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      community How is no one talking about this?

       6 upvotes 1 year ago
      Bovine colostrum is being discussed for its potential in hair regeneration, with some users noting that oral consumption may not be effective due to stomach acid destroying exosomes. The conversation also touches on ethical concerns about sourcing colostrum.

      community Amplifica: Hope or Cope? A Review of Their Pipeline

       9 upvotes 1 month ago
      Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

      community Is trichosol meant to smell like ginger beer?

       4 upvotes 2 years ago
      A user is using a trichosol-based minoxidil solution to avoid scalp irritation and is asking if it should smell like ginger beer. They like the scent and want to confirm they have the correct product.

      community Be careful about using non-PG based alternatives of Minoxidil (mathematically speaking, haven’t seen much practical studies)

      in Research/Science  7 upvotes 1 month ago
      Minoxidil formulations often use propylene glycol (PG) for stability and effectiveness, but PG-free alternatives like foams and PEG-based solutions can also be effective with less irritation. Concerns exist about the quality of PG-free minoxidil from lesser-known brands, especially from India, due to potential manufacturing issues.

      community Alfatradiol and Fluridil enough? Thoughs on topical fin?

       4 upvotes 2 years ago
      The user is currently using alfatradiol and fluridil for hair loss and is considering adding low-dose topical finasteride but is concerned about potential side effects due to past mental health issues. They are seeking others' experiences with these treatments and their effectiveness.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 7 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Looks like I’m allergic to propylene glycol..

       4 upvotes 4 years ago
      The user is experiencing an allergic reaction to propylene glycol in Kirkland minoxidil and is considering switching to a foam version or a low-PG minoxidil solution. They are also contemplating oral minoxidil but are concerned about its long-term safety.

      community Trial for TDM-105795 update from research office

       16 upvotes 2 years ago
      The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.

      community Alfatradiol only for mild thinning

       1 upvotes 10 months ago
      Alfatradiol is considered safe but less effective than finasteride for hair loss. One user reported subtle regrowth using alfatradiol with finasteride and minoxidil, while another found alfatradiol ineffective.

      community Thoughts on Avixis Alfatradiol?

       4 upvotes 4 years ago
      Avixis Alfatradiol is a topical 5-alpha reductase inhibitor available in Latin America and Germany, but its effectiveness is questioned. A user reported worsened hair loss after using it and recommended finasteride instead due to its proven effectiveness and lower cost.

      community Clascoterone - clearnet vendor

      in Chat  2 upvotes 8 months ago
      The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.

      community PP405 ON TEMU....seriously come on

      in Satire  145 upvotes 5 months ago
      A fake hair loss product called "PP405" is being humorously discussed, with users joking about its effectiveness and availability on resale websites. The consensus is that it's a scam, with some users sarcastically claiming miraculous results.

      community Making own RU58841 scalp lotion

       4 upvotes 2 months ago
      The conversation is about making and selling RU58841 scalp lotion by mixing the powder with ethanol and propylene glycol. The user is considering selling it as a lotion due to import restrictions in their country.

      community Finally live! alcohol-free, propylene glycol–free topical finasteride foam

       17 upvotes 10 months ago
      A new alcohol-free, propylene glycol-free topical finasteride foam is available for prescription in Canada and the USA, offering a cleaner alternative for hair loss treatment. The product also offers a combination of 0.1% finasteride with 5% minoxidil and aims to be affordable and less irritating for sensitive scalps.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       89 upvotes 10 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Topical finasteride in liposomal formulation

       6 upvotes 6 years ago
      Topical finasteride in a liposomal formulation reduces systemic absorption compared to ethanol solutions. The user is seeking sources for such products, noting that popular options like morr-f are not liposomal.

      community Best way to go about making a DIY topical fin for someone who's allergic to PG?

       1 upvotes 5 months ago
      A user allergic to propylene glycol seeks alternatives for a DIY topical finasteride solution, considering glycerin or glycerol-based vehicles. Another user suggests a recipe using propanediol, DMSO, MCT oil, and peppermint oil, incorporating minoxidil, dutasteride, and finasteride.

      community Update on Amplifica (new drugs) and Engraft (new hair transplant technology)

       65 upvotes 2 months ago
      Amplifica is developing new molecules for hair growth, with clinical trials expected soon, while Engraft Technologies is improving FUE robotic technology to make hair transplants faster and cheaper. Users express interest in the timeline for AMP-303 and concerns about high costs and effectiveness of current treatments.

      community Can I mix the Premixed RU58841 Solution into Alfatradiol?

       4 upvotes 2 years ago
      The user wants to mix 0.2 ml of RU58841 solution with 2 ml of Alfatradiol to use 10 mg of RU58841 daily due to concerns about side effects. They are asking if this combination would be effective for hair loss treatment.

      community Found this in a Facebook ad. Real stuff or a new snake oil? FLEAVA

       1 upvotes 2 years ago
      The conversation is about a product called FLEAVA, found in a Facebook ad, and whether it is effective or just another scam. One user believes it is likely a scam and mentions that such products usually don't compete with Minoxidil.

      community So is this the actual trial results for pp405?????

       94 upvotes 5 months ago
      PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.