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Dutasteride can drastically reduce sebum production, leading to dryer hair and shedding. Alternating shampoos and periodic silica supplementation can improve hair quality and thickness.

The conversation is about choosing between finasteride and minoxidil for hair loss treatment. Most users prefer finasteride, citing its effectiveness in stopping hair loss, while some mention using both for better results.

A user with kidney disease and high blood pressure experienced hair thinning, especially around the vertex. They are currently using finasteride and oral minoxidil but are considering whether to resume blood pressure medication despite managing symptoms with diet and exercise.

A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.

A female user is experiencing heavy hair shedding and receding temples, possibly due to low ferritin levels. She is using oral minoxidil, iron supplements, and ketoconazole shampoo, and is hesitant to start spironolactone.

User shared 2.5-year progress using finasteride for hair loss, showing significant improvement and reduced hair shedding. Persistence with finasteride led to thicker hair and fewer hair fall issues.

A user praised Kevin Mann for his hair loss advice, crediting finasteride and minoxidil with tretinoin for saving their hair. Other users shared similar experiences and expressed frustration over Mann's channel being affected by past controversies.

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

JW0061 shows superior hair growth results compared to existing treatments, with significant increases in hair follicles. The Wnt/β-catenin pathway is crucial for hair growth, and JW0061 activates this pathway effectively.

The conversation discusses using crushed finasteride tablets mixed with topical minoxidil for hair loss treatment. Users share their experiences and opinions on the effectiveness and proper concentration of this method.

A user shared progress pictures after 7 months on 1.5mg of finasteride, showing significant hair improvement. The user clarified they split 5 mg pills into quarters, resulting in a 1.33 mg dose.

The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hair loss.

A user increased their dutasteride dosage from 0.5mg to 1mg daily, resulting in a rise in DHT levels from 148 pg/mL to 281 pg/mL, and is considering switching back to finasteride due to continued hair loss. Replies suggest retesting and emphasize the importance of bloodwork before starting treatments.

Finasteride can continue to improve hair loss for up to 10 years, with the best results seen when started early. Combining treatments like minoxidil, dermarolling, or RU58841 may enhance effectiveness.

A user shared their hair recovery progress from ages 25-31, attributing success to quitting smoking, minoxidil, microneedling, and hormone therapy. They also mentioned being transgender and using hormone therapy.

The user cannot tolerate oral finasteride and is considering topical finasteride, minoxidil, microneedling, and RU58841 as alternative treatments for hair loss. They seek advice on whether these options are worth trying.

The user switched from topical minoxidil/dutasteride to oral dutasteride, resulting in hair loss. They resumed topical treatment without regrowth and are considering switching to finasteride due to poor results with oral dutasteride.

The conversation discusses natural DHT blockers like rice bran oil, which may reduce 5α-reductase activity similarly to Minoxidil and Dutasteride. One user argues that finasteride is more reliable and effective than natural alternatives.

A 22-year-old male has seen improvement in his hair loss after using 5% Minoxidil twice daily and dermarolling once or twice a week for 5 months. He no longer notices a bald spot in photos.

GT20029 showed significant hair growth and safety in phase II trials, with no adverse sexual events. Users are hopeful but concerned about future costs and systemic effects.

The user discusses their long struggle with hair loss, considering various treatments like hair transplants, hair systems, and natural methods such as micro-needling, vitamin supplements, and a healthy lifestyle. They express concerns about side effects from drugs like finasteride and ultimately lean towards using a hair system for better appearance and confidence.

A user on finasteride added dutasteride due to severe shedding and scalp issues, but didn't see reduced shedding. A dermatologist said finasteride doesn't reduce shedding but thickens hair, and another person confirmed shedding can continue but hair should improve over time.

The conversation provides advice on hair loss treatments, emphasizing the importance of following instructions for Minoxidil and Finasteride use, considering micro-needling to enhance treatment effectiveness, and incorporating hair oils, vitamins, and appropriate shampoos. The user shares their personal regimen, which includes oral Finasteride, topical Minoxidil, rosemary oil, micro-needling, supplements, and specialized hair care products, and stresses the necessity of consistency for successful results.

A user shared their 7-month hair regrowth progress using Minoxidil, Dutasteride, daily microneedling, and 9 vitamins, including vitamin E, D, C, B12, biotin, omega 3, and zinc. They also massage their scalp daily and use baby shampoo.

GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

The conversation discusses the availability of GT20029, a new topical hair loss treatment with fewer side effects than Minoxidil or finasteride. Users suggest using finasteride to preserve hair until GT20029 becomes available.

A 23-year-old man shared his one-year progress using finasteride for hair loss, starting with a lower dose due to side effects and gradually increasing to 1mg. He experienced manageable side effects and is considering adding minoxidil or switching to dutasteride in the future.

Finasteride, Minoxidil, Bioneer CosmeRNA, Technoderma, Kintor, Hope, Breezula, and Follicum treatments showed increases in hair count, with Technoderma showing the highest increase at 24.3 hairs/cm². Amplifica has not yet published results.

A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

After six months on 1.25 mg of finasteride, a user reports significant hair regrowth with no major shedding and uses a local brand of the medication. Some users inquire about side effects and brand differences, while others share their own experiences and concerns about hair loss treatment.