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      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  295 upvotes 3 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community Anyone wanna try and interview the developers of RU?

      in Research/Science  84 upvotes 3 years ago
      The conversation discusses arranging an interview with the developers of RU58841 to clarify its safety and reasons for halted research, with some users expressing concerns about potential risks and others citing financial reasons for the discontinuation of studies. Specific treatments mentioned include RU58841, minoxidil, and finasteride.

      community find a cure for this shit already

      in Chat  207 upvotes 4 years ago
      Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hair loss, and the potential financial motivations of companies not wanting to find a cure.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 5 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Prediction: Scube3 is never coming out

      in Research/Science  7 upvotes 11 months ago
      Scube3, a potential hair loss treatment, is unlikely to be released because it was given to a startup company, Amplifica, which may go bankrupt and fail to bring the treatment to market. Amplifica is prioritizing other treatments over Scube3, which could lead to financial loss and the end of Scube3's development.

      community Hair Cloning, Trials were supposed to begin 2020-2021

      in Technology  48 upvotes 4 years ago
      The conversation discusses hair cloning trials expected to start in 2020-2021 and mentions concerns about potential delays due to the Coronavirus. Treatments like Minoxidil, finasteride, and RU58841 are referenced.

      community Topical Spironolactone 5% effectiveness

      in Product  2 upvotes 7 months ago
      Topical spironolactone 5% is being discussed for its effectiveness in treating hair loss, specifically receding temples. The user is inquiring if it works similarly to finasteride as a testosterone blocker.

      community The 6 Best Hair Loss Treatments of 2024, Tested by People with Thinning Hair

      in Product 8 months ago
      The conversation discusses various hair loss treatments, highlighting Advanced Trichology Topical Melatonin Hair Growth Serum, hers Minoxidil Foam, Keranique Hair Regrowth Treatment, Nioxin 5% Minoxidil, Virtue Minoxidil 5%, and Rogaine Women's 2% Minoxidil. One user suggests that the list may be influenced by sponsorship and emphasizes that minoxidil is commonly recommended but doesn't address the root cause of hair loss like finasteride or dutasteride.

      community Is topical Minoxidil not meant for frontal baldness?

      in Minoxidil  93 upvotes 2 years ago
      The effectiveness of topical Minoxidil for frontal baldness and the differences between brands. Suggestions are made to use Finasteride and RU58841 in combination with Minoxidil to help treat hair loss.

      community Final Result. 1 Year post Hair Transplant

      in Transplants  298 upvotes 2 years ago
      A user's experience with a hair transplant procedure and the resulting appearance of their hairline, which included some micro irregularities to make it look natural. Other users asked questions related to cost and safety of similar procedures at different clinics.

      community Tips/Advice on current situation aside from shaving bald

      in Progress Pictures  1 upvotes 3 years ago
      The user experienced worse hair after removing a wig system and has been using Hairband 82 Comfort Flex, Hair Max supplements, dermarolling, and a scalp massager for 4 months without clear results. They are hesitant to use Minoxidil due to shedding concerns and avoid finasteride due to side effects, preferring Saw Palmetto instead.

      community Should I stop using minoxidil?

      in Minoxidil  19 upvotes 4 years ago
      A 19-year-old user discusses using finasteride and switching from procapil to minoxidil, experiencing hair shedding and considering stopping minoxidil due to cost and effectiveness concerns. A reply suggests discontinuing minoxidil and continuing with finasteride alone.

      community My summation of PP405 - looks promising

      in Research/Science  194 upvotes 1 month ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 5 months ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.