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      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 5 months ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Reasons why Topical worked but Oral Minoxidil didn’t?

      in Minoxidil  16 upvotes 8 months ago
      Some people find topical minoxidil effective for hair loss, but oral minoxidil doesn't work for them, possibly due to absorption issues. Others have had better results with oral minoxidil, suggesting individual responses vary.

      community Update: Chest discomfort from RU58841

      in Update  34 upvotes 9 months ago
      A user experienced severe chest pains and shortness of breath after using RU58841 for hair loss and was advised by a doctor that blocking androgens can weaken the heart. They decided to continue with finasteride, minoxidil, and a hair transplant instead.

      community ~3 month update min/fin/dermaroll

      in Progress Pictures  33 upvotes 11 months ago
      The user reports hair growth improvements after using topical minoxidil, oral finasteride, and weekly dermarolling for about three months, but is experiencing dandruff, possibly due to the minoxidil.

      community Topical finasteride might be a lie

      in Research/Science 1 year ago
      The conversation discusses doubts about the effectiveness of topical finasteride for hair loss, suggesting that DHT could be produced elsewhere in the body and affect the scalp. It proposes that androgen receptor antagonists like spironolactone and clascoterone might be more effective as they could prevent this potential bypass mechanism.

      community Tretinoin Efficacy Alone for Hair Regrowth + DHT blocker

      in Minoxidil  5 upvotes 1 year ago
      Tretinoin's effectiveness for hair regrowth alone is questioned, with interest in its use with oral minoxidil. The discussion also considers whether finasteride or dutasteride is the better DHT blocker and if switching to dutasteride is advisable for those without side effects from finasteride.

      community TrichoGene minoxidil response test?

      in Minoxidil 1 year ago
      The conversation is about the legitimacy and affordability of ordering a Minoxidil response test from TrichoGene, an India-based company, as an alternative to Daniel Alain. The user is seeking feedback on whether TrichoGene is a reliable option.

      community Fin + Min - 18 month results. Also started using natural supplements and caffeine shampoo and have new miniaturised hairs all around the hairline. Hair transplant booked for end of the month.

      in Progress Pictures  34 upvotes 1 year ago
      The post discusses an 18-month hair regrowth journey using finasteride and minoxidil, along with natural supplements and caffeine shampoo, showing new hair growth around the hairline. The individual has also scheduled a hair transplant for the end of the month.

      community Oral Minoxidil Experience (2 months, 1 week in)

      in Minoxidil  6 upvotes 2 years ago
      The user shared their experience with oral minoxidil for hair loss, noting initial shedding but some improvement in hair thickness and coloration. They also use dutasteride, RU58841, topical minoxidil, a laser hat, dermapen, Nizoral, caffeine shampoo, castor oil, vitamins, and MSM tablets.

      community Ingest topical minoxidil by mouth ?

      in Minoxidil  6 upvotes 2 years ago
      A user questions if ingesting topical minoxidil could be an alternative to oral minoxidil for hair loss. Another user reports success with this method, noting they saw results and experienced no adverse effects.

      community my own advise on what has worked for me

      in Chat  15 upvotes 3 years ago
      The user recommends washing hair twice daily with glycerin soap, using finasteride and minoxidil, avoiding cigarettes and alcohol, and maintaining a diet rich in fruits and vegetables. They claim these methods have significantly improved their hair health over 25 years.

      community Similar 5ar inhibitors to fin?

      in Finasteride/Dutasteride 3 years ago
      Natural vitamins like pumpkin seed oil, saw palmetto, and ecklonia cava are discussed for their potential to lower DHT levels. They may work similarly to finasteride but are significantly weaker.

      community Best shampoo and conditioner for hair loss

      in Product  6 upvotes 5 months ago
      The user is using minoxidil, finasteride, Nizoral 2%, and microneedling for hair loss but finds Nizoral drying. They seek affordable shampoo and conditioner recommendations, with one reply suggesting baby shampoo for non-Nizoral days.

      community Give finasteride time to work!

      in Progress Pictures  298 upvotes 5 months ago
      A user shared their 2-year experience with finasteride for hair loss, noting initial success, a period of shedding, and eventual improvement. Another user mentioned seeing no improvement until 14 months in, emphasizing the need for patience.

      community Finally regrowth on the crown of my head after five years and switch to Dut!

      in Progress Pictures  25 upvotes 7 months ago
      After five years of no progress with hair regrowth using oral finasteride and topical minoxidil, a person switched to a combination of topical dutasteride, minoxidil, tretinoin, ketoconazole, and hydrocortisone in November 2023 and finally saw results. They had previously experienced side effects like gynecomastia from finasteride.

      community 1 Year on Fin, 2 months on Min

      in Progress Pictures  35 upvotes 7 months ago
      The user has been using 1mg finasteride daily, 0.05% tretinoin, and 5% topical minoxidil for hair loss. They've seen hairline recession with minoxidil but also new baby hairs, indicating a positive response.

      community Am I the chosen one? Minoxidil experience.

      in Research/Science  25 upvotes 11 months ago
      A user applied Minoxidil foam to their face to grow a beard and experienced increased hair density and darker hair as unintended benefits, despite initially using it for diffuse thinning on the scalp. Another person suggested that the user's heart rate increase might indicate a high conversion rate of Minoxidil to its active form, similar to taking oral Minoxidil.

      community Can hair thinning be reversed?

      in Finasteride/Dutasteride  36 upvotes 1 year ago
      The conversation is about the effectiveness of Dutasteride (Dut) and Minoxidil (Min) in reversing hair thinning. The user has been using Dut for 3 months and Min for a couple of years, and while hair fall has reduced, thinning continues. Other users suggest that Dut can reverse hair thinning over time, possibly beyond a year, and the outcome depends on individual body reactions and the degree of hair miniaturization.

      community Anything you use without scientific backing, just trusting your gut?

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

      community Buzzed my hair today. Raised my confidence a lot.

      in Shaved/buzzed  428 upvotes 2 years ago
      A user who buzzed their hair, raising their confidence. Other users suggested trying finasteride to thicken the existing hair or using hair systems as an alternative. Additionally, toppik was suggested as a way to fill in thinning areas.