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      community I think I might have cured my hairloss

       17 upvotes 10 years ago
      The user experienced severe dandruff and hair loss, trying various treatments including oils, vitamins, and minoxidil. They found success by simply dampening their scalp with water twice a day, which improved their hair's appearance and eliminated psoriasis.

      community If RU58841 is such an effective anti androgen

      in Research/Science  47 upvotes 10 months ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community Update: 4 Month progress on Fin/Min plus dermaroller

      in Progress Pictures  559 upvotes 10 months ago
      A user shared a 4-month update on their hair regrowth progress using finasteride, minoxidil, a dermaroller, ketoconazole shampoo, multivitamins, and biotin, and received positive reactions and inquiries from others. They also mentioned lifestyle changes such as quitting creatine, alcohol, and smoking, which may have contributed to their success.

      community Anyone else crying themselves to sleep because of the pyrilutamide fail?

      in Technology  41 upvotes 11 months ago
      The conversation is about disappointment with pyrilutamide's performance as a hair loss treatment, with some users expressing interest in other treatments like Verteporfin, GT20029, and RU58841, while others suggest sticking with established treatments like finasteride or dutasteride.

      community Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early

      in Finasteride/Dutasteride  247 upvotes 1 year ago
      The conversation discusses the effectiveness of finasteride and dutasteride in treating hair loss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.

      community RU58841 alone vs. with Fin / Dut

      in Finasteride/Dutasteride  11 upvotes 1 year ago
      RU58841 combined with finasteride or dutasteride is more effective than RU58841 alone for hair loss. Users suggest combining these with minoxidil and microneedling for better results.

      community One year of dudasteride and minoxidil daily

      in Progress Pictures 1 year ago
      This conversation details the impressive one year progress of a user's hair loss treatment, which included taking daily doses of dutasteride and minoxidil. Other users shared their own experiences with similar treatments, such as not having any shedding when starting, or having an oily scalp that improved significantly.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  41 upvotes 1 year ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Why only the top of the head?!

      in Chat 2 years ago
      Why the top of the head is affected by hair loss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  207 upvotes 3 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2446 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community Help with Routine for 50 year old Black Woman

      in Female 4 years ago
      A 50-year-old Black woman with alopecia areata and traction alopecia is seeking a science-based hair loss routine. Current treatments include spearmint tea for DHT levels and considering PRP.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  64 upvotes 4 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community Redensyl (The Ordinary Serum)

      in Treatment  21 upvotes 4 years ago
      Redensyl, a hair loss treatment that has been claimed to be 80% more effective than minoxidil, but users have not experienced any results from using it.

      community 23M, been on 1.25mg generic Finasteride for 8 months now

      in Is this regrowth?  387 upvotes 2 months ago
      A 23-year-old male has been using 1.25 mg generic finasteride daily for 8 months and is seeing significant hair regrowth, particularly in the crown area. He is considering adding minoxidil to his regimen but is unsure if the improvement is due to the medication or just longer hair.

      community My boy Saul Goodman was on Minoxidil tabs too

      in Satire  1891 upvotes 3 months ago
      Saul Goodman was humorously depicted using high doses of minoxidil, finasteride, and spironolactone for hair loss. The conversation jokes about the unrealistic dosages and their potential side effects.

      community Watching my younger brother bald hurts so much.

      in Treatment  264 upvotes 3 months ago
      A 19-year-old is distressed about his 17-year-old autistic brother's hair loss, projecting his own insecurities despite being on finasteride and dutasteride. Replies suggest the brother might not care about balding, and the poster should address his own issues.

      community Treating MPB while dealing with seborrheic dermatitis?

      in Treatment  8 upvotes 4 months ago
      The user is seeking advice on treating male pattern baldness (MPB) while dealing with seborrheic dermatitis, specifically asking about the use of finasteride (Fin) and minoxidil (Min). They are concerned about side effects and are looking for recommendations to improve overall hair thickness, especially on the crown.

      community (Serious) Updates and discussion, new treatments in development

      in Treatment  7 upvotes 5 months ago
      Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.

      community What's the deal with Zinc and DHT?

      in Chat  47 upvotes 6 months ago
      The conversation discusses the conflicting information about Zinc's effect on DHT and its role in hair loss. It mentions that Zinc can act as a 5AR inhibitor at high doses but may increase DHT if taken to correct a deficiency, and highlights the importance of nutritional balance for hair health.

      community So is GT20029 available on the grey market anywhere?

      in Treatment  17 upvotes 7 months ago
      The conversation discusses the availability of GT20029, a new topical hair loss treatment with fewer side effects than Minoxidil or finasteride. Users suggest using finasteride to preserve hair until GT20029 becomes available.