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      community 1 year on fin/min. This is your reminder to power through!

       1217 upvotes 1 year ago
      The user experienced significant hair regrowth after one year of using oral minoxidil (2.5mg) and oral finasteride (1mg), with no side effects except initial shedding. The user noticed thicker eyebrows and beard, and the hairline improved with baby hairs, but the hair quality differs from the rest of the head.

      community Is RU58841 really a game changer ?

       30 upvotes 4 years ago
      Topical finasteride and minoxidil show some hair regrowth, but hair loss persists. RU58841 is considered effective by some users but is not well-tested, with potential side effects; it may be used alongside finasteride for better results.

      community Thinking about signing up for the setipiprant clinical trials

       5 upvotes 9 years ago
      The conversation discusses hair loss treatments, with the original poster considering joining a clinical trial for setipiprant after experiencing side effects from finasteride and disinterest in minoxidil. Some users express skepticism about setipiprant's effectiveness, while others encourage participation in the trial for potential benefits.

      community Chinese Research Chemicals You Suggest

      in Research/Science  3 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically RU58841, with mentions of side effects from finasteride and dutasteride. Alternatives like Pyri, KX-826, and Breezula are also mentioned.

      community Very high free testosterone on dut…

       9 upvotes 6 months ago
      The user has high free testosterone and is still experiencing hair loss despite taking dutasteride and oral minoxidil for over three years. They are considering adding a topical anti-androgen like RU58841.

      community RU58841 vs. KX-826 vs. CB-03-01

       16 upvotes 3 months ago
      RU58841 shows the strongest results despite weaker binding affinity, while KX-826 and CB-03-01 are more expensive and have minimal side effects. RU58841 is considered effective but has potential health risks if ingested; users report positive outcomes with RU58841 and finasteride.

      community Completed my Clascoterone study, updating as promised, no change

       14 upvotes 1 year ago
      The user completed a Clascoterone study with no observable changes in hair loss and plans to try microneedling and Minoxidil next. They will microneedle weekly and apply Minoxidil twice daily, except on the night of microneedling, and compare results after six months.

      community Fin/Min - Just over 2 months progress (2/26 - 4/29)

       53 upvotes 1 year ago
      The user is using finasteride, minoxidil, dermastamp, nizoral, biotin, fish oil, and zinc magnesium B-6 for hair loss treatment. They report healthier hair and are hopeful for further regrowth.

      community Oral fin 1mg, oral min 2.5 mg - 18 months

      in Progress Pictures  111 upvotes 1 month ago
      A 27-year-old male shared progress on hair density improvement after 18 months of using oral finasteride (1mg) and oral minoxidil (2.5mg) daily, with no side effects reported. He also reduced alcohol consumption and improved overall health, noticing results around 8 months in.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

       133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community high estrogen levels after 10month fin

       9 upvotes 3 years ago
      A user experienced high estrogen levels after 10 months of taking 1mg oral finasteride but is happy with hair regrowth. They are considering switching to topical finasteride and are also taking DIM and Zinc supplements.

      community is Oleanic acid a DHT blocker ?

       4 upvotes 2 years ago
      A user is experiencing hair thinning and is using a peptide with oleanic acid as a DHT blocker, along with minoxidil, while waiting for topical finasteride. They plan to use a combination of minoxidil, finasteride, dermastamp, ketoconazole, and scalp massages, but are advised to stick to proven treatments like finasteride and minoxidil.

      community Got my bloodwork results, need guidance!

      in Update  1 upvotes 1 year ago
      An 18-year-old male with hair loss is considering starting finasteride but is concerned about potential side effects like gynecomastia due to his prolactin levels. He seeks guidance on whether his bloodwork indicates it's safe to begin treatment.

      community It’s all about the stem cells…

       53 upvotes 4 years ago
      Hair loss is linked to the loss of stem cells in hair follicles, and potential treatments include gene editing and microneedling. Discussions also mention using Minoxidil, finasteride, and dermarolling to improve hair growth.

      community Can one of you smarty pants explain the PP405 results? Why did they choose to highlight that 31% had 20% increase in density? What about the other 69%? What about other ±% in density? Why is this considered a great result? Thanks.

       13 upvotes 10 months ago
      PP405 shows promise in reactivating dormant hair follicles, with 31% of users experiencing a 20% increase in hair density in a short period. It may work faster than minoxidil and without side effects, but its long-term effectiveness is still uncertain.

      community Minoxidil permanent face changes?

       4 upvotes 4 years ago
      Excessive use of topical minoxidil led to unwanted facial changes and side effects. The user plans to switch to oral minoxidil with microneedling for hair regrowth.

      community "nuked libido" does that mean 0 erections or just less horny?

       5 upvotes 5 days ago
      The user discusses experiencing changes in libido and erections while on finasteride, noting that supplements like tongkat, citrulline, arginine, zinc, and vitamin D help maintain morning erections. Other users share varied experiences with finasteride, with some reporting reduced libido and weaker erections, while others notice no significant changes.

      community Found a slide summary for PP405

       35 upvotes 5 months ago
      PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

      community My personal thoughts on DHT. belive it or not

      1 year ago
      The conversation discusses a personal theory on the role of DHT in stress and reproduction, suggesting it converts testosterone for reproductive traits. The discussion includes skepticism and mentions individual differences in physiology and neurochemistry.