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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 5 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.
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      community This sub after taking Finasteride for one day

      in Satire  909 upvotes 5 months ago
      The conversation humorously discusses the side effects of finasteride, particularly sexual dysfunction. Users share mixed experiences, with some reporting issues and others not.

      community Proof that finasteride messes with neurosteroids

      in Research/Science  230 upvotes 6 months ago
      Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.
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      community Why balding gets worse in every generation?

      in Chat  81 upvotes 7 months ago
      Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.

      community How do people afford finasteride/dutasteride?

      in Treatment  27 upvotes 7 months ago
      People discuss the high cost of brand name finasteride and dutasteride, suggesting generics as cheaper alternatives. They share prices from various regions, highlighting significant cost differences.

      community Kevin Mann(Haircafe) is the GOAT

      in Update  416 upvotes 8 months ago
      A user praised Kevin Mann for his hair loss advice, crediting finasteride and minoxidil with tretinoin for saving their hair. Other users shared similar experiences and expressed frustration over Mann's channel being affected by past controversies.

      community How is there still no consensus on Topical Dutasteride in 2024?

      in Finasteride/Dutasteride  147 upvotes 8 months ago
      The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

      community Finasteride and minoxidil Dec 1st to may 10th

      in Is this regrowth?  392 upvotes 8 months ago
      The conversation is about someone's progress with hair regrowth using finasteride and minoxidil from December 1st to May 10th. They also mention using a topical treatment with a concentration of 0.004 per spray.

      community Clascoterone study going on right now

      in Research/Science  356 upvotes 8 months ago
      A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 9 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

      in Progress Pictures  224 upvotes 9 months ago
      A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

      community My hair journey from 2018-Today

      in Progress Pictures  42 upvotes 10 months ago
      The user shared their hair journey, expressing regret over inconsistent barber visits and haircuts that led to thinning. They are considering using a combination of Minoxidil and finasteride for treatment.

      community Increasing Oral Minoxidil Dose Over Time

      in Research/Science  95 upvotes 10 months ago
      A user reports hair loss despite using minoxidil and plans to increase their oral minoxidil dose gradually while also taking finasteride, dermarolling weekly, and applying topical stemoxydine nightly. They shared a link suggesting that increasing minoxidil dosage can improve hair growth and thickness.

      community Planning to for Hair transplant

      in Transplants  104 upvotes 10 months ago
      The conversation is about someone considering a hair transplant due to ineffective hair loss treatments, with suggestions ranging from trying a hairpiece to continuing with medications like finasteride and minoxidil, and waiting for new treatments. Some advise against a transplant due to the extent of hair loss and the cost, while others share different views on the effectiveness of transplants and non-surgical options.

      community The emotional cost of hair loss

      in Chat  213 upvotes 10 months ago
      A 21-year-old expresses feeling alone and invalidated in his struggle with hair loss, seeking empathy from others. Some users share similar feelings, while one mentions making progress with dutasteride and minoxidil treatments and considering a hair transplant.

      community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

      in Treatment  21 upvotes 10 months ago
      Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

      community Theory And Observation: Why Being Bald Can Really Work

      in Shaved/buzzed  88 upvotes 10 months ago
      The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

      community Progress - Min, Fin, and Nizoral.

      in Progress Pictures  340 upvotes 1 year ago
      The user shared progress photos showing hair regrowth after using Minoxidil, Finasteride, and Nizoral since mid-2023, and plans to replace derma rolling with Tretinoin. They discussed their routine, the initial shedding phase, and their experience with side effects, while others commented on the visible improvement.

      community 19 yo destroyed hairline even though using Fin/min/microneedling for 16months/11months/3months … Idk what to do.

      in Progress Pictures  260 upvotes 1 year ago
      A 19-year-old has been using finasteride, minoxidil, and microneedling to treat hair loss with no regrowth, feeling mentally affected by it. Advice given includes continuing treatment, considering a hair transplant, addressing potential vitamin deficiencies, and possibly switching to dutasteride or adding ketoconazole shampoo.

      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  65 upvotes 1 year ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.