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Glossary Excipients

inactive substances aiding drug delivery and stability

Excipients are inactive substances used in medications to help deliver the active ingredient. They can serve various roles such as aiding in the drug's absorption, providing bulk, or enhancing stability. For example, in a tablet, excipients might include binders, fillers, and preservatives, ensuring the medication is effective and safe to consume.

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community Has anyone used Dutanol or Dutaheal (Indian generic) or other dutasteride tablets?

7 months ago

People are discussing switching to Indian generic dutasteride tablets like Dutanol and Dutaheal due to cost concerns, with some users reporting positive results when taken with a high-fat meal. Users have shared experiences with different brands, noting varying effectiveness and side effects compared to finasteride.

community How to increase Pyri concentration from 0.5% to 1% wihout using more volume ( 2ml x 2 per say for example )

in Chat 6 upvotes 2 years ago

OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.

community Topical finasteride making. Powder not disolving

4 upvotes 3 years ago

OP is trying to dissolve finasteride powder for a topical solution but faces issues with it not dissolving properly in ethanol or water. Users suggest methods like using a magnetic stirrer, shaking the mixture, or filtering out fillers, with some noting that finasteride is soluble in alcohol.

community Homemade fin - solubilization issue

1 upvotes 3 years ago

The user is attempting to create a topical finasteride solution by mixing crushed finasteride pills with minoxidil but is facing solubility issues. They are unsure if the finasteride has dissolved properly and are seeking advice on whether it is safe to use and if there is a solution to the problem.

community how to make dut pills from dut powder

7 months ago

A user discusses making DIY dutasteride capsules from powder bought from China, using a mix of MCT oil and propylene glycol. Others warn about the risks of incorrect dosing, potential degradation, and the possibility of receiving fake products.

community Out of curiosity, why are Finasteride pills formulated as small tablets, while Dutasteride pills are much larger soft gel capsules?

in Finasteride/Dutasteride 41 upvotes 1 year ago

Finasteride and Dutasteride are used for hair loss, with Dutasteride often in gel form for better bioavailability. Switching from Finasteride to Dutasteride is common, with some users combining treatments like Minoxidil for improved results.

community Korean minoxidil is superior to what we can get in the EU

261 upvotes 2 weeks ago

Korean minoxidil is preferred over Foligain due to its non-greasy, fast-drying formula that lacks propylene glycol, making it more pleasant to use. The user has been using minoxidil for over two years and finasteride for about ten months, but it's unclear how much the Korean minoxidil has contributed to their results.

community My nuclear skitzo hairloss stack

6 upvotes 6 months ago

The conversation discusses a hair loss treatment regimen involving high doses of dutasteride, finasteride, and minoxidil, with concerns about safety and potential side effects. Users advise against the excessive use of these medications, suggesting more moderate approaches and consulting a doctor.

community PSA: Not all Finasteride generics are created equal, effectiveness and severity of side-effects can vary by manufacturer.

1 year ago

Switching generic finasteride manufacturers can reduce side effects while maintaining effectiveness. Different fillers in generics may affect bioavailability and cause varying side effects.

community Switched Finasteride Brands, Hair, Scalp and Skin Declining

in Finasteride/Dutasteride 10 upvotes 1 year ago

Switching finasteride brands from Teva to Proscar led to hair and skin issues, suggesting possible differences in effectiveness or quality. Users recommend returning to the original brand that worked well.

community Minoxidil actually reduces wrinkles

in Research/Science 209 upvotes 1 year ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.

community Topical finasteride solution: Did my pharmacy simply dissolve finasteride tablets?

in Finasteride/Dutasteride 7 upvotes 2 years ago

A user received a topical finasteride solution from a pharmacy, which likely dissolved finasteride tablets instead of using pure finasteride powder, resulting in sediment. The user expressed dissatisfaction, expecting pure powder, and discussed the pros and cons of DIY solutions and the use of minoxidil with finasteride.

community Why isn’t Topical Dutasteride the “Gold Standard”?

172 upvotes 7 months ago

Topical dutasteride is more effective than finasteride for hair loss but lacks FDA approval and research, leading to less use. Users report varying effectiveness and side effects, with some preferring oral treatments.

community 2 years on Dutasteride/Minox, so much hair loss, not sure where to go from here

in Finasteride/Dutasteride 7 upvotes 8 months ago

The user has been experiencing increased hair loss despite using Dutasteride, Minoxidil, and microneedling, and is considering switching back to Finasteride. They are exploring other options like hair transplants, oral Minoxidil, and red light therapy but are concerned about side effects and effectiveness.

community Phase II topical dut study - outperforms oral fin with a minor DHT reduction

in Research/Science 61 upvotes 7 months ago

Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.

community From 21 to 23 years old. What do you think?

328 upvotes 7 months ago

A user is using oral finasteride, oral dutasteride, and drinking topical minoxidil for hair loss, despite health warnings. Switching from finasteride to dutasteride did not improve hair density.

community Almost 7 months of Topical Fin + Min

345 upvotes 9 months ago

A 24-year-old shared their 7-month progress using a topical solution of finasteride 0.1%, minoxidil 5%, and hydrocortisone butyrate 0.08%, along with ketoconazole shampoo, to treat hair loss, reporting no side effects and noticeable hair improvement. They also take vitamin D and biotin supplements, use a dermastamp, and manage Hashimoto's without thyroid medication.

community UPDATE: now 5 months on Dut and continuing to regress aggressively

in Finasteride/Dutasteride 218 upvotes 1 year ago

The user is experiencing significant hair loss after switching from finasteride to dutasteride for five months. Suggestions include that the hair loss might be a normal shedding phase, with some recommending continuing the treatment for up to 24 months or considering alternatives like RU58841.

community for anyone who is on the fence about oral minoxidil should read this NYT article it might help. it's an old one but people might need a refresher. https://www.nytimes.com/2022/08/18/health/minoxidil-hair-loss-pills.html

121 upvotes 1 year ago

Oral minoxidil is more effective than topical for hair regrowth but may cause unwanted body hair growth and cardiovascular side effects. Some users experience positive results, while others discontinue use due to side effects like chest pain.

community 10 months fin 1mg - not much if any progress :/

in Progress Pictures 80 upvotes 1 year ago

The user has been using finasteride for 10 months with no significant regrowth but no further hair loss and is considering adding oral minoxidil despite concerns about side effects. Other users suggest combining finasteride with minoxidil for better results, as finasteride prevents further hair loss while minoxidil aids regrowth.

community I just made 60x of 5mg minoxidil sugar cubes

1339 upvotes 1 year ago

A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

community Explanation for "dutasteride destroyed my hair"

7 upvotes 2 years ago

Dutasteride can drastically reduce sebum production, leading to dryer hair and shedding. Alternating shampoos and periodic silica supplementation can improve hair quality and thickness.

community So what’s really the deal with dutasteride hairline ruining claims?

in Finasteride/Dutasteride 72 upvotes 3 years ago

The potential effects of dutasteride on hair loss, with some users reporting it improved their hairline while others experienced worsened hair loss or shedding. Other treatments discussed include minoxidil and finasteride, as well as RU58841.

community PP405 (Everychem 3HP) Users - Assemble and share your story!

in Chat 19 upvotes 4 months ago

Users discussed the effectiveness of Everychem's solution, similar to PP405, with some reporting improved hair thickness and new growth. Concerns were raised about safety and the legitimacy of the product, with some users advising against purchasing research chemicals.

community clascoterone powder to topical diy

4 upvotes 4 months ago

The conversation is about making a topical solution from clascoterone powder, with references to using a RU58841 mixing guide for guidance. Concerns about product authenticity and bulk purchase requirements are also discussed.

community carriers other than PG for ru58841 ? Help !!

5 upvotes 1 year ago

The user is seeking alternatives to propylene glycol and glycerin for mixing with RU58841 due to allergies and greasiness. Suggestions include reducing glycerin and considering stemoxydine as a solvent.

community Making PG free solution at home

1 upvotes 2 years ago

A user wants to make a solution for RU58841 and finasteride powder using only glycerin and asks if ethanol is necessary. They are seeking advice on whether glycerin alone is sufficient.

community Why don't do it yourself topical solutions not talk about ethosomes as delivery mechanism?

4 upvotes 10 months ago

Ethosomes are suggested as an effective delivery method for topical finasteride solutions, requiring the addition of a phospholipid like soya lecithins. The user questions why do-it-yourself solutions don't commonly use ethosomes despite their potential benefits.

community PG free Ru58841 solvent in the UK

2 upvotes 3 weeks ago

The conversation discusses finding a PG-free solvent for dissolving RU58841 in the UK, with glycerin suggested as a potential alternative. Water is also mentioned as a possible option.

community Musely s Exosome formulation looks interesting

14 upvotes 1 year ago

Exosomes, cetirizine, melatonin, latanoprost, and caffeine are discussed as potential hair loss treatments. There is skepticism about the effectiveness of exosomes, especially in topical form, but some users report positive results.