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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

       133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Do you think clascoterone is overhyped

       14 upvotes 4 months ago
      Clascoterone is considered overhyped and not as effective as finasteride or dutasteride, but it may be useful as a supportive treatment in combination with other therapies. Users express skepticism about its effectiveness compared to clinical trials, with some suggesting it could be beneficial for those who cannot tolerate other treatments.

      community Update: Cbum's Transplant looks super good now

       614 upvotes 1 year ago
      Chris's hair transplant looks better, but the hairline is criticized for being too straight and unnatural. Some recommend using finasteride and minoxidil for maintenance.

      community 4 Month Hair Transplant Update: 3,153 Grafts (HLC, Turkey)

       5 upvotes 3 months ago
      A 35-year-old shared a 4-month update on their hair transplant of 3,153 grafts in Turkey, noting redness and uneven growth but hoping for improved density. They have been using finasteride for over 13 years and are optimistic about future results.

      community What is the best legit source of RU58841 in the UK?

      in Product  6 upvotes 2 years ago
      A user is seeking a trusted supplier for RU58841 in the UK, expressing doubts about their current source, rudirect, and considering Anagenic and receptorchem. They are asking for recommendations for other suppliers.

      community Where can I sign up for hair cloning clinical trials?

       4 upvotes 2 years ago
      The conversation is about a user interested in participating in hair cloning clinical trials due to their fine hair and previous positive experience with clinical trials. They are seeking information on how to volunteer for such trials.

      community The homeless crackhead protocol

       4487 upvotes 1 year ago
      The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.

      community My final attempt at creatine with fin

       43 upvotes 1 year ago
      Creatine may cause hair shedding and texture changes, with mixed user experiences. Combining creatine with finasteride doesn't always prevent these effects, possibly due to individual DHT sensitivity.

      community Desensitize Follicle Sensitivity to DHT?

       12 upvotes 3 weeks ago
      Hair follicles cannot be desensitized to DHT like allergies; treatments focus on reducing DHT levels or blocking its effects using methods like finasteride, GT20029, or PROTACs. Topical treatments like ceterizine and BPA application are also mentioned.

      community Cetirizine (Zyrtec), to help with inflammation.

       3 upvotes 2 years ago
      The user experiences an itchy scalp and finds relief using shampoo and Zyrtec, which helps with inflammation. They are unsure if the issue is related to histamines or seborrheic dermatitis.

      community RU58841 is great, super fast acting!

       6 upvotes 1 month ago
      RU58841 is praised for its fast-acting effects on hair regrowth, with the user also using finasteride, minoxidil, dutasteride, and GHKcu. Some users report side effects like chest pain, while others see positive results, but it's unclear which treatment is most effective due to multiple compounds being used simultaneously.

      community I mixed Pyrilutamide with a KB solution

       6 upvotes 4 years ago
      The user mixed Pyrilutamide with a KB solution and noticed some undissolved powder, questioning if more shaking or liquid is needed. They use Pyrilutamide from Anagenic.

      community Will you try clascosterone when it gets released?

      in Treatment  14 upvotes 7 months ago
      People are interested in trying clascosterone (Breezula) for hair loss, especially those who are too young for finasteride. Some users express concerns about the cost and prescription requirements, while others discuss alternatives like RU58841.

      community Does it work? Maneup GHK-Cu hair growth serum

       10 upvotes 2 years ago
      The conversation is about the effectiveness of Maneup GHK-Cu hair growth serum, a topical treatment for hair loss. The user is considering trying it but is skeptical due to issues others have had with DIY injections of a similar substance.

      community I'm losing it with RU58841 lol. Any fellow RU user help is appreciated.

       8 upvotes 2 months ago
      The user is struggling with the high cost of RU58841 and is seeking cheaper bulk sources, considering options like Carolina Chemical. Other users discuss alternative treatments like finasteride, minoxidil, and dutasteride, with mixed experiences on effectiveness.

      community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?

       46 upvotes 1 month ago
      Clascoterone is nearing regulatory submission as a potential new treatment for androgenetic alopecia, with positive Phase III results, while discussions continue about other treatments like PP405, minoxidil, and finasteride. Some users express excitement for clascoterone and Breezula, despite concerns about the effectiveness and practicality of topical treatments.

      community Anyone managed to get clascoterone 5% in the uk?

       4 upvotes 3 months ago
      The conversation is about finding clascoterone 5% or other effective anti-androgens for hair loss in the UK, with openness to purchasing from outside the UK. A suggestion was made to visit Dublin, where research on the treatment is ongoing.

      community 2 month hair transplant update - HLC Ankara - How we looking?

       3 upvotes 5 months ago
      A 35-year-old shared a 2-month update on their hair transplant of 3153 grafts, noting redness, itching, and some pimples, while using finasteride for over 12 years to maintain hair. Users discussed the effectiveness and timing of starting finasteride, with some suggesting consulting a doctor for young individuals considering the treatment.

      community new way to activate stem cells to make hair grow

       42 upvotes 7 years ago
      Stem cell-related treatments and drugs like RCGD423 and WAY are being tested for hair growth. Clinics are conducting tests on patients who haven't had previous treatments.

      community Clascoterone full results 2026

       7 upvotes 2 weeks ago
      Clascoterone results are anticipated to be released in fall 2026, possibly at the EADV conference. Users express skepticism and humor about the release date.

      community 3-year fin/min plateau broken? Crown progress update (May 2025 – Present)

       50 upvotes 1 month ago
      The user experienced significant hair regrowth after adding GHK-Cu injections to their existing treatment of topical finasteride and oral minoxidil, breaking a long plateau. They are curious if others have had similar experiences with adding new treatments to their regimen.

      community PP405 is out for sale on everychem.

       94 upvotes 1 year ago
      PP405 is suspected to be a scam, with users doubting its legitimacy and effectiveness. Many recommend using proven treatments like finasteride and minoxidil.

      community Any clinical study on cysteine alone for hair loss?

       6 upvotes 1 year ago
      The conversation discusses the lack of clinical studies on cysteine alone for hair loss, with the original poster already using medications like Minoxidil and finasteride. Suggestions include trying 2ddr as a growth stimulant, though concerns about side effects like gas are mentioned.

      community RU58841 3 Month Results while abusing PEDs

       29 upvotes 8 months ago
      RU58841 helped regrow hairline without side effects for a bodybuilder using PEDs. The treatment included RU58841, finasteride, minoxidil, GKH-Cu, microneedling, and HGH.

      community My Idea for a possible new hairloss treatment

       53 upvotes 6 years ago
      Exploring a potential hair loss treatment using the enzyme AKR1C2 to locally reduce DHT levels. Challenges include enzyme delivery through the skin and high production costs, with gene therapy or stem cells suggested as future alternatives.