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      community PP405 (Non) Update - Feb 2025

       36 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community My two months experience with RU58841

       43 upvotes 4 years ago
      The conversation discusses using RU58841 for hair loss, with OP applying a 5% premixed solution from Receptorchem daily. Users express skepticism about the rapid results and inquire about other treatments and costs.

      community How long are Pelage going to milk the phase 2a results of PP405?

       21 upvotes 8 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.

      community Lowest Effective RU58841 Dose?

      in Treatment  4 upvotes 1 year ago
      RU58841 is discussed as a hair loss treatment, with users considering lower doses like 2.5% to reduce costs. Some users suggest that if already blocking DHT, lower doses might still be effective unless there's high sensitivity to DHT.

      community Crazy 6 month oral minoxidil and GHK-CU transformation

       266 upvotes 2 months ago
      The user shared a 6-month update on using oral minoxidil and GHK-Cu for hair regrowth, noting significant improvement and increased confidence. Some commenters questioned the authenticity of the transformation, mentioning visible hair fibers, while others discussed the role of DHT blockers and religious perspectives.

      community Now i want to see if this DHT survives

      in Treatment  33 upvotes 1 year ago
      The conversation discusses using minoxidil, finasteride, spironolactone, and RU58841 for hair loss treatment. Users share experiences with these treatments, noting side effects and varying effectiveness.

      community RU58841 legit source from europe and china

      in Product  1 upvotes 2 years ago
      A user is seeking advice on purchasing RU58841 from Biolab Shop in Poland and is looking for trustworthy sources that deliver to Germany from Europe or China. They are interested in the product's composition and user experiences.

      community Sharing my hair regworth and treatments for the last 15 months

       242 upvotes 2 weeks ago
      The user experienced significant hair regrowth and improved scalp condition using GHK-Cu peptide, minoxidil, and finasteride over 15 months, with GHK-Cu alone showing noticeable results before adding the other treatments. They reported some side effects like scalp irritation and sleep disturbances but found the combination of treatments satisfactory and confidence-boosting.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 6 months ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community The Theory of BURN THE SCALP. !! NEW UPDATES¡¡¡

      in Update  124 upvotes 1 year ago
      The conversation discusses a user's experiment with using hot water and a dermastamp to reduce hair loss, improve dandruff, and promote new hair growth. The user advises caution and mentions not sharing photos until more progress is visible.

      community Anyone tried GHK-CU for hair loss?

      in Treatment  6 upvotes 1 year ago
      The conversation is about using GHK-Cu, a copper peptide, for hair loss treatment. Users discuss their experiences, dosages, and additional benefits like improved skin and energy.

      community 3/9/26 to 7/5/26 results - Oral Min + Fin + GHK-Cu (SubQ)

       61 upvotes 2 months ago
      The user reported positive results in hair density and skin improvement using a combination of oral Minoxidil, Finasteride, and subcutaneous GHK-Cu. They experienced less shedding with oral Minoxidil compared to topical and noted significant skin benefits from GHK-Cu.

      community 10 months in and in the middle of a huge shed

      in Progress Pictures  10 upvotes 5 months ago
      The user is experiencing a significant hair shed at 10 months but sees improvement compared to 4 months ago. They are using Hims products, Feel Confident shampoo, Nizoral, a light therapy cap, and The Ordinary hair serum.

      community Musely s Exosome formulation looks interesting

       14 upvotes 1 year ago
      Exosomes, cetirizine, melatonin, latanoprost, and caffeine are discussed as potential hair loss treatments. There is skepticism about the effectiveness of exosomes, especially in topical form, but some users report positive results.

      community Today, The DHT Attacked

       41 upvotes 8 years ago
      The conversation humorously discusses the effects of DHT on hair loss, with references to treatments like finasteride and RU58841. Users share exaggerated stories about DHT's impact, highlighting its negative reputation.

      community Making PG free solution at home

       1 upvotes 2 years ago
      A user wants to make a solution for RU58841 and finasteride powder using only glycerin and asks if ethanol is necessary. They are seeking advice on whether glycerin alone is sufficient.

      community What solution to use for RU58841?

       1 upvotes 3 years ago
      The post is about using different solutions for RU58841, a treatment for hair loss. The user is asking for opinions on the effectiveness of different vehicles and dosages.

      community Expectations control for SCUBE3

       20 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community The dose dependent nature of the cardiac effects RU58841

       5 upvotes 8 months ago
      Reducing the dose of RU58841 from 25mg to 7.5mg topically helped minimize heart palpitations. Users discussed the cardiac effects of RU58841 and minoxidil, noting that no treatment is completely free of side effects.

      community How much shedding on dutasteride is too much? Really stressed out.

       5 upvotes 3 years ago
      The user experienced significant hair shedding after switching from finasteride to dutasteride, which was attributed to telogen effluvium likely worsened by stress and an abrupt medication change. The user returned to finasteride and started oral minoxidil, resulting in hair recovery to 80-90% of its original state.

      community Exosomes 2 months before and after

       7 upvotes 1 year ago
      Exosomes are being discussed as a potential hair loss treatment, with some users skeptical about their effectiveness and stability. There is interest in different types of exosomes, including those derived from centella asiatica, and comparisons are made to other treatments like finasteride.

      community Possible solution: 2.5mg DUT for everyone

       14 upvotes 1 year ago
      A user is experimenting with creating a DIY oral Dutasteride solution using raw powder, MCT oil, and Vitamin E to reduce costs. Others discuss their experiences with similar methods and the challenges of sourcing and testing Dutasteride.

      community Blow dryer, sea salt spray, mousse, texture powder

       5 upvotes 2 weeks ago
      Using a blow dryer, sea salt spray, mousse, and texture powder can significantly increase hair volume. These products can improve hair appearance quickly and easily.

      community how does a shed stop? Is it gradual or sudden?

      in Chat  5 upvotes 1 month ago
      Hair shedding can be gradual and varies daily, with some noticing less shedding over time. Treatments like Minoxidil, finasteride, and RU58841 are not mentioned in this conversation.