Topical finasteride absorption starts almost instantly, but the exact time needed for full absorption is unclear. Users suggest it may not need to stay on all day.
Pelage Pharmaceuticals announced positive Phase 2a trial results for PP405 in hair loss therapy. The conversation discusses the delay in publishing full results and the need for further trials and approvals.
The user experienced noticeable hair growth after 9 months using oral dutasteride, with full results expected in 20-24 months. They prefer oral treatments over topical minoxidil due to convenience.
User asks if washing hair or using hair fibers after minoxidil dries is okay and if dry scalp means full absorption. Some doctors and sources say 50-75% absorption occurs after an hour.
The user switched from finasteride to oral dutasteride and is assessing hair regrowth progress after 5 months, with some users noting visible improvement in density and regrowth. The user is advised to continue with dutasteride as it may take over two years for full effects.
The user shared progress pictures showing significant hairline growth over 2.5 years using finasteride, minoxidil, and red ginseng water. They reported no side effects and noted thicker, curlier hair with almost full recovery in the crown area.
The user has been using oral finasteride and minoxidil for 5-6 months to stop hair loss and is considering a hair transplant. It is suggested to wait 18-24 months for full effects before considering a transplant, with Turkey and Thailand mentioned as cheaper options.
After four months of using minoxidil, finasteride, tretinoin, and microneedling, fine white fuzz appeared on bald patches. There is uncertainty if this fuzz will develop into full hair.
The user experienced improved hairline results after 11 months on finasteride, with no significant side effects except temporary nipple sensitivity. They are considering adding minoxidil for better results but are waiting for full effects from finasteride.
Finasteride caused depression and suicidal thoughts in OP's husband, leading him to stop the medication. He is seeing a doctor for a full hormone panel and psychiatric referral to address these issues.
The user is concerned their hair transplant with 1500 grafts may have failed after 10 months, despite using 5% topical minoxidil and 1mg oral finasteride since 2023. Others suggest waiting until 18 months for full results and considering additional treatments like PRP or dutasteride.
A 22-year-old has been using oral dutasteride and minoxidil for a year to prevent hair loss, experiencing some thinning at the temples but maintaining a full head of hair. The user increased the dosage after consulting a dermatologist and is considering adding ketoconazole shampoo for additional scalp DHT suppression.
A user shared their experience with hair loss treatment using dutasteride for 2 years and oral minoxidil for 1.5 years, noting some regrowth but not full recovery in temple areas. Suggestions included microneedling, topical minoxidil, and considering a hair transplant for further improvement.
The user experienced noticeable hair regrowth and improved hair texture after 6 months on 0.5mg oral finasteride and 2 months on 1.25mg oral minoxidil, with no side effects. They are optimistic about further improvements as the minoxidil takes full effect.
Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.
The user is using dutasteride and minoxidil for hair loss and noticed new hair growth after initially thinking there was no progress. Encouragement was given to continue the treatment as it takes time to see full results.
The conversation humorously discusses hair loss, focusing on the envy of an older man, Massimo Cacciari, who has a full head of hair. Treatments mentioned include finasteride, minoxidil, RU58841, and hair transplants, with some users expressing dissatisfaction with baldness and considering various solutions.
The user reported progress in hair regrowth after 3 months using finasteride, biotin, and minoxidil, with no sexual side effects. Most responses noted significant improvement, encouraging continued use for full results.
The user reports improved crown hair regrowth after 5 months of using Dutasteride and Minoxidil, but minimal change in the front/temples. Others suggest waiting 12-18 months for full results and note that temple regrowth is typically slower.
The user experienced noticeable hair thickening and new growth after two months using a topical solution of minoxidil and finasteride. Continued improvement is expected, with potential for a full head of hair after further treatment and possibly a transplant.
PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.
Finasteride and dutasteride are discussed as preventative treatments for hair loss, with some advocating for early use and others concerned about side effects, especially before full maturity. Many regret not starting these treatments earlier due to their effectiveness in preventing or slowing hair loss.
The conversation discusses the effectiveness and potential side effects of using a minoxidil, finasteride, and biotin combination pill for hair loss, comparing half-dose (0.55mg Fin, 2.5mg Min, 0.5mg Biotin) to full-dose (1.1mg Fin, 5mg Min, 1mg Biotin). The user is considering whether to increase to a full dose after starting with a half dose.
The FDA will now require only one clinical trial for drug approval, potentially speeding up the release of hair loss treatments like PP405. Pelage is expected to present full results of PP405 Phase 2a trials and move to Phase III in mid-2026.
The user has experienced hair loss stabilization with dutasteride and oral minoxidil but is considering adding RU58841 for potential regrowth. Another user advises that it may take up to 36 months for full results with dutasteride and warns of possible side effects with RU58841.
The user is using 1 mg finasteride daily, Rogaine foam once a day, and Nizoral 2-3 times a week for hair regrowth. Progress is visible, but full effects of finasteride may take 12-18 months, and patience is advised.
A 24-year-old experienced improved hair growth using 5% minoxidil, 1 mg finasteride, and dermastamping, but faced side effects like low libido and mild erectile dysfunction. They plan to reduce finasteride dosage after full results and may consider a hair transplant if thinning recurs.
Finasteride and minoxidil help maintain hair and slightly improve hairlines but are less effective at regrowing hair in bald areas, often needing a hair transplant for full restoration. Many users report no side effects and wish they had started treatment earlier.
A 31-year-old Australian had a successful hair transplant in Turkey for $10,000 AUD, using minoxidil and finasteride to combat hair loss. He now has a full head of hair, increased confidence, and continues using finasteride with occasional minoxidil.
Finasteride and minoxidil significantly improved a user's hair loss, starting at age 17, leading to a full head of hair by age 19 without side effects. The user prefers oral minoxidil over topical due to better results and less hassle.