasteride until at least 18, and consulting a specialized pediatric dermatologist.

community Andrew Schulz stated he had been using a ‘’hair pill’’ for 15 years and it may have caused him infertility

in Satire 134 upvotes 1 year ago

The conversation discusses the potential link between hair loss treatment pills, specifically finasteride, and infertility. Users share their experiences and opinions, with some suggesting that finasteride can temporarily lower sperm count, while others argue that other factors like age and lifestyle could also contribute to infertility.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Kintor has announced the results for their human Phase I trials of GT20029

in Research/Science 257 upvotes 1 year ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.