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GlossaryHair Follicle Mesenchymal Stem Cells (Hair Follicle MSCs)

cells in hair follicles that can become various tissue types

Hair Follicle Mesenchymal Stem Cells (HF-MSCs) are a type of stem cell found within the hair follicle that have the ability to differentiate into various cell types, including those that form skin, hair, and connective tissues. These cells play a crucial role in hair growth, wound healing, and tissue regeneration, making them a significant focus in regenerative medicine and treatments for conditions like alopecia.

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community New and Interesting HairLoss Studies/Papers/Reviews

TerpsandCaicos in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Microneedling and aloe vera to recruit stem cells.

capilluscare in Chat 11 upvotes 1 year ago

Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.

community I am not losing my hair (yet) and do not think I will soon, but I am a pre medicine major who has an obsession over stem cells and want to share something with you all. Your future is brighter than you think.

hoodoomoovoo 19 upvotes 7 years ago

User hoodoomoovoo discusses their interest in stem cell research and its potential for hair loss treatment. They share links to studies and mention ongoing trials, expressing optimism for a future solution to hair loss.

community 4 weeks on oral fin 1mg daily and keto shampoo 2x week. Progress?

alwayz-a-beginner in Progress Pictures 100 upvotes 11 months ago

A 35-year-old male is using oral finasteride and ketoconazole shampoo for hair loss and is unsure about seeing improvement after 4 weeks. Suggestions include continuing the current treatment for at least 6 months before expecting results, and considering adding minoxidil to the regimen.

community New potential hair loss treatment (news release)

wrassman in Treatment 186 upvotes 4 years ago

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

community Pyrilutamide (has anyone seen improvements)

Combfromhell in Research/Science 18 upvotes 2 years ago

Pyrilutamide and its effectiveness for treating hair loss, with advice from other users cautioning to wait at least 6 months before expecting any results. Treatments discussed include finasteride and minoxidil.

community pictures before I started pyrilutamide (repost)

Automatic-Law-3612 in Progress Pictures 124 upvotes 1 year ago

Automatic-Law-3612's progress with hair loss treatments, including topical finasteride, topical dutasteride, minoxidil and pyrilutamide. They have been using these products for two weeks and noticed baby hairs in their temples getting longer.

community My eyelashes and eyebrows on oral min

Crazy-Signature930 in Progress Pictures 302 upvotes 1 year ago

User Crazy-Signature930 shares progress on oral minoxidil for eyelashes and eyebrows. Others comment on the impressive results and ask about side effects and duration of use.

community Are baby hairs growing on fin and min?

Riolite55 in Is this regrowth? 125 upvotes 9 months ago

The conversation discusses whether baby hairs observed after using finasteride and minoxidil will grow into terminal hairs, with mixed experiences and opinions shared on the effectiveness of these treatments for hair regrowth. Some users report positive results, while others are skeptical about the potential for significant change.

community Hello everyone! I just wanted to show you guys my hair transplant result so far. I actually really liked it. And I recommend a hair transplant for everyone who suffering from baldness. I'm 37 and I feel regret that why I didn't have a hair transplant till that time.

SolutionDifficult127 in Treatment 611 upvotes 3 years ago

A user's successful hair transplant result, and other users recommending finasteride to maintain it.

community HLT Megathread on HMI-115 (key takeaways in comments)

tired45453 in Research/Science 38 upvotes 2 years ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community One year of dudasteride and minoxidil daily

seloeren in Progress Pictures 1 year ago

This conversation details the impressive one year progress of a user's hair loss treatment, which included taking daily doses of dutasteride and minoxidil. Other users shared their own experiences with similar treatments, such as not having any shedding when starting, or having an oily scalp that improved significantly.

community Survived First Monte. Shedding is real

Emotional-Owl-3528 in Progress Pictures 370 upvotes 10 months ago

The user is treating hair loss with 1mg finasteride every other day, daily topical minoxidil, and weekly derma rolling, and is considering using hair fibers for special occasions. There is a discussion about the initial shedding phase of minoxidil treatment and the importance of consistent photo conditions to track progress.

community 20yo, dutasteride and minoxidil aren’t working

g-becker in Finasteride/Dutasteride 117 upvotes 5 months ago

A 20-year-old reports worsening hair loss despite using dutasteride and minoxidil, and considers a hair transplant. Users suggest continuing treatments, trying microneedling, ketoconazole shampoo, switching to finasteride, or adding tretinoin.

community 4 month progress update. hair transplant, 1000 grafts each temple, plus 1000 grafts on crown (3000 total). I take oral oral dutasteride + topical minoxidil daily since the surgery

polypancake in Progress Pictures 28 upvotes 1 year ago

A hair transplant surgery involving 3000 grafts and the daily use of oral finasteride and topical minoxidil for four months since that procedure.

community How much time does it need to pass for a hair follicle to be considered "unrecoverable"?

eljijazo08 in Chat 26 upvotes 10 months ago

A user who experienced hair loss and stopped finasteride 4.5 years ago is considering restarting treatment with finasteride and oral minoxidil, questioning if their hair follicles are still recoverable. Responses suggest that hair follicles may not die and can potentially be revived even after many years, with some users sharing personal success stories using treatments like minoxidil, finasteride, microneedling, and RU58841.

community Switched from topical to oral finasteride and slowly Withdrawal my hairs from topical minoxidil, and added xl hair serum.

Automatic-Law-3612 in Progress Pictures 1 upvotes 10 months ago

The user switched from topical to oral finasteride, reduced their use of topical minoxidil, and started using XL hair serum with a mesogun injector. They are seeing hair regrowth even with a lowered dose of minoxidil and are considering oral minoxidil for the future.

community HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)

Slight_Gap_7067 in Progress Pictures 118 upvotes 5 months ago

User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.

community Hair Cloning, Trials were supposed to begin 2020-2021

AlphaBetablue in Technology 48 upvotes 4 years ago

The conversation discusses hair cloning trials expected to start in 2020-2021 and mentions concerns about potential delays due to the Coronavirus. Treatments like Minoxidil, finasteride, and RU58841 are referenced.

community My somewhat nuclear Hair loss prevention procotocol

Traditional_Run_6940 in Treatment 6 upvotes 1 year ago

A 21-year-old male shared his extensive hair loss treatment protocol, which includes Dutasteride, RU58841, Ketoconazole shampoo, oral Minoxidil, pyrilutamide, MK677, dermastamping, and castor oil, and reported improved hair regrowth and overall well-being. He has experienced no side effects and has also improved his diet and lifestyle.

community Possible topical option for preventing BDNF-related hair loss

Wearethemusicmaker in Research/Science 7 upvotes 1 year ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community Balding at such young age effed me up terribleably and it's getting worse

BleachPuff in Shaved/buzzed 181 upvotes 6 months ago

An 18-year-old is experiencing worsening hair loss, feeling isolated, and considering treatments like Minoxidil and finasteride. Others suggest seeing a dermatologist to determine the cause and potential treatments.

community Almost 22M. Finasteride only. A little over a year's worth of progress

throwawayacc1289ount in Progress Pictures 383 upvotes 6 months ago

A 22-year-old male shared his one-year progress using finasteride for hair loss, showing significant improvement after 4-6 months. He experienced initial shedding but saw regrowth starting around the 4-month mark.

community 3 months of minoxidil foam. No fin or derma rolling

Donsaholic in Minoxidil 700 upvotes 2 years ago

This user has had success with Minoxidil foam, achieving significant hair growth in three months without using finasteride or derma rolling. They are considering incorporating a DHT reducing strategy such as finasteride in the future.

community New Treatments, and a Huge Group Buy with Lots of Research

jumpmanmm in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community Stemoxydine, anyone use it, is it a nice add-on?

Willing-Tomatillo-16 in Minoxidil 14 upvotes 2 years ago

Treatments for hair loss (Dutasteride, Finasteride and Minoxidil) and the potential benefits of adding Stemoxydine to the treatment.

community 2 months progress on Finasteride

crymeariveraight in Progress Pictures 216 upvotes 1 year ago

A user reported hair thinning, started using finasteride, and experienced a significant initial hair shed followed by noticeable hair regrowth after 2 months. Some responders questioned the rapid progress, while another noted that finasteride typically increases hair density by 16% after 2 years.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

Zeweny in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community What's up with everyone microneedling 1.5 mm per week?

Ok-Seaworthiness-913 in Microneedling 52 upvotes 1 year ago

The conversation is about microneedling for hair loss. The conclusion is that there are differing opinions on the depth and frequency of microneedling, with some studies suggesting positive results with 1.5mm depth once a week, while others prefer lower depths and less frequent sessions.

community Thoughts on Pantostin Alfatradiol?

jimbojangot in Treatment 10 upvotes 3 years ago

User started using Pantostin Alfatradiol after watching haircafe on YouTube and noticed thicker hair. They wonder why it's not more popular, as it's a 5α-reductase inhibitor with a different mechanism than minoxidil.