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PP405 is advancing to Phase 2b trials, showing promise from Phase 2a. It may be available in 3-6 years, with trials using a topical gel.

Hair loss treatments like dutasteride, finasteride, minoxidil, and RU58841 are discussed, with mixed results and ongoing hope for better solutions. Users express skepticism about a cure, sharing experiences with various treatments and lifestyle changes.

Bruce Willis's past comments on hair restoration and the progress of hair loss treatments like Minoxidil, Finasteride, and transplants. Users discuss the challenges of hair loss, the limited number of bald celebrities who are seen as role models, and the ongoing hope for future treatments.

The user reported positive progress in hair growth after taking 5 mg of oral minoxidil daily and 2.5 mg of dutasteride three times a week, with noticeable changes in hair fullness and body hair growth. They experienced initial side effects at a higher dosage but reported no side effects at the current dosage and plan to continue updating their progress.

RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

A 15-year-old experiencing hair loss and anxiety is using minoxidil and microneedling but is advised against starting finasteride or dutasteride due to age. The discussion emphasizes consulting a doctor, considering hormonal evaluations, and exploring non-medication coping strategies.

Starting finasteride earlier is generally more effective for hair loss, with no evidence of reduced effectiveness over time. Oral finasteride is recommended for better results, and starting treatment after age 18 is advised.

Verteporfin is being discussed for its potential to regrow hair and heal scars, possibly aiding hair transplants or replacing them. Some users are skeptical about its effectiveness, while others suggest combining it with microneedling for better results.

A user shared their positive experience using topical finasteride and minoxidil for nine months to combat male pattern baldness, reporting healthier and thicker hair without side effects. They recommend these treatments but advise researching potential side effects and consulting a professional.

The user switched from finasteride and topical minoxidil to dutasteride and oral minoxidil due to side effects but is experiencing further hair recession. They plan to double the dosage, despite mixed feedback on the effectiveness and potential side effects of the treatments.

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

An 18-year-old is considering starting minoxidil for hair loss due to a receding hairline but is hesitant about using finasteride due to age and lack of health insurance. A suggestion was made to use topical finasteride and minoxidil, along with lifestyle changes like exercise and cold showers.

A 25-year-old male using 1mg Finasteride and 5% Minoxidil for hair loss experienced stabilized scalp hair but began noticing beard shedding. Users suggest that Finasteride can slow beard growth, and some recommend using Minoxidil on the beard to counteract thinning.

Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

The user started a hair loss treatment with dutasteride, minoxidil, and dermarolling, experiencing some regrowth and satisfaction with progress. They also use nizoral shampoo and rosemary oil, and have not experienced significant side effects.

A 16-year-old considering finasteride for hair loss is advised to consult medical professionals due to age-related concerns, as they are currently using minoxidil and ketoconazole. Users suggest waiting until 17 or consulting a dermatologist for a professional opinion, with some recommending topical finasteride as an alternative.

The user switched from finasteride to dutasteride after experiencing significant hair shedding, and is also using oral minoxidil. Dutasteride helped stop the shedding, but it's too early to determine if it will reverse hair loss.

A user reported significant hair regrowth after 4 months using finasteride and minoxidil, with no major side effects. They are considering oral minoxidil and use microneedling and ketoconazole shampoo.

The conversation discusses the positive effects of taking finasteride (Propecia) for hair loss, with users sharing experiences of minimal side effects and improved hair growth over several years. The original poster emphasizes the importance of consistent use and mentions using Nizoral shampoo occasionally.

After switching from finasteride to dutasteride, the user noticed new hair growth and experienced manageable shedding. They reported feeling great on dutasteride with minimal side effects, using Cialis occasionally for libido issues.

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

AMP-303, a new injectable treatment for androgenetic alopecia, showed promising results in increasing hair count and density with minimal side effects. The treatment demonstrated significant hair regrowth and durability, offering new hope for those with hair loss.

Before getting a hair transplant, it's crucial to research and understand that ongoing treatments like finasteride, dutasteride, or minoxidil are necessary to maintain results. Concerns were raised about Turkish clinics, including overharvesting grafts, lack of regulations, and discouraging finasteride use.

OP believes RU58841 affected their thyroid, causing hypothyroidism and impacting minoxidil's effectiveness. They plan to start thyroid medication to improve hair regrowth.

The conversation discusses the effectiveness of 5% versus 10% minoxidil, especially when combined with tretinoin, for hair loss treatment. The user is also using oral minoxidil, derma stamping, and has previously used finasteride, but is unsure of the results.

The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).

The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

A doctor advised against using finasteride or dutasteride during pregnancy. The user continues with oral and topical minoxidil, microneedling, tretinoin, Nizoral, and pyrilutamide.