Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
This conversation discusses the potential benefits of using oral minoxidil and finasteride to treat hair loss, with some users sharing their own experiences in taking the medications. Others express concerns about the safety of these treatments.
A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.
Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.
A user's progress with using Minoxidil 5% twice daily, dermarolling 1.5mm once per week and ketoconazole 2% shampoo for 2.5 months. Other users have suggested that the user should also use finasteride in order to maintain their results.
A user shared their positive experience of embracing baldness after years of trying treatments like Minoxidil and finasteride. They found happiness and confidence by shaving their head, despite some social challenges, and encouraged others to focus on their attitude and seek therapy if needed.
A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.
A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.
This user reported successful hairgrowth after using 1mg finasteride and 1ml of 5% minoxidil daily for a year, prompting other users to suggest additional treatments such as microneedling. The before picture was taken prior to the use of these treatments.
The user follows a hair loss treatment routine including Propecia, oral minoxidil, ketoconazole, and plans to switch to dutasteride. They also focus on lifestyle changes, dietary supplements, and are considering laser therapy.
Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hairgrowth.
The conversation discusses switching from finasteride to dutasteride for hair loss treatment, with mixed experiences regarding shedding and effectiveness. Some users also mention using minoxidil and RU58841 alongside these treatments.
RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
Switching from finasteride and topical minoxidil to oral minoxidil and dutasteride worsened hair condition, leading to frustration and heart issues, prompting a return to topical treatments and the addition of tretinoin. Patience and consistency are advised, as these treatments can take years to show results, and abrupt changes may cause shedding.
The conversation discusses the effectiveness of RU58841 for hair loss compared to pyrilutamide, which failed to show significant hair regrowth in trials. Some users report personal side effects with RU58841 and question the criteria for success in hair loss treatments.
The regimen for hair loss includes topical finasteride, clascoterone, tretinoin, minoxidil, oral saw palmetto, beta-sitosterol, vitamin D, microneedling, and anti-fungal shampoo. Expected benefits are increased hairgrowth and density, with considerations for potential skin irritation and interactions between treatments.
The user believes neck tension and poor posture contribute to hair loss, noticing improvements with yoga and muscle relaxation. Replies suggest androgenic alopecia as the cause and recommend exercises.
A 36-year-old considering a fourth hair transplant is advised to either shave his head or use a hair system due to poor results from previous transplants and late medication use. He plans to consult top surgeons and adjust his current treatments, including finasteride and minoxidil.
TDM-105795 showed promising hairgrowth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.
Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hairgrowth results in non-clinical studies. ET-02 demonstrated significantly more hairgrowth compared to Minoxidil.
A user's progress with their hair loss treatment, which includes finasteride and nizoral, as well as the potential for using minoxidil; other users providing advice based on their own experiences; and others discussing how buzz cuts can make diffuse thinning look worse than it is.
GT20029 showed significant hairgrowth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.
The conversation discusses using T3 (triiodothyronine) as a topical treatment for hairgrowth, with some users noting it showed promising results in studies but lacked follow-up. Users express interest in trying T3 due to its potential effectiveness compared to Minoxidil.
User noticed hairgrowth after 1.5 months using Fin, Min, stemoxydine, dermarolling, nizoral, and scalp massage. Others commented on promising results and potential improvement in 6 months.
JW0061 shows superior hairgrowth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-catenin pathway is crucial for hairgrowth, and JW0061 activates this pathway effectively.
The conversation discusses taurine supplements for hairgrowth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.
The conversation discusses a new hairgrowth treatment that showed a 14 hairs/cm2 increase in a trial, with mixed opinions on its effectiveness and potential cost. Some users are hopeful about combining it with existing treatments like oral minoxidil for better results.
KOSHINE826 is a new anti-hair loss and hairgrowth solution that claims to effectively control oil, reduce hair fall, and promote real hairgrowth. It targets androgenetic alopecia by inhibiting DHT and has shown promising results in clinical trials.