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Did you mean Dystrophic Hairs?

Glossary Dystrophic Hairs

hairs damaged or weakened by underlying scalp conditions

Dystrophic hairs are hairs that have been damaged or weakened, often due to underlying conditions such as alopecia areata or other scalp disorders. These hairs typically appear thin, fragile, and may break easily, reflecting a disruption in the normal hair growth cycle. For professionals, the presence of dystrophic hairs can be a diagnostic clue indicating an active disease process affecting the hair follicles.

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community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 2 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community Hair Loss Ruins Your Mind: 10x rate of BDD. PF S is not real

in Research/Science 39 upvotes 7 months ago

Hair loss is linked to a higher rate of body dysmorphic disorder (BDD), OCD, and depression. Finasteride and dutasteride are not linked to increased suicidal risk, though some users report mental health side effects.

community What is up with all these body dysmorphic posts lately?

in Chat 49 upvotes 1 year ago

The conversation discusses concerns about body dysmorphia related to hair loss, with some users expressing frustration over posts claiming treatments like finasteride and dutasteride are ineffective or harmful despite minimal hair loss. It emphasizes the importance of early treatment with medications like finasteride and minoxidil for those experiencing hair loss.

community Hairloss is mentally exhausting

24 upvotes 5 years ago

The conversation is about the mental toll of hair loss and seeking alternatives to finasteride. Suggestions include using minoxidil, considering pumpkin seed oil, and possibly seeking counseling for body dysmorphic disorder.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Hair Loss "a matter of survival" in South Korea

335 upvotes 8 months ago

South Korea's president is advocating for hereditary hair loss to be covered by national health insurance due to its impact on mental health and daily functioning. The discussion highlights the societal pressure in South Korea regarding appearance and the potential benefits of treating hair loss to improve mental health.

community Hair Loss Causes Depression. Not Finasteride.

187 upvotes 7 months ago

Finasteride and Dutasteride do not cause depression or mood disorders; hair loss itself may be a more significant factor. Some users experience side effects from Finasteride, but it is generally well-tolerated.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 1 year ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Confession/Mini-Rant: I haven’t cut my hair since I started balding

6 upvotes 7 years ago

The conversation discusses coping with hair loss, with the original poster using finasteride and derma rolling as treatments. They express insecurity about their appearance, choosing to grow their hair long to hide balding, while others suggest different hairstyles and self-care strategies.

community PP405 vs Hair Cloning – Which Would Be Better for NW7 to NW1?

in Research/Science 20 upvotes 1 year ago

PP405 and hair cloning are discussed as potential treatments for reversing hair loss from Norwood 7 to Norwood 1. Hair cloning is seen as a more permanent solution, while PP405's effectiveness and long-term effects remain uncertain.

community Hair loss is holding me back from enjoying life and I'm wasting away my youth

279 upvotes 5 months ago

A 31-year-old man feels depressed due to hair loss, using topical finasteride and previously tried minoxidil. Others suggest treatments like finasteride, minoxidil, hair transplants, or embracing baldness, highlighting the importance of mental health and self-acceptance.

community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

community [13-Year Hair Loss Journey – Reached Norwood 7, Trying Again in 2025 (Male, 32, Vietnam)]

245 upvotes 10 months ago

A 32-year-old man from Vietnam, at Norwood 7 hair loss, is using Minoxidil, Finasteride, rosemary oil, NMN, and CoQ10 to regrow hair. Despite minor improvements, alternatives like hair systems or accepting baldness are suggested due to advanced hair loss.

community What is up with Dutasteride making peoples hair loss worse

35 upvotes 2 weeks ago

Switching from finasteride to dutasteride often causes increased hair shedding initially. Dutasteride is stronger but takes longer to show results, leading to concerns about worsening hair loss during the transition.

community I am about to cry, umI hate my gens

in Chat 58 upvotes 1 year ago

Hair loss affects confidence, with discussions on treatments like finasteride, minoxidil, and RU58841. Emphasis is placed on self-acceptance and building confidence beyond appearance.

community A Different Take on Curing MBP

16 upvotes 7 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community DHT is making fun of you, let's not suffer!

17 upvotes 11 months ago

DHT negatively affects scalp hair while promoting body hair growth, causing frustration due to the lack of permanent solutions for baldness. Users discuss treatments like finasteride and potential future solutions like CRISPR technology.

community Losing ground on dut, daily for 5 months after fin and min for a year.

in Finasteride/Dutasteride 92 upvotes 1 year ago

The user experienced increased hair thinning after switching from finasteride and minoxidil to dutasteride, despite some users suggesting it might be a temporary shedding phase. The user is considering using RU58841 but is unsure about its safety.

community My Delusional Hope - This page becomes irrelevant in 2030s

54 upvotes 10 months ago

People are hopeful for a permanent hair loss solution by the 2030s, considering options like hair cloning and treatments like pp405. Synthetic hair transplants have been attempted but are not effective long-term.

community Potential ( but not yet confirmed ) pp405 leak through korean media.

233 upvotes 10 months ago

A peptide-based hair loss treatment, PP405, reportedly increased hair density by 62% in 90 days, but these claims are unverified and met with skepticism. Users compared PP405 to Minoxidil and Finasteride, expressing doubts about its effectiveness without more evidence.

community 2 Years of Dut. Can these miniaturized hairs still recover?

150 upvotes 2 months ago

A user shared their experience with hair loss treatment using dutasteride for 2 years and oral minoxidil for 1.5 years, noting some regrowth but not full recovery in temple areas. Suggestions included microneedling, topical minoxidil, and considering a hair transplant for further improvement.

community How Veradermics secured a total of $220 million in series B and C financing for oral minoxidil, I will never understand.....

in Chat 38 upvotes 10 months ago

Veradermics' oral minoxidil shows promise for hair regrowth, with some users reporting significant improvements, while Pelage's PP405 results are less convincing and lack transparency. There is skepticism about both treatments' long-term effectiveness and potential side effects.

community Is it possible to create an estrogen mesotherapy/topical that doesn't go systemic?

7 upvotes 1 year ago

The conversation discusses the potential of using topical estrogen treatments for hair loss without systemic absorption, highlighting challenges and possible solutions like using estriol. It also mentions other treatments like topical finasteride, microneedling, and scalp massage, while noting the limitations and side effects of current options.

community 5MG finasteride everyday June 1st 2024 - October 7th 2024

in Progress Pictures 182 upvotes 1 year ago

The user has been using 1.25 mg of finasteride daily since June 2024 to promote hair regrowth and thickness, considering switching to dutasteride if results are unsatisfactory. They are hesitant to add minoxidil due to cost and potential side effects but have seen some progress with finasteride alone.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community Switched from fin 1mg to dut 0.5mg

in Is this regrowth? 39 upvotes 1 year ago

The user switched from finasteride to dutasteride and experienced noticeable hair regrowth without side effects, though some users questioned the necessity of such a potent treatment given the minimal hair loss. The conversation also touched on potential side effects of dutasteride, such as reduced sperm quality, but the user reported no issues.

community 7 years on Fin… I’m tired of this

in Progress Pictures 25 upvotes 1 year ago

The user has been on finasteride for 7 years and had a hair transplant, but is experiencing hair thinning and itchiness, particularly on one side, leading to concerns about male pattern baldness or other health issues. Despite having a full head of hair, the user is considering shaving it due to mental health struggles and is advised to consult a therapist and consider other treatments like minoxidil or dutasteride.

community Will PP405 need to be used indefinitely, like minoxidil?

31 upvotes 10 months ago

PP405 may not need daily use like minoxidil, but finasteride might still be needed to maintain hair regrowth. PP405 reawakens dormant hair follicles, potentially offering a long-term solution, though not a permanent cure.

community Well… I Did It. Estrogen Saved My Hairline

in Transgender 732 upvotes 1 year ago

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

community Giving up on ever feeling comfortable in my body

84 upvotes 5 years ago

The user has been using finasteride, dutasteride, and RU58841 for hair loss without success and feels extremely uncomfortable with their appearance, including being bald and short. They express deep unhappiness and social isolation. Suggestions from others include adopting stoicism, focusing on personal development, considering a hair system, improving fashion, working out, and seeking therapy for mental health.