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    GlossaryFibrous plaque

    thickened tissue area formed due to injury or inflammation

    Fibrous plaque refers to a thickened, hardened area of tissue that forms in response to injury or inflammation, often within blood vessels or the penile tissue in conditions like atherosclerosis or Peyronie's disease. This plaque is composed of collagen and other fibrous proteins, leading to reduced elasticity and potential functional impairment in the affected area.

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      community 22 | ~34 Months Finasteride Update

      in Progress Pictures  809 upvotes 1 month ago
      A user shared their 34-month update on using finasteride for hair loss, noting they maintained regrowth even after stopping minoxidil a year ago. Other users shared similar experiences and expressed admiration for the results.

      community Verteporfin and Microneedling

      in Treatments 3 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community 5 years on Finasteride, 1.5 years on Minoxidil Foam

      in Progress Pictures  706 upvotes 7 months ago
      The user has been using finasteride for five years and minoxidil foam for 1.5 years to combat hair loss, experiencing significant regrowth after an initial shedding phase with minoxidil. They shared progress pictures and discussed treatment experiences, including the addition of minoxidil to their regimen after noticing reduced efficacy with finasteride alone.